Frontiers in Aging Neuroscience

Original Research

Published on 03 Sep 2025

Corpus callosum microstructure in chimpanzees (pan troglodytes): associations with age, handedness and cognition

Maëlig Chauvel
Ivy Uszynski
Cyril Poupon
William D. Hopkins

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611611

1,722 views

Original Research

Published on 03 Sep 2025

Associations of plasma von Willebrand Factor levels with cognitive decline and neurodegeneration in older adults without dementia

Pan Fu
Meiling Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1595071

2,011 views

Systematic Review

Published on 03 Sep 2025

Effects of transcranial alternating current stimulation on neurophysiologic motor function in Parkinson’s patients: a systematic review and meta-analysis

Fangcheng Ye
Yinjin Shao
Guihua Wu
Miao Huang
Hui Huang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1621052

2,290 views

Review

Published on 02 Sep 2025

Associations between peripheral nerve stimulation and cognitive performance: insights from healthy individuals and various disease pathologies

Xing Liu
Chenyi Yang
Xinyi Wang
Zixuan Wang
Huihui Liao
Huan Liu
Miao Zhang
Lin Zhang
Haiyun Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1518198

3,375 views
1 citation

Mini Review

Published on 01 Sep 2025

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

Jie Lu
Tie-Jun Xian
Cheng-Jun Li
Yang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1671552

4,434 views
8 citations

Original Research

Published on 01 Sep 2025

Dual improvement of cognitive function and auditory ability in elderly patients with hearing impairment by transcranial direct current stimulation-assisted auditory rehabilitation training

Ying Zhou
Haolun Han
Xiaoli Zhang
Yiyan Zhang
Wenbo Duan
Liyun Su
Baowei Li
Zhezhe Sun
Lei Wang
Gang Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1591496

3,054 views

Original Research

Published on 29 Aug 2025

Abnormal sleep blood pressure patterns are associated with the diffusion tensor imaging along the perivascular space index in cognitively impaired individuals

Mariateresa Buongiorno
Gonzalo Sánchez-Benavides
Giovanni Caruana
Andrea Elias-Mas
Cristina Artero
Natalia Cullell
Pilar Delgado
Darly Milena Giraldo
Clara Marzal-Espí
Oriol Grau-Rivera

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1578270

2,902 views

Original Research

Published on 29 Aug 2025

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

Zihao Zhang
Qingpei Hao
Tao Wang
Shijun Peng
Xin Chang
Yuepeng Wang
Jia Ouyang
Ruen Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1658854

1,514 views

Mini Review

Published on 29 Aug 2025

Influence of biological sex on neuroinflammatory dynamics in the aging brain

Ludmila Müller
Svetlana Di Benedetto
Viktor Müller

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1670175

3,898 views
8 citations

Mini Review

Published on 29 Aug 2025

Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration

Kun Leng
Mervyn Maze
Odmara L. Barreto Chang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1632947

4,115 views
4 citations

Original Research

Published on 29 Aug 2025

Association between shift work and brain age gap: a neuroimaging study using MRI-based brain age prediction algorithms

Youjin Kim
Joon Yul Choi
Evgeny Petrovskiy
Wanhyung Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1650497

2,879 views

Original Research

Published on 26 Aug 2025

Longitudinal multimodal MRI analysis of lecanemab treatment in mild cognitive impairment: a pilot study of structural, perfusion, and microstructural changes

Toshiya Takahashi
Dinh Ha Duy Thuy
Shingo Takenaka
Sayaka Ono
Maya Fukui
Yasushi Okada
Tomohiko Asada
Kan Niimi
Kaku Kimura
Akio Ikeda

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1651596

3,256 views

Original Research

Published on 26 Aug 2025

HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia

Joanne K. Agus
Oscar M. Muñoz Herrera
Christopher H. Rhodes
Jack Jingyuan Zheng
Chenghao Zhu
Maurice Wong
Xinyu Tang
Izumi Maezawa
Lee-Way Jin
Carlito B. Lebrilla

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1629496

2,578 views

Brief Research Report

Published on 26 Aug 2025

Hand dexterity and mobility independently predict cognition in older adults: a multi-domain regression analysis

Thomas Rudolf Schneider
Ansgar Felbecker
Ben von Mitzlaff
Gregor Weissofner
Sarah Meier
Patrick Eggenberger
Simon Annaheim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1624307

2,347 views
1 citation

Original Research

Published on 26 Aug 2025

The expression and association of MATK in chronic hypoperfusion patients with white matter hyperintensity

Ming Zhao
Jiayue Zhang
Qianqian Yang
Lei Chen
Hongjian Shen
Yingyan Pu
Wei Wei
Yi Han
Ping Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570482

1,793 views
1 citation

Original Research

Published on 26 Aug 2025

Cognitive training gain transfer in cognitively healthy aging: per protocol results of the German AgeGain study

Florian U. Fischer
Bianca Kollmann
Dominik Wolf
Alexandra Sebastian
Kristel Knaepen
David Riedel
Andreas Mierau
Nicolas Ruffini
Kristina Endres
Jennifer Winter

