Frontiers in Cardiovascular Medicine

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Journal notices

Submission closing: Specialty Chief Editor's Collection on Non-Invasive Cardiovascular Imaging

Submissions close 30 May 2026—last call to join the collection curated by Sebastian Kelle, our Specialty Chief Editor for Cardiovascular Imaging, spanning AI diagnostics, genetics, cardiomyopathies, heart failure, and prevention

Rheumatic Heart Disease: global trends and emerging mechanisms

A preventable disease still claiming young lives. This ISACB-led collection explores RHD’s global epidemiology and the biology behind rheumatic valve injury—autoimmunity, fibrosis, sex-specific responses, omics, and vaccines. Submit by 30 September 2026.

Reimagining cardiac rehabilitation: lessons from history for a post‑MI future

Explore how cardiac rehabilitation evolved from strict bed rest to modern post‑MI care. Julie Redfern (University of Sydney) and Tom Briffa (University of Western Australia) trace its history and outline how programs must modernize for today’s patients

eBook of the month

Calcification is no longer a bystander. This eBook maps cardiovascular calcification across its clinical phenotypes—from coronary arteries to heart valves—and highlights emerging diagnostic tools and therapeutic targets.

When loop diuretics stop working: how to fight back against diuretic resistance

One in three heart failure patients fails to decongests despite aggressive diuretics. This review unpacks the mechanisms — from tubular adaptation to chloride depletion — and maps a phenotype-tailored playbook for cardiorenal syndrome.

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Frontiers in Cardiovascular Medicine

Submit your research

Author guidelines

Editor guidelines

Peer review

Publishing fees

Journal notices

Submission closing: Specialty Chief Editor's Collection on Non-Invasive Cardiovascular Imaging

Rheumatic Heart Disease: global trends and emerging mechanisms

Reimagining cardiac rehabilitation: lessons from history for a post‑MI future

eBook of the month

When loop diuretics stop working: how to fight back against diuretic resistance

Editors

masanori aikawa

hendrik tevaearai stahel

jun-ichi abe

elena aikawa

Articles

Comparative Diagnostic Performance and Stability of Deep Learning-and CFD-Based CT-FFR Across Vessels, Cardiac Phases, and Centers

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan

Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature

A protocol for the impact of Tongmai Jiangtang Capsules on the risk of cardiovascular and cerebrovascular events in metabolic syndrome

Atherosclerosis and Vascular Medicine

Comparative Diagnostic Performance and Stability of Deep Learning-and CFD-Based CT-FFR Across Vessels, Cardiac Phases, and Centers

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan

Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature

A protocol for the impact of Tongmai Jiangtang Capsules on the risk of cardiovascular and cerebrovascular events in metabolic syndrome

Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Syphilitic Coronary Ostial Lesions: A Single-Center Case Series

Exercise testing in athletes: An adjunct to diagnose arrhythmogenic cardiomyopathy?

The Effect of Aerobic Exercise on Blood Pressure in Patients with Resistant Hypertension: A Systematic Review and Meta-Analysis

The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value

Echocardiographic assessment of left atrioventricular coupling index: technical approaches and clinical implementation strategies

Machine learning-based methods in diagnosing cardiac amyloidosis: a meta-analysis

Association between SIRT1 gene polymorphisms and susceptibility to coronary artery disease: a systematic review and meta-analysis

Optimize speckle-tracking echocardiography screening in CKD patients: a TyG index-based nomogram model

Development of a risk score for intramyocardial hemorrhage in elderly STEMI patients after primary PCI: a retrospective cohort study with propensity score matching analysis

Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction

Arrhythmic risk stratification in post-myocardial infarction patients with preserved ejection fraction: long-term outcomes from the PRESERVE EF study

Case Report: Duchenne Muscular Dystrophy–Associated Cardiomyopathy Presenting as Adolescent Nonischemic Heart Failure—From Red-Flag Clues to Genetic Confirmation and Multisystem Management

Heart Valve Disease

Comparative Diagnostic Performance and Stability of Deep Learning-and CFD-Based CT-FFR Across Vessels, Cardiac Phases, and Centers

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan

Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature

A protocol for the impact of Tongmai Jiangtang Capsules on the risk of cardiovascular and cerebrovascular events in metabolic syndrome

Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Syphilitic Coronary Ostial Lesions: A Single-Center Case Series

Exercise testing in athletes: An adjunct to diagnose arrhythmogenic cardiomyopathy?

