Frontiers in Cell and Developmental Biology

Original Research

Published on 17 Feb 2026

Pharmacological inhibition of frizzled 4 delays cell cycle progression and limits oral squamous cell carcinoma growth

in Cancer Cell Biology

Riccardo Destefani
Ilaria J. Valookkaran
Sabrina Bensland
Christian T. Meisel
Cristina Porcheri

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1756565

201 views

Original Research

Published on 17 Feb 2026

Single-cell atlas reveals a pro-metastatic RELB+ neutrophil-myeloid subset underlying lymph node metastasis in EGFR-wildtype LUAD

in Cancer Cell Biology

Fasheng Li
Xiao Yang
Ang Li
Yutao Pang
Hongfei Zhang
Liyao Lin
Dong Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1766211

155 views

Original Research

Published on 17 Feb 2026

A putative prognostic model for lung adenocarcinoma based on crotonylation-related genes by bioinformatics and experimental verification

in Cancer Cell Biology

Wenting Wang
Baixiang Cui
Haoyue Li
Zihan Zhen
Xueqing Song
Xiaoyu Yuan
Qing Cui
Qi Yuan
Yong Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1639773

220 views

Original Research

Accepted on 16 Feb 2026

PRMT5 Inhibition Triggers Functional ATM Deficiency and Sensitizes Pancreatic Cancer to CHK1 Blockade

in Cancer Cell Biology

Madeline Dzikowski
Gareth Pollin
Veda Gunia
Shawna Butler
Byambasuren Enkhtuul
Jennifer Gavina Chavez
Michael T Zimmermann
Angela Mathison
Raul Urrutia
Gwen Lomberk

Frontiers in Cell and Developmental Biology

Review

Accepted on 16 Feb 2026

Cancer-associated fibroblast heterogeneity and its role in reshaping immunotherapy in solid cancers: potential strategies and clinical promise

in Cancer Cell Biology

Zhanwu Yu
Peng Zu

Frontiers in Cell and Developmental Biology

Mini Review

Accepted on 16 Feb 2026

From Mono-to Multi-Cellular In Vitro Models: Reconstructing Colorectal Cancer Complexity for Translational and Personalized Applications

in Cancer Cell Biology

Pier Giorgio Amendola
Gareth Owain Edwards
Francesco Saverio Li Causi
Giorgio Castagnola
Shailendra Singh

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 16 Feb 2026

Paeonol inhibits the development of oral squamous cell carcinoma through the PI3K/AKT signaling pathway

in Cancer Cell Biology

Changyue Liu
Xuelin Mou
Jiaming Liu
Wu Yuehan
Jinpeng Han
Ren Li
Yuxia Gao
Ying Liu

Frontiers in Cell and Developmental Biology

Mini Review

Accepted on 13 Feb 2026

Vascular endothelial cells as putative signaling niches for epithelial skin stem cells

in Cancer Cell Biology

Tudorita Tumbar
Torsa Ganguly
Cailin E. McMahon
Mohammad A. Tavallaei

Frontiers in Cell and Developmental Biology

192 views

Original Research

Accepted on 13 Feb 2026

A base editing resource for functional annotation of DNA repair variants in breast-derived cell models

in Cancer Cell Biology

Giuseppe Leuzzi
Raquel Cuella-Martin
Samuel B. Hayward
Vincent Chapdelaine-Trépanier
Wei He
Han Xu
Alberto Ciccia

Frontiers in Cell and Developmental Biology

Review

Published on 13 Feb 2026

Obstructive sleep apnea and lung cancer: molecular underpinnings and clinical translational prospects

in Cancer Cell Biology

Lin Zhang
Fengling Liu
Junyao Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1764594

292 views

Review

Published on 13 Feb 2026

BCAAs and related metabolic enzymes: partners in crime driving tumor development

in Cancer Cell Biology

Binfan He
Lingxi Li
Ye Liu
Mengmeng Hao
Ling Zhang
Rongzhang He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1748587

243 views

Review

Accepted on 12 Feb 2026

PI3K/Akt/mTOR signaling as a novel modulator of ABC transporters: Cutting-Edge Approaches to Mitigate Cancer Drug Resistance

in Cancer Cell Biology

Xiaonuo Jia
Donghui Kong
Tinglan Jin
Xiangyu Zhu
Jinghui Bai

Frontiers in Cell and Developmental Biology

103 views

Review

Accepted on 12 Feb 2026

The Neural Niche in Cancer: Mechanistic Insights into Tumor–Neuron–Immune Crosstalk and Therapeutic Opportunities

in Cancer Cell Biology

Hasan Korkaya
Nese Ayşit
Esra Altintas
Fulya Koksalar Alkan
Gurkan Ozturk

Frontiers in Cell and Developmental Biology

180 views

Review

Published on 11 Feb 2026

Senescence-associated and immune-related 9p21.3 locus genes in colorectal cancer: epigenetic architecture, molecular landscape and therapeutic possibilities

in Cancer Cell Biology

Darya A. Lisitsa
Vadim V. Shindyapin
Artem R. Nurislamov
Oleg N. Demidov
Daria A. Bogdanova

