Frontiers in Aging Neuroscience

Original Research

Published on 19 Nov 2025

MRI-derived global small vessel disease burden serves as a marker of hippocampal sclerosis and clinical stage across the probable Alzheimer’s disease continuum

Ya-Che Chen
Ting-Bin Chen
Hsin-Chieh Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1692747

1,929 views

Mini Review

Published on 19 Nov 2025

Neuroimmune dynamics and brain aging: mechanisms and consequences

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1715045

2,272 views
3 citations

Original Research

Published on 19 Nov 2025

Delineation of the cognitive and neuropsychiatric features of Pisa syndrome in dementia with Lewy bodies

Zhou Su
Jun Kuai
Tingting Yi
Hao Wu
Jinghuan Gan
Zhihong Shi
Shuai Liu
Yong Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637930

1,297 views

Original Research

Published on 19 Nov 2025

Singing for memory: neural and cognitive effects of a choral intervention in older adults

Miriam Napadow
Håkan Fischer
Maria Sandgren
Máté Magyar
Zsuzsanna Lénárd
László Harmat
Örjan de Manzano

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1679873

3,062 views

Original Research

Published on 19 Nov 2025

Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl3

Shreshta Jain
Divya Vohora

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676926

2,004 views

Original Research

Published on 19 Nov 2025

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

Lingling Lv
Lixia Qin
Shenglan Hu
Changlian Tan
Haiyan Liao
Hainan Zhang
Feng Ren
Chunyu Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657723

1,353 views

Original Research

Published on 19 Nov 2025

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

Zhou Su
Mengran Liu
Jun Kuai
Tingting Yi
Yuechang Zheng
Xinran Bao
Jiyu Ji

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1630826

1,075 views

Original Research

Published on 17 Nov 2025

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Minchul Kim
Chongwon Pae
Joon Ho Moon
Inpyeong Hwang
Kyu Sung Choi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1676721

1,850 views

Review

Published on 17 Nov 2025

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review

Qin Shi
Wei Wu
XiaoQin Sun
YingHai Liu
JingZheng Zeng
WeiQing Li
XueMei Dai
Gu Gong
QingQing Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1710009

1,796 views

Correction

Published on 17 Nov 2025

Correction: Current application status of non-invasive brain stimulation techniques in Alzheimer's disease: a bibliometric analysis

Shan Cong
Meng Wang
Long Yan
Li Sun
Bowen Zheng
Jinying Xie
Tao Yu
Yulin Qian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1730649

1,241 views
1 citation

Systematic Review

Published on 17 Nov 2025

Effect of various acupuncture courses for upper limb motor dysfunction after ischemic stroke: a Bayesian network meta-analysis

Can Wang
Pei Yu
Yuqi Tang
Yaning Liu
Jiangwei Shi
Xuhui Yang
Zihan Yin
Ling Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1668293

2,030 views

Systematic Review

Published on 14 Nov 2025

Effects of glucocerebrosidase gene variations on the risk of Parkinson’s disease dementia: a meta-analysis

Qiujie Li
Zhumei Bi
Weiming Liang
Shan Yin
Huaicheng Li
Zhongyou Liang
Minyao Wu
Jieru Quan
Cheng Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671760

1,493 views

Original Research

Published on 14 Nov 2025

Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment

Boung Chul Lee
Young Min Choe
Ji-Hyun Kim
Hye Ji Choi
Guk-Hee Suh
Shin Gyeom Kim
Hyun Soo Kim
Jaeuk Hwang
Dahyun Yi
Jee Wook Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1646298

1,217 views

Review

Published on 14 Nov 2025

Structural and microstructural changes in white and gray matter across the Alzheimer’s disease continuum

Lingling Lv
Hui Guo
Zhiru Zhao
Xiongfei Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1693840

1,829 views

Systematic Review

Published on 13 Nov 2025

Correlation of cognitive dysfunctions and diffusion tensor MRI measures in subjects with RRMS

Alessio Mirabile
Carla Susinna
Giovanni Luca Cipriano
Giangaetano D’Aleo
Carmela Rifici
Edoardo Sessa
Angelo Quartarone
Viviana Lo Buono

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1661821

1,264 views

Original Research

Published on 13 Nov 2025

Glymphatic system impairment in cerebral small vessel disease: associations with perivascular space volume and cognition

Lulu Ai
Zhiwei Li
Huipeng Huang
Chaojuan Huang
Shujian Chen
Xia Zhou
Xiaoqun Zhu
Zhongwu Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1680094

1,957 views
2 citations

Original Research

Published on 13 Nov 2025

Excitatory-inhibitory imbalance in temporal lobe epilepsy: a 5T multimodal MRI biomarker for focus localization and drug resistance stratification

Zhaodi Huang
He Deng
Ying Xu
Lu Shi
Qingjun Jiang
Ke Xue
Ling Li
Ying Wei
Xiaona Xia
Xiangshui Meng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660608

