Frontiers in Aging Neuroscience

Original Research

Published on 19 Nov 2025

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

in Alzheimer's Disease and Related Dementias

Zhou Su
Mengran Liu
Jun Kuai
Tingting Yi
Yuechang Zheng
Xinran Bao
Jiyu Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630826

1,037 views

Original Research

Published on 19 Nov 2025

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Lingling Lv
Lixia Qin
Shenglan Hu
Changlian Tan
Haiyan Liao
Hainan Zhang
Feng Ren
Chunyu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657723

1,312 views

Original Research

Published on 17 Nov 2025

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

in Neuroinflammation and Neuropathy

Minchul Kim
Chongwon Pae
Joon Ho Moon
Inpyeong Hwang
Kyu Sung Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676721

1,821 views

Correction

Published on 17 Nov 2025

Correction: Current application status of non-invasive brain stimulation techniques in Alzheimer's disease: a bibliometric analysis

in Alzheimer's Disease and Related Dementias

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Tao Yu
Yulin Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1730649

1,212 views
1 citation

Review

Published on 17 Nov 2025

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review

in Neurocognitive Aging and Behavior

Qin Shi
Wei Wu
XiaoQin Sun
YingHai Liu
JingZheng Zeng
WeiQing Li
XueMei Dai
Gu Gong
QingQing Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1710009

1,726 views

Systematic Review

Published on 17 Nov 2025

Effect of various acupuncture courses for upper limb motor dysfunction after ischemic stroke: a Bayesian network meta-analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Can Wang
Pei Yu
Yuqi Tang
Yaning Liu
Jiangwei Shi
Xuhui Yang
Zihan Yin
Ling Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1668293

1,968 views

Original Research

Published on 14 Nov 2025

Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment

in Neurocognitive Aging and Behavior

Boung Chul Lee
Young Min Choe
Ji-Hyun Kim
Hye Ji Choi
Guk-Hee Suh
Shin Gyeom Kim
Hyun Soo Kim
Jaeuk Hwang
Dahyun Yi
Jee Wook Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646298

1,169 views

Systematic Review

Published on 14 Nov 2025

Effects of glucocerebrosidase gene variations on the risk of Parkinson’s disease dementia: a meta-analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Qiujie Li
Zhumei Bi
Weiming Liang
Shan Yin
Huaicheng Li
Zhongyou Liang
Minyao Wu
Jieru Quan
Cheng Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671760

1,447 views

Review

Published on 14 Nov 2025

Structural and microstructural changes in white and gray matter across the Alzheimer’s disease continuum

in Alzheimer's Disease and Related Dementias

Lingling Lv
Hui Guo
Zhiru Zhao
Xiongfei Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693840

1,771 views

Systematic Review

Published on 13 Nov 2025

Correlation of cognitive dysfunctions and diffusion tensor MRI measures in subjects with RRMS

in Neurocognitive Aging and Behavior

Alessio Mirabile
Carla Susinna
Giovanni Luca Cipriano
Giangaetano D’Aleo
Carmela Rifici
Edoardo Sessa
Angelo Quartarone
Viviana Lo Buono

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1661821

1,233 views

Original Research

Published on 13 Nov 2025

Glymphatic system impairment in cerebral small vessel disease: associations with perivascular space volume and cognition

in Neurocognitive Aging and Behavior

Lulu Ai
Zhiwei Li
Huipeng Huang
Chaojuan Huang
Shujian Chen
Xia Zhou
Xiaoqun Zhu
Zhongwu Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1680094

1,898 views
2 citations

Original Research

Published on 13 Nov 2025

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

in Alzheimer's Disease and Related Dementias

Hao Zhang
WenJun Chen
ShuYou Yuan
Bo Cai
ShaoXiang Ding
HongXia Bao
JunKai Sun
Wei Lu
HaoGang Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1597511

1,851 views
1 citation

Original Research

Published on 13 Nov 2025

Excitatory-inhibitory imbalance in temporal lobe epilepsy: a 5T multimodal MRI biomarker for focus localization and drug resistance stratification

in Neurocognitive Aging and Behavior

Zhaodi Huang
He Deng
Ying Xu
Lu Shi
Qingjun Jiang
Ke Xue
Ling Li
Ying Wei
Xiaona Xia
Xiangshui Meng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660608

1,438 views

Correction

Published on 12 Nov 2025

Correction: Five-year dementia prediction and decision support system based on real-world data

in Alzheimer's Disease and Related Dementias

Themis P. Exarchos
George A. Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
Vasiliki Mahairaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1719723

1,056 views

Original Research

Published on 12 Nov 2025

Diagnostic utility and psychometric properties of the Technology Activities of Daily Living Questionnaire (T-ADLQ) in people with non-formally educated with Alzheimer’s disease in Lima, Peru

in Neurocognitive Aging and Behavior

Rosa Montesinos
Loreto Olavarria
Fernando Henriquez
Diego Chambergo-Michilot
Belén Custodio
Carolina Delgado
Marco Malaga
Nilton Custodio
Andrea Slachevsky

