Frontiers in Cardiovascular Medicine

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Journal notices

Cardio-Kidney-Metabolic Syndrome: Clinical Recommendations

Heart, kidney, and metabolic disease do not exist in silos. Explore this expert Italian consensus on multidisciplinary CKM care, SGLT2i, and GLP-1RA titration.

Cracking the Amyloid Code: New Horizons in ATTR Cardiomyopathy

Breakthrough therapies and non-invasive scintigraphy are redefining cardiac amyloidosis care. Explore tafamidis outcomes, genetics, and novel stabilizers. Submit by 10 Oct 2026.

Reimagining cardiac rehabilitation: lessons from history for a post‑MI future

Explore how cardiac rehabilitation evolved from strict bed rest to modern post‑MI care. Julie Redfern (University of Sydney) and Tom Briffa (University of Western Australia) trace its history and outline how programs must modernize for today’s patients

Beyond Insulation: Active Roles of Epicardial and Brown Fat

Adipose tissue actively modulates coronary inflammation and remodeling. Explore molecular mechanisms, novel thermogenic targets, and metabolic therapies. Submit by 20 Mar 2027.

AI at the Bedside: Next-Gen Cardiac Imaging in Critical Care

Automated probe guidance, chamber segmentation, and hemodynamic classification bring expert echo precision to the ICU. Submit your AI imaging research by 31 Mar 2027.

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Frontiers in Cardiovascular Medicine

Submit your research

Author guidelines

Editor guidelines

Peer review

Publishing fees

Journal notices

Cardio-Kidney-Metabolic Syndrome: Clinical Recommendations

Cracking the Amyloid Code: New Horizons in ATTR Cardiomyopathy

Reimagining cardiac rehabilitation: lessons from history for a post‑MI future

Beyond Insulation: Active Roles of Epicardial and Brown Fat

AI at the Bedside: Next-Gen Cardiac Imaging in Critical Care

Editors

masanori aikawa

hendrik tevaearai stahel

jun-ichi abe

elena aikawa

Articles

Association Between Metabolic Syndrome Severity Score and Coronary Artery Disease Complexity Assessed by the SYNTAX Score in Patients With Chronic Coronary Syndrome

Balancing innovation and safety in percutaneous treatment of coronary artery calcification

Multi-Modal Neural Network for ECG Signal Classification in Coronary Artery Disease Using Gramian Angular Field

Translational maturity of artificial intelligence-enabled electrocardiography varies across cardiovascular diseases

Atherosclerosis and Vascular Medicine

Scoring balloon versus plain balloon vessel preparation before drug-coated balloon angioplasty for femoropopliteal atherosclerotic occlusive disease: a two-centre retrospective cohort study

Saint-Bonnet Doppler waveform classification system: a scoping review and evidence-based appraisal using AGREE II and AGREE-REX

Transcriptomic identification of mitophagy-related plaque markers HAND2, NRP1 and RNF213, with external replication and in vivo validation of MLXIP

Sitting Baduanjin-based rehabilitation programme following endovascular therapy in patients with chronic limb-threatening ischemia: protocol for a WeChat mini program-assisted multicentre randomized controlled trial

Vascular aging biomarkers: the role of ADMA, SDMA, and inflammation

Prognostic Performance of the WIfI Classification in Diabetic Patients with Infrapopliteal CLTI After Endovascular Revascularization: A Subgroup Analysis of the PRIME-WIFI Registry

Formononetin relieves chronic stress-related neointimal hyperplasia in mice by regulating HDAC6

Genetic-risk-informed integration of bulk and single-cell transcriptomes prioritizes ANPEP as a monocyte-associated candidate in aortic dissection

Retinal and coronary imaging in type 1 diabetes: links between retinopathy and subclinical cardiovascular disease

A chronological framework for atherosclerosis: from environmental pressure to clinical disease, with vascular aging as a cross-cutting dimension

OxLDL drives pro-inflammatory and foam cell-prone macrophage reprogramming via NF-κB/HIF-1β-dependent metabolic rewiring

Paclitaxel retention of drug-coated balloons in veins and arteries under arteriovenous fistula hemodynamics

A higher triglyceride-glucose index is independently associated with recent intraplaque hemorrhage in patients with severe carotid stenosis

Development and Validation of a Machine Learning-Based Model for Predicting Amputation Risk in Patients with Lower Extremity Arterial Disease and Diabetes

Effect of rosuvastatin and ezetimibe therapy on LDL-cholesterol reduction and non-invasive arterial injury markers in children with heterozygous familial hypercholesterolemia: a prospective, open-label, randomized study

Comparative midterm outcomes of contemporary revascularization strategies for acute lower limb ischemia: a retrospective cohort study

