Frontiers in Cell and Developmental Biology | Molecular and Cellular Reproduction

Original Research

Accepted on 17 Sep 2025

Spatial metabolomics and transcriptomics reveal cell type-specific dynamics in the placenta of patients with late-onset preeclampsia

in Molecular and Cellular Reproduction

Xiaowei Wei
Qian Li
Chuanmei Qin
Weihong Zeng
Yuxu Liu
Jiawei Lu
Jiuming He
cailian chen
Xiaoqing Zhang
Yi Lin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1659880

179 views

Original Research

Accepted on 16 Sep 2025

L-cysteine Mitigates Busulfan-Induced Testicular Injury through Modulation of CBS/H2S Axis

in Molecular and Cellular Reproduction

Song Liu
Bin Wei
Huijun Yang
Han Wei
Anran Xu
Lianbing Sheng
Xiangyang Sun
Yunling Dong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1679330

134 views

Original Research

Accepted on 08 Sep 2025

Functional Characterization and Phenotyping of RAB2A and Lactadherin/MFGE8 as Boar Sperm Zona Pellucida Binding Proteins

in Molecular and Cellular Reproduction

Natálie Zelenková
Veronika Kraus
Lukas Ded
Daniela Spevakova
Lucie Sadílková
Michaela Frolikova
Aneta Pilsova
Zuzana Pilsová
Barbora Klusackova
Ondřej Šimoník

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1653053

477 views

Review

Accepted on 04 Sep 2025

Cracking the Code: How piRNA Pathway Shapes Spermatogenesis and Combats Male Infertility

in Molecular and Cellular Reproduction

Zhidan Hong
Sihan Huang
Li Li
Ying Gao
Binyu Ma
Qigang Fan
Yuanzhen Zhang
Mei Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1657744

640 views

Editorial

Published on 01 Sep 2025

Editorial: Sperm epigenetic code: implications in reproductive health and paternal contribution to embryo development

in Molecular and Cellular Reproduction

Marta Lombò
Gilda Cobellis
Francesco Manfrevola

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1666435

926 views

Original Research

Published on 29 Aug 2025

Integrating microarray data and single-cell RNA-seq reveals correlation between kit and nmyc in mouse spermatogonia stem cell population

in Molecular and Cellular Reproduction

Danial Hashemi Karoii
Hossein Azizi
Thomas Skutella

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1634347

1,285 views

Original Research

Published on 29 Aug 2025

High-glucose diets differentially modulate phosphatidylcholine metabolism and fecundity in Caenorhabditis elegans

in Molecular and Cellular Reproduction

Chao-Wen Wang
Phebe Chiu
Sophia Monsalve
Ricardo Roure
Xiaofei Bai
Jia-Jin Law
Yu-Ching Wu
Yet-Ran Chen
You-Liang Cheng
Rey-Huei Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622695

1,248 views

Review

Published on 29 Aug 2025

Exploring the protective effects of coenzyme Q10 on female fertility

in Molecular and Cellular Reproduction

Yu Jiang
Yao Han
Pengyun Qiao
Fa Ren

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633166

2,212 views

Original Research

Published on 29 Aug 2025

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation

in Molecular and Cellular Reproduction

Veronica Porreca
Teresa Chioccarelli
Francesco Albano
Valeria Nittoli
Giulia Ricci
Concetta Ambrosino
Rosanna Chianese
Vincenza Grazia Mele
Antonella Migliaccio
Mariano Stornaiuolo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1524919

631 views

Mini Review

Accepted on 27 Aug 2025

Metabolic State and Female Fertility in ART Cycles: A Summary of Current Advances

in Molecular and Cellular Reproduction

Natascha Berger
Katharina Brugger
Herbert Fluhr

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1645127

571 views

Review

Accepted on 25 Aug 2025

From Biomolecules to Breakthroughs: Exosomes as Next-Generation Theranostics in Female Infertility

in Molecular and Cellular Reproduction

AHMED A. ALDARMAHI
Shifan Khanday
Ehab S Taher
Ahmed Abdeen
Gamal Atia
Dania A Mohammed
Dina S Nasr
Rayan Albarakati
Donia E Zaghamir
Helal F Hetta

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1605174

766 views

Review

Published on 22 Aug 2025

The role of amniotic epithelial cells in preterm birth: mechanisms and clinical implications

in Molecular and Cellular Reproduction

Lulu Meng
Jing Yang
Yijie Gao
Yiran Xie
Miaomiao Chen
Wangping Hao
Yi Luo
Ping Ru
Ling Wang
Zhiying He

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1590212

1,058 views

Review

Published on 22 Aug 2025

Microbial metabolites short chain fatty acids, tight junction, gap junction, and reproduction: a review

in Molecular and Cellular Reproduction

Lulu Fu
Min Wang
Dan Li
Shuai Ma
Fuliang Zhang
Lianwen Zheng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1624415

1,116 views

Original Research

Published on 18 Aug 2025

Aquaporin 2 is differentially expressed in granulosa cells of various stages of human follicles and is regulated by luteinizing hormone

in Molecular and Cellular Reproduction

Zetong Zheng
Jifan Tan
Minghui Chen
Xiubing Zhang
Simin Liu
Yangxing Wen
Lingli Long
Canquan Zhou
Yubin Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1647476

901 views

Original Research

Published on 08 Aug 2025

MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint

in Molecular and Cellular Reproduction

Dandan Zhang
Zaishan Yang
Yongteng Zhang
Fugui Fang
Hongguo Cao
Yunsheng Li
Zubing Cao
Yanfeng Xue
Mianqun Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1635110

821 views

Original Research

Published on 04 Aug 2025

Spatial transcriptomics reveals Inhba/Smad2/E2f4 axis in Lrp2high thecal cell proliferation in androgen-induced PCOS mice

in Molecular and Cellular Reproduction

Man Luo
Xiaona Tian
Li Li
Guomei Zhang
Wenzhi Liu
Linlin Mei
Haoran Li
Xiaoyan You
Dongmei Zhang
Mengsi