The Effect of Aerobic Exercise on Blood Pressure in Patients with Resistant Hypertension: A Systematic Review and Meta-Analysis

The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value

Echocardiographic assessment of left atrioventricular coupling index: technical approaches and clinical implementation strategies

Machine learning-based methods in diagnosing cardiac amyloidosis: a meta-analysis

Association between SIRT1 gene polymorphisms and susceptibility to coronary artery disease: a systematic review and meta-analysis

Optimize speckle-tracking echocardiography screening in CKD patients: a TyG index-based nomogram model

Development of a risk score for intramyocardial hemorrhage in elderly STEMI patients after primary PCI: a retrospective cohort study with propensity score matching analysis

Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction

Arrhythmic risk stratification in post-myocardial infarction patients with preserved ejection fraction: long-term outcomes from the PRESERVE EF study

Case Report: Duchenne Muscular Dystrophy–Associated Cardiomyopathy Presenting as Adolescent Nonischemic Heart Failure—From Red-Flag Clues to Genetic Confirmation and Multisystem Management

Cardiovascular Surgery

Comparative Diagnostic Performance and Stability of Deep Learning-and CFD-Based CT-FFR Across Vessels, Cardiac Phases, and Centers

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan

Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature

A protocol for the impact of Tongmai Jiangtang Capsules on the risk of cardiovascular and cerebrovascular events in metabolic syndrome

Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Syphilitic Coronary Ostial Lesions: A Single-Center Case Series

Exercise testing in athletes: An adjunct to diagnose arrhythmogenic cardiomyopathy?

The Effect of Aerobic Exercise on Blood Pressure in Patients with Resistant Hypertension: A Systematic Review and Meta-Analysis

The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value

Echocardiographic assessment of left atrioventricular coupling index: technical approaches and clinical implementation strategies

Machine learning-based methods in diagnosing cardiac amyloidosis: a meta-analysis

Association between SIRT1 gene polymorphisms and susceptibility to coronary artery disease: a systematic review and meta-analysis

Optimize speckle-tracking echocardiography screening in CKD patients: a TyG index-based nomogram model

Development of a risk score for intramyocardial hemorrhage in elderly STEMI patients after primary PCI: a retrospective cohort study with propensity score matching analysis

Predictive value of left atrial diameter and epicardial adipose tissue in sleep apnea and heart failure with preserved ejection fraction

Arrhythmic risk stratification in post-myocardial infarction patients with preserved ejection fraction: long-term outcomes from the PRESERVE EF study

Case Report: Duchenne Muscular Dystrophy–Associated Cardiomyopathy Presenting as Adolescent Nonischemic Heart Failure—From Red-Flag Clues to Genetic Confirmation and Multisystem Management

Thrombosis and Haemostasis

Comparative Diagnostic Performance and Stability of Deep Learning-and CFD-Based CT-FFR Across Vessels, Cardiac Phases, and Centers

Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan

Impaired lymphatic drainage in a child with hydrops fetalis and a novel variant in the PROX1 gene: case report and review of literature

A protocol for the impact of Tongmai Jiangtang Capsules on the risk of cardiovascular and cerebrovascular events in metabolic syndrome

Intravascular Ultrasound-Guided Percutaneous Coronary Intervention for Syphilitic Coronary Ostial Lesions: A Single-Center Case Series

Exercise testing in athletes: An adjunct to diagnose arrhythmogenic cardiomyopathy?