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587395

2,237 views

Original Research

Published on 26 Aug 2025

Altered brain dynamics in post-stroke cognitive and motor dysfunction

Xiaoying Liu
Guihua Song
Xiaoyun Zhuang
Ying Zhang
Xiaoyang Wang
Yin Qin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1640378

1,971 views

Review

Published on 26 Aug 2025

Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson’s disease

Wei-Qi Li
Jia-Hua Yang
Lu-Lu Liu
Song-Tao Ding
Bin Yu
Lin Jiang
Ning Yan
Han-Deng Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1580029

3,828 views

Original Research

Published on 26 Aug 2025

Cognitive flexibility in aging: the impact of age range and task difficulty on local switch costs in task switching

Tara Radović
Sebastian Kübler
Rafael Mikolajczyk
Alexander Kluttig
Viktoria Maydych
Torsten Schubert

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1619441

2,461 views
1 citation

Review

Published on 25 Aug 2025

The manipulator behind “Scissors”: γ -secretase and its modulators in Alzheimer’s disease

Gao Ning
Xing Fan
Du Juan
Zhao wenxue
Wang Sijia
Chen Meinei
Dong Xiaolong
Qi Yiming

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1637671

4,045 views
2 citations

Correction

Published on 22 Aug 2025

Correction: A bibliometric analysis of the immune system and cognitive impairment: trends from 1985 to 2024

Beibei Zou
Jinxi Xiang
Muhua Zhang
Jing Huang
Chao Feng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1675716

1,768 views

Original Research

Published on 22 Aug 2025

Moderating role of triglycerides in the relationship between amyloid-β, hippocampal atrophy, and cognitive decline in mild cognitive impairment and early Alzheimer’s disease

Ji-Woo Seok
Kahye Kim
Soonjo Hwang
Kun Ho Lee
Jaeuk U. Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592341

2,577 views

Original Research

Published on 22 Aug 2025

Tooth loss impairs cognitive function in SAMP8 mice by aggravating pyroptosis of microglia via the cGAS/STING pathway

Xu Sun
Yunping Lu
Jiangqi Hu
Shixiang Meng
Xiaoyu Wang
Qingsong Jiang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1628520

2,578 views
2 citations

Review

Published on 20 Aug 2025

Pathophysiological insights and therapeutic developments in age-related hearing loss: a narrative review

Shichu Sun
Qi Zhao
Haojia He
Yujia Liu
Yuchong Nie
You Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1657603

6,041 views
3 citations

7,815 Publications

volumes

Volume 17 - 2025

Corpus callosum microstructure in chimpanzees (pan troglodytes): associations with age, handedness and cognition

Associations of plasma von Willebrand Factor levels with cognitive decline and neurodegeneration in older adults without dementia

Effects of transcranial alternating current stimulation on neurophysiologic motor function in Parkinson’s patients: a systematic review and meta-analysis

Associations between peripheral nerve stimulation and cognitive performance: insights from healthy individuals and various disease pathologies

The estrogen–brain interface in neuroinflammation: a multidimensional mechanistic insight

Dual improvement of cognitive function and auditory ability in elderly patients with hearing impairment by transcranial direct current stimulation-assisted auditory rehabilitation training

Abnormal sleep blood pressure patterns are associated with the diffusion tensor imaging along the perivascular space index in cognitively impaired individuals

Systemic inflammation versus clinical demographics: patient age surpasses the platelet-to-lymphocyte ratio in differentiating secondary trigeminal neuralgia

Influence of biological sex on neuroinflammatory dynamics in the aging brain

Emerging biomarkers of postoperative delirium at the intersection of neuroinflammation and neurodegeneration

Association between shift work and brain age gap: a neuroimaging study using MRI-based brain age prediction algorithms

Longitudinal multimodal MRI analysis of lecanemab treatment in mild cognitive impairment: a pilot study of structural, perfusion, and microstructural changes

HDL from 36-h fasted participants potently promotes efflux of cholesteryl ester from activated microglia

Hand dexterity and mobility independently predict cognition in older adults: a multi-domain regression analysis

The expression and association of MATK in chronic hypoperfusion patients with white matter hyperintensity

Cognitive training gain transfer in cognitively healthy aging: per protocol results of the German AgeGain study

Altered brain dynamics in post-stroke cognitive and motor dysfunction

Exercise as a multitarget therapy: modulating myokines, neurotrophins, and inflammation in Parkinson’s disease

Cognitive flexibility in aging: the impact of age range and task difficulty on local switch costs in task switching

The manipulator behind “Scissors”: γ -secretase and its modulators in Alzheimer’s disease

Correction: A bibliometric analysis of the immune system and cognitive impairment: trends from 1985 to 2024

Moderating role of triglycerides in the relationship between amyloid-β, hippocampal atrophy, and cognitive decline in mild cognitive impairment and early Alzheimer’s disease

Tooth loss impairs cognitive function in SAMP8 mice by aggravating pyroptosis of microglia via the cGAS/STING pathway

Pathophysiological insights and therapeutic developments in age-related hearing loss: a narrative review