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1741704

514 views

Review

Accepted on 09 Feb 2026

The Role of Gut Microbiota and its metabolites in Preventing Oncogenesis

in Cancer Cell Biology

Zehua Li
Jiaxi Yan
Ziyi Zeng
Linyong Zhao

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 06 Feb 2026

Development and Clinical Validation of a Nursing Risk Prediction Model for Chemotherapy-Induced Febrile Neutropenia in Patients with Cancer

in Cancer Cell Biology

Fang Xie
Dongmei Zheng
Na Chen
Jie Zhang
Nan Wang
Qin Yi
Lihuai Wang

Frontiers in Cell and Developmental Biology

163 views

Review

Accepted on 06 Feb 2026

H19 and IGF2 Imprinting from Embryogenesis to Oncogenesis

in Cancer Cell Biology

Bella Ortega*
Rida Saeed*
Sloan White*
Patrick Tajanlangit*
G. Ian Gallicano

Frontiers in Cell and Developmental Biology

427 views

Original Research

Accepted on 05 Feb 2026

A novel kinase inhibitor, Regorafenib, blocks EGFR-dependent signaling to repress tumour metastasis in human triple-negative breast cancers

in Cancer Cell Biology

Ying Liu
Ludong Zhao
Chunxin Wang
Yanzhi Wang
Meijing Liu
Hongyu Du
Xiaohui Chu
Wenqiang Yang
Guan Wang
Bo Zhang

Frontiers in Cell and Developmental Biology

211 views

Review

Published on 05 Feb 2026

WWC proteins as emerging biomarkers and therapeutic targets in cancer pathogenesis

in Cancer Cell Biology

Shuge Wang
Junzhe Li
Xianhua Xu
Shijie Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1712319

450 views

Original Research

Published on 05 Feb 2026

Differential responses to the combination of navitoclax and venetoclax with doxorubicin in murine models of triple negative breast cancer

in Cancer Cell Biology

Homood M. As Sobeai
Abdulrahman M. Alanazi
Faisal Alotaibi
Ali Alhoshani
Khalid Alhazzani
Mashal M. Almutairi
Sultan Almudimeegh
Basel K. Al-Ramadi
Eesha Chakraborty
Tareq Saleh

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1661424

712 views

Original Research

Accepted on 04 Feb 2026

Tumour suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression of diverse biological processes in lung cancer

in Cancer Cell Biology

Mohammed Bourouh
Jinhong Kim
Paola A Marignani

Frontiers in Cell and Developmental Biology

139 views

Review

Published on 04 Feb 2026

Branched-chain amino acid transaminases as promising targets in tumor therapy

in Cancer Cell Biology

Weiran Zhang
Jie Shen
Xuanyin Ding
Hele Liu
Xu Wang
Dan Feng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1712076

436 views

Editorial

Published on 04 Feb 2026

Editorial: Application of novel biomarkers and natural compounds in precision oncology

in Cancer Cell Biology

Yuqing Li
Meng Zhang
Zhao Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1783190

403 views

Original Research

Accepted on 02 Feb 2026

FAM-related prognostic molecular subtypes screening identified epithelial-derived MAOA inhibiting bladder cancer

in Cancer Cell Biology

Hui Yu
雷庆强雷庆强
Wenyong Yang
Min Cao
Miaoyu Zhang
Taisong Wang
Junhao Dong
Xuerui Chen
Xu Su
Yi Huang

Frontiers in Cell and Developmental Biology

141 views

794 articles

articles

Pharmacological inhibition of frizzled 4 delays cell cycle progression and limits oral squamous cell carcinoma growth

Single-cell atlas reveals a pro-metastatic RELB+ neutrophil-myeloid subset underlying lymph node metastasis in EGFR-wildtype LUAD

A putative prognostic model for lung adenocarcinoma based on crotonylation-related genes by bioinformatics and experimental verification

PRMT5 Inhibition Triggers Functional ATM Deficiency and Sensitizes Pancreatic Cancer to CHK1 Blockade

Cancer-associated fibroblast heterogeneity and its role in reshaping immunotherapy in solid cancers: potential strategies and clinical promise

From Mono-to Multi-Cellular In Vitro Models: Reconstructing Colorectal Cancer Complexity for Translational and Personalized Applications

Paeonol inhibits the development of oral squamous cell carcinoma through the PI3K/AKT signaling pathway

Vascular endothelial cells as putative signaling niches for epithelial skin stem cells

A base editing resource for functional annotation of DNA repair variants in breast-derived cell models

Obstructive sleep apnea and lung cancer: molecular underpinnings and clinical translational prospects

BCAAs and related metabolic enzymes: partners in crime driving tumor development

PI3K/Akt/mTOR signaling as a novel modulator of ABC transporters: Cutting-Edge Approaches to Mitigate Cancer Drug Resistance

The Neural Niche in Cancer: Mechanistic Insights into Tumor–Neuron–Immune Crosstalk and Therapeutic Opportunities

Senescence-associated and immune-related 9p21.3 locus genes in colorectal cancer: epigenetic architecture, molecular landscape and therapeutic possibilities

The Role of Gut Microbiota and its metabolites in Preventing Oncogenesis

Development and Clinical Validation of a Nursing Risk Prediction Model for Chemotherapy-Induced Febrile Neutropenia in Patients with Cancer

H19 and IGF2 Imprinting from Embryogenesis to Oncogenesis

A novel kinase inhibitor, Regorafenib, blocks EGFR-dependent signaling to repress tumour metastasis in human triple-negative breast cancers

WWC proteins as emerging biomarkers and therapeutic targets in cancer pathogenesis

Differential responses to the combination of navitoclax and venetoclax with doxorubicin in murine models of triple negative breast cancer

Tumour suppressors LKB1 and SMARCA4 functionally interact to regulate gene expression of diverse biological processes in lung cancer

Branched-chain amino acid transaminases as promising targets in tumor therapy

Editorial: Application of novel biomarkers and natural compounds in precision oncology

FAM-related prognostic molecular subtypes screening identified epithelial-derived MAOA inhibiting bladder cancer