Frontiers in Cell and Developmental Biology

Review

Published on 06 Jan 2026

Construction and application of pancreatic exocrine organoid and spheroid for drug screening and precision medicine

in Cancer Cell Biology

Xin Tan
Bangwei Huang
Xinyi Yang
Pengyuan Wang
Lianghao Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746622

261 views

Original Research

Accepted on 05 Jan 2026

Effectiveness Comparison of Domestic versus Imported Immune Checkpoint Inhibitors in Neoadjuvant Chemoimmunotherapy for Esophageal Squamous Cell Carcinoma

in Cancer Cell Biology

Mingduan Chen
Shuhan Xie
Zhinuan Hong
Mingqiang Kang

Frontiers in Cell and Developmental Biology

Review

Accepted on 05 Jan 2026

The Proteostasis Paradox: From Systemic Collapse in Aging to Pathway-Specific Addiction in Prostate Cancer

in Cancer Cell Biology

Danhong Guo
Yaoyao Peng
Yanlan Yu

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 05 Jan 2026

Differential Responses to the Combination of Navitoclax and Venetoclax with Doxorubicin in Murine Models of Triple Negative Breast Cancer

in Cancer Cell Biology

Homood As Sobeai
Abdulrahman M Alanazi
Faisal Alotaibi
Ali Alhoshani
Khalid Alhazzani
Mashal Almutairi
Basel K Al-Ramadi
Eesha Chakraborty
Tareq Saleh
David A Gewirtz

Frontiers in Cell and Developmental Biology

Review

Published on 05 Jan 2026

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition

in Cancer Cell Biology

Fabio Giuntini
Jonathan R. Whitfield
Daniel Massó-Vallés
Laura Soucek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1726515

363 views

Original Research

Published on 05 Jan 2026

A novel protein encoded by circIMP3 promotes prostate cancer progression by regulating alternative splicing and tumor microenvironment

in Cancer Cell Biology

Wenren Zuo
Weizhou Huang
Haojie Chen
Yan Xu
Yang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722674

300 views

Original Research

Accepted on 02 Jan 2026

Breast cancer bone metastasis and bone metastatic cells retain NKG2DLs intracellularly: could this be a strategy to evade immune recognition?

in Cancer Cell Biology

Marta Gomarasca
Paola Maroni
Chiara Verdelli
Laura Gerosa
Martina Faraldi
Alessandro Luzzati
Luca Cannavò
Giuseppe Banfi
Giovanni Lombardi

Frontiers in Cell and Developmental Biology

Review

Published on 02 Jan 2026

The transcribed ultraconserved regions: emerging players in colorectal cancer biology and therapy

in Cancer Cell Biology

Yi Zhang
Zichen Wei
Xin Wang
Pan Wang
Lei Pang
Hongliang Dong
Han Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1599891

318 views

Editorial

Accepted on 30 Dec 2025

Editorial: Cuproptosis and Tumors, Volume II: From Basic Research to Clinical Translation

in Cancer Cell Biology

Bing Liu
Jiannan Liu
Guojun Chen
Xu Chun
Lin-Lin Bu

Frontiers in Cell and Developmental Biology

114 views

Mini Review

Accepted on 29 Dec 2025

Mitochondrial epigenetic mechanisms in cancer: an updated overview

in Cancer Cell Biology

Andrea Stoccoro
Fabio Coppedè

Frontiers in Cell and Developmental Biology

239 views

Mini Review

Accepted on 29 Dec 2025

The Fall of the Genome Protectors Triad: PBRM1, SETD2, and BAP1's Impact on Metabolism and Immunity in Clear Cell Renal Cell Carcinoma

in Cancer Cell Biology

Mathieu Johnson
Sandra Turcotte

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 29 Dec 2025

Integrative Analysis of EMT-Driving Genes Identifies a Prognostic Signature and GJB2 as a Potential Biomarker in Glioblastoma

in Cancer Cell Biology

Xiao-fei Liu
Bing Wang
Min Zhou
Duo Gong
Jia-hui Zhang
Jun-yan He
Wentao Xiao

Frontiers in Cell and Developmental Biology

Review

Accepted on 29 Dec 2025

Gastric Cancer Organoids: A Promising model for Personalized Treatment of Gastric Cancer

in Cancer Cell Biology

Yu Chang
Yunfeng Hu

Frontiers in Cell and Developmental Biology

119 views

Review

Accepted on 26 Dec 2025

Research Advances on the Risk of Prostate Cancer from Phthalates Exposure: From Epidemiological Evidence to Multidimensional Prevention and Control

in Cancer Cell Biology

Binbin Wang
Hongliang Cao
Shuxin Li
Zhijun Tang
Gengchen Huang
Zhanhao Li
Yutao Ma
Wei Wei
Mo Chen

Frontiers in Cell and Developmental Biology

105 views

Original Research

Accepted on 26 Dec 2025

STC2 promotes anoikis resistance by modulating TGIF1 mRNA stability in colorectal cancer

in Cancer Cell Biology

Fan Hu
Qiuming He
Jie Cheng
Jun Lin

Frontiers in Cell and Developmental Biology

137 views

Original Research

Accepted on 18 Dec 2025

A multi-omics features-based approach integrating immunogenicity and inflammation enhances immunotherapy benefit in clear cell renal cell carcinoma

in Cancer Cell Biology

Yanfeng Xue
Feng Han
Shuqing Wei
Yiqun Zhang
Nan Wang
Ling Liu
Zhen Chen
Zhihua Pei
Hailong Hao