Heart Valve Disease

Fibrocalcific Phenotypes in Calcific Aortic Valve Disease: Imaging Characterization, Treatment Timing, and Efficacy Assessment

The right ventricle as the Achilles' heel: tricuspid regurgitation and right heart failure in the era of mechanical circulatory support

Long-term clinical and echocardiographic outcomes after mitral valve surgery for severe mitral annular calcification

Recipient Contributions to Primary Graft Dysfunction in Heart Transplantation

Challenging the guidelines: Longitudinal Trends in Left Ventricular Diameter and Function in Severe Aortic Regurgitation

Early changes in CT-derived quantitative flow ratio after transcatheter aortic valve replacement: a serial coronary physiological assessment

A screening method for aortic valve disease based on spectral analysis of a single-channel electrocardiogram using machine learning algorithms

Ventricular arrhythmic burden before and after mitral valve repair in mitral valve prolapse: the role of mitral annular disjunction

Multicenter experience of hybrid transcatheter pulmonary valve implantation in patients with a large right ventricular outflow tract

Pacing during TAVR through coronary wire in coronary artery and left ventricular wire

Distinct Designs, Complementary Strategies: Tendyne and SAPIEN M3 in Transcatheter Mitral Valve Replacement

Editorial: Investigating the role of extracellular vesicles in cardiovascular disease mechanisms

Editorial: Comprehensive approaches to multivalvular disease: diagnosis, treatment, and innovation

Pathogenicity assessment of a bicuspid aortic valve–associated ELASTIN variant using a zebrafish model

Study on the Construction and Application Effect of Discharge Preparation Services in Heart Valve Replacement Surgery

Simulation-guided outlet valve repair: early integration of computationally-derived principles of free-edge length in bicuspidization repair

Cardiovascular Surgery

Transjugular implantation of a leadless pacemaker in a 97-year-old patient with severe kyphosis and tortuous femoral veins: a case report

Case Report: Brucella-associated complications following thoracic endovascular aortic repair: a case series of three patients

Home-based telerehabilitation after CABG: higher objectively verified adherence and 12-week functional outcomes in a single-center observational cohort

Update in Short-Term Mechanical Circulatory Support: Indications, Devices and Complications

Integrative Bulk and Single-Cell Transcriptomic Analysis Identifies a PLAUR-Centered Macrophage-Associated Programmed Cell Death Signature in Type A Aortic Dissection

Staphylococcus aureus-associated infected subclavian artery pseudoaneurysm treated with dual bare-metal stent implantation: a case report

Case Report: Endovascular repair for true lumen collapse after frozen elephant trunk for type A aortic dissection

Impact of Perioperative Physical Exercise on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-Analysis

Emergent or urgent hybrid repair for complex thoracoabdominal aortic aneurysms: single-centre experience

Early Outcomes of Microaxial Flow Pump (Impella)–Supported Coronary Artery Bypass Grafting for Acute Myocardial Infarction with Cardiogenic Shock: National Reference Estimates from the J-PVAD Registry

Risk factors for aortic disease combined with coronary artery disease and the significance of preoperative coronary assessment in endovascular aortic repair

Effect of delayed remote ischemic preconditioning on major cardiovascular and cerebrovascular events in major vascular surgery: the protocol of DRIPC randomized controlled trial

Correction: Impact of left subclavian artery management on surgical efficiency and perioperative cerebral infarction in type A aortic dissection under deep hypothermic circulatory arrest: a single-center retrospective cohort study

External validation of EuroSCORE II, additive EuroSCORE, and the STS predicted risk of mortality at 2,600 meters above sea level: a retrospective cohort study from a Latin American cardiac surgery centre

Standardized 4-Step Surgical Approach to Address Atrial Fibrillation During Coronary Artery Bypass Grafting in a Patient with Severely Reduced Left Ventricular Function: A Case Report

Novel Techniques in the Prophylaxis and Treatment of Type II Endoleaks: A narrative review

Thrombosis and Haemostasis

Development of a multidisciplinary service-delivery framework for venous thromboembolism prevention in hospitalized medical patients with lung cancer: a mixed-methods modified Delphi study

Anatomical distribution of lower-extremity deep vein thrombosis and pulmonary embolism: a retrospective study with finite-element analysis of calf muscle-vein mechanics

Chamber-specific long-term prognosis of intracardiac thrombus: a 21-year propensity-matched cohort study

The role of VWF/ADAMTS13 axis in COVID-19-associated coagulopathy

Acute Pulmonary Embolism Complicating Tracheobronchial Tuberculosis: A Case Series of Five Patients

"Inflammation–Thrombosis Dissociation": A Retrospective Study of Early DVT Differences After UKA Between Han Chinese and Tibetan Patients at High Altitude