1,478 views

Original Research

Published on 13 Nov 2025

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

Hao Zhang
WenJun Chen
ShuYou Yuan
Bo Cai
ShaoXiang Ding
HongXia Bao
JunKai Sun
Wei Lu
HaoGang Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1597511

1,886 views
1 citation

Correction

Published on 12 Nov 2025

Correction: Five-year dementia prediction and decision support system based on real-world data

Themis P. Exarchos
George A. Dimakopoulos
Konstantinos Lazaros
Marios Krokidis
Aristidis Vrahatis
Gerasimos Grammenos
Antigoni Avramouli
Konstantina Skolariki
Roy Adams
Vasiliki Mahairaki

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1719723

1,066 views

Original Research

Published on 12 Nov 2025

Diagnostic utility and psychometric properties of the Technology Activities of Daily Living Questionnaire (T-ADLQ) in people with non-formally educated with Alzheimer’s disease in Lima, Peru

Rosa Montesinos
Loreto Olavarria
Fernando Henriquez
Diego Chambergo-Michilot
Belén Custodio
Carolina Delgado
Marco Malaga
Nilton Custodio
Andrea Slachevsky

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1660345

1,459 views

Original Research

Published on 11 Nov 2025

Increased free water in the nucleus basalis of Meynert is associated with worse olfaction in idiopathic Parkinson’s disease

Kai Wei
Shuyue Wang
Cheng Zhou
Peiyu Huang
Chao Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1689150

1,142 views

Original Research

Published on 11 Nov 2025

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

Andrea Riberas-Sánchez
Soleil García-Brito
Laia Vila-Solés
Laura Aldavert-Vera
Pilar Segura-Torres
Gemma Huguet
Gemma Carreras-Badosa
Elisabet Kádár

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671196

1,457 views

Original Research

Published on 11 Nov 2025

Interpretable machine learning for cognitive impairment prediction in Parkinson’s disease: a multicenter validation study with SHAP analysis

Ziyuan Wang
Junqiang Yan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1688653

1,859 views

Original Research

Published on 10 Nov 2025

Brain activity during cognitive-motor tasks in older adults with cognitive frailty: a fNIRS study

Yin-Hsiang Wang
Yea-Ru Yang
Nai-Chen Yeh
Pei-Yun Li
Ray-Yau Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1682050

1,509 views

7,808 Publications

volumes

Volume 17 - 2025

MRI-derived global small vessel disease burden serves as a marker of hippocampal sclerosis and clinical stage across the probable Alzheimer’s disease continuum

Neuroimmune dynamics and brain aging: mechanisms and consequences

Delineation of the cognitive and neuropsychiatric features of Pisa syndrome in dementia with Lewy bodies

Singing for memory: neural and cognitive effects of a choral intervention in older adults

Decanoic acid, an MCT dietary component, alleviates cognitive impairment, cellular senescence, and promotes autophagy in accelerated aging and neurotoxic mouse models induced by chronic administration of D-galactose and D-galactose/AlCl3

Vitamin D-linked vulnerability and functional connectivity alterations in the superior frontal gyrus contributing to cognitive impairment in Parkinson’s disease

Dysfunctional default mode and visual networks underlie cognitive deficits in dementia with Lewy bodies: a resting-state fMRI study

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Research progress on the interaction between multiple organ-brain axes and perioperative neurocognitive disorders: a narrative review

Correction: Current application status of non-invasive brain stimulation techniques in Alzheimer's disease: a bibliometric analysis

Effect of various acupuncture courses for upper limb motor dysfunction after ischemic stroke: a Bayesian network meta-analysis

Effects of glucocerebrosidase gene variations on the risk of Parkinson’s disease dementia: a meta-analysis

Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment

Structural and microstructural changes in white and gray matter across the Alzheimer’s disease continuum

Correlation of cognitive dysfunctions and diffusion tensor MRI measures in subjects with RRMS

Glymphatic system impairment in cerebral small vessel disease: associations with perivascular space volume and cognition

Excitatory-inhibitory imbalance in temporal lobe epilepsy: a 5T multimodal MRI biomarker for focus localization and drug resistance stratification

Integrated analysis of N-glycosylation and Alzheimer’s disease: identifying key biomarkers and mechanisms

Correction: Five-year dementia prediction and decision support system based on real-world data

Diagnostic utility and psychometric properties of the Technology Activities of Daily Living Questionnaire (T-ADLQ) in people with non-formally educated with Alzheimer’s disease in Lima, Peru

Increased free water in the nucleus basalis of Meynert is associated with worse olfaction in idiopathic Parkinson’s disease

Intracranial self-stimulation mitigates spatial task deficits, modifies miR-146a and miR-495 serum levels and restores hippocampal NRF2 levels in a rat model of sporadic Alzheimer’s disease

Interpretable machine learning for cognitive impairment prediction in Parkinson’s disease: a multicenter validation study with SHAP analysis

Brain activity during cognitive-motor tasks in older adults with cognitive frailty: a fNIRS study