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660345

1,436 views

Original Research

Published on 11 Nov 2025

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Andrea Riberas-Sánchez
Soleil García-Brito
Laia Vila-Solés
Laura Aldavert-Vera
Pilar Segura-Torres
Gemma Huguet
Gemma Carreras-Badosa
Elisabet Kádár

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671196

1,429 views

Original Research

Published on 11 Nov 2025

Increased free water in the nucleus basalis of Meynert is associated with worse olfaction in idiopathic Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Kai Wei
Shuyue Wang
Cheng Zhou
Peiyu Huang
Chao Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1689150

1,122 views

Original Research

Published on 11 Nov 2025

Interpretable machine learning for cognitive impairment prediction in Parkinson’s disease: a multicenter validation study with SHAP analysis

in Parkinson’s Disease and Aging-related Movement Disorders

Ziyuan Wang
Junqiang Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1688653

1,822 views

Original Research

Published on 10 Nov 2025

Brain activity during cognitive-motor tasks in older adults with cognitive frailty: a fNIRS study

in Neurocognitive Aging and Behavior

Yin-Hsiang Wang
Yea-Ru Yang
Nai-Chen Yeh
Pei-Yun Li
Ray-Yau Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1682050

1,457 views

Original Research

Published on 07 Nov 2025

Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease

in Cellular and Molecular Mechanisms of Brain-aging

Faruk Hossen
Javier Hung
Hamza Odeh
Grace Y. Sun
James C. Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671986

2,345 views

Review

Published on 07 Nov 2025

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

in Alzheimer's Disease and Related Dementias

Si-yi Leng
Qi-hang Yang
Yang Yuan
Bingao Chen
Hongbao Chen
Weikang Ban
Jiahao Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1677896

2,229 views
1 citation

Original Research

Published on 07 Nov 2025

Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain

in Neuroinflammation and Neuropathy

Chaoqun Liu
Le Shen
Li Xu
Afang Zhu
Yuguang Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675725

1,550 views

Review

Published on 06 Nov 2025

Biological determinants of blood-based biomarker levels in Alzheimer’s disease: role of nutrition, inflammation, and metabolic factors

in Alzheimer's Disease and Related Dementias

Aparna Inamdar
Parashuram Bugadannavar
Mahesh Palled
Savita Umarani
Preeti Salve
Bannimath Gurupadayya
Priyanka Patil
Himanshu Sharma

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1614962

3,485 views
1 citation

Original Research

Published on 06 Nov 2025

Dynamic decline in estimated glomerular filtration rate associated with in-hospital mortality risk in acute ischemic stroke patients after endovascular therapy: evidence from a Chinese stroke center

in Neuroinflammation and Neuropathy

Yanping Lin
Jingjing She
Lijuan Cai
Lingfeng Yu
Shouyue Jin
Xingyu Chen
Weiwei Gao
Renjing Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1598371

1,198 views

7,803 articles

articles

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Correction: Current application status of non-invasive brain stimulation techniques in Alzheimer's disease: a bibliometric analysis

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review

Effect of various acupuncture courses for upper limb motor dysfunction after ischemic stroke: a Bayesian network meta-analysis

Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment

Effects of glucocerebrosidase gene variations on the risk of Parkinson’s disease dementia: a meta-analysis

Structural and microstructural changes in white and gray matter across the Alzheimer’s disease continuum

Correlation of cognitive dysfunctions and diffusion tensor MRI measures in subjects with RRMS

Glymphatic system impairment in cerebral small vessel disease: associations with perivascular space volume and cognition

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

Excitatory-inhibitory imbalance in temporal lobe epilepsy: a 5T multimodal MRI biomarker for focus localization and drug resistance stratification

Correction: Five-year dementia prediction and decision support system based on real-world data

Diagnostic utility and psychometric properties of the Technology Activities of Daily Living Questionnaire (T-ADLQ) in people with non-formally educated with Alzheimer’s disease in Lima, Peru

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

Increased free water in the nucleus basalis of Meynert is associated with worse olfaction in idiopathic Parkinson’s disease

Interpretable machine learning for cognitive impairment prediction in Parkinson’s disease: a multicenter validation study with SHAP analysis

Brain activity during cognitive-motor tasks in older adults with cognitive frailty: a fNIRS study

Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease

Exercise modulation of gut microbiota in Alzheimer’s disease: pathophysiological mechanisms and therapeutic perspectives

Astrocytic Ror2-induced imbalance in brain and gut homeostasis contributes to chronic post-thoracotomy pain

Biological determinants of blood-based biomarker levels in Alzheimer’s disease: role of nutrition, inflammation, and metabolic factors

Dynamic decline in estimated glomerular filtration rate associated with in-hospital mortality risk in acute ischemic stroke patients after endovascular therapy: evidence from a Chinese stroke center