Frontiers in Cell and Developmental Biology

306 views

Mini Review

Published on 18 Dec 2025

METTL5 in physiology and pathology: mechanisms and implications

in Cancer Cell Biology

Chunhong Li
Xiulin Jiang
Yixiao Yuan
Qiang Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1708541

565 views

Mini Review

Published on 18 Dec 2025

Metabolic reprogramming in bone metastasis of human cancers

in Cancer Cell Biology

Tianda Li
Ziyi Wang
Haitao Yang
Yihan Kang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1711592

667 views

Original Research

Accepted on 17 Dec 2025

CGR11 Promotes Hepatocellular Carcinoma Progression by Regulating Autophagy through the PI3K/AKT Pathway

in Cancer Cell Biology

Jia Zhou
Sulai Liu
Yinghui Song
Junjie Liu
Zhiguo Tan
Jie Liu
Xiaoxia Han
Yang Xing
Xinrun Wang
Chuang Peng

Frontiers in Cell and Developmental Biology

181 views

Review

Accepted on 16 Dec 2025

Exosomes in early lung cancer diagnostics: the current state of progress made and prospects

in Cancer Cell Biology

Xiaotian Liu
Xianlin Xu
Qian Wang

Frontiers in Cell and Developmental Biology

178 views

Review

Published on 16 Dec 2025

Endoplasmic reticulum stress in non-small cell lung cancer: a review of therapeutic agents, mechanistic insights, and implications for therapy

in Cancer Cell Biology

Qiong Luo
Xinxin Gao
Peng Meng
Xiao Qi
Wen Wang
Shan Li
Linlin Duan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693023

950 views

Review

Published on 16 Dec 2025

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

in Cancer Cell Biology

Qiwei Liu
Zhiyu Xie
Wei Li
Mengxiang Li
Yijun Qi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1714824

748 views

Original Research

Accepted on 15 Dec 2025

Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma

in Cancer Cell Biology

Ruolian Gao
Lili Mi
Jianfei Shi
Meng Zhang
Xiaoling Duan
Man zhao
Fei Yin

Frontiers in Cell and Developmental Biology

138 views

Original Research

Accepted on 15 Dec 2025

PTEN enhances the radiosensitivity of melanoma by inhibiting DNA-PKcs

in Cancer Cell Biology

Shengqian Zhu
Haitao Xu
Fu Shen
Fangying Chen
Yangjian Wang

Frontiers in Cell and Developmental Biology

205 views

759 articles

articles

Construction and application of pancreatic exocrine organoid and spheroid for drug screening and precision medicine

Effectiveness Comparison of Domestic versus Imported Immune Checkpoint Inhibitors in Neoadjuvant Chemoimmunotherapy for Esophageal Squamous Cell Carcinoma

The Proteostasis Paradox: From Systemic Collapse in Aging to Pathway-Specific Addiction in Prostate Cancer

Differential Responses to the Combination of Navitoclax and Venetoclax with Doxorubicin in Murine Models of Triple Negative Breast Cancer

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition

A novel protein encoded by circIMP3 promotes prostate cancer progression by regulating alternative splicing and tumor microenvironment

Breast cancer bone metastasis and bone metastatic cells retain NKG2DLs intracellularly: could this be a strategy to evade immune recognition?

The transcribed ultraconserved regions: emerging players in colorectal cancer biology and therapy

Editorial: Cuproptosis and Tumors, Volume II: From Basic Research to Clinical Translation

Mitochondrial epigenetic mechanisms in cancer: an updated overview

The Fall of the Genome Protectors Triad: PBRM1, SETD2, and BAP1's Impact on Metabolism and Immunity in Clear Cell Renal Cell Carcinoma

Integrative Analysis of EMT-Driving Genes Identifies a Prognostic Signature and GJB2 as a Potential Biomarker in Glioblastoma

Gastric Cancer Organoids: A Promising model for Personalized Treatment of Gastric Cancer

Research Advances on the Risk of Prostate Cancer from Phthalates Exposure: From Epidemiological Evidence to Multidimensional Prevention and Control

STC2 promotes anoikis resistance by modulating TGIF1 mRNA stability in colorectal cancer

A multi-omics features-based approach integrating immunogenicity and inflammation enhances immunotherapy benefit in clear cell renal cell carcinoma

METTL5 in physiology and pathology: mechanisms and implications

Metabolic reprogramming in bone metastasis of human cancers

CGR11 Promotes Hepatocellular Carcinoma Progression by Regulating Autophagy through the PI3K/AKT Pathway

Exosomes in early lung cancer diagnostics: the current state of progress made and prospects

Endoplasmic reticulum stress in non-small cell lung cancer: a review of therapeutic agents, mechanistic insights, and implications for therapy

Aging-associated mechanisms and metabolic vulnerabilities in esophageal carcinoma: an integrative review

Exosome-related immune signatures and peripheral blood assays predict prognosis and immunotherapy response in hepatocellular carcinoma

PTEN enhances the radiosensitivity of melanoma by inhibiting DNA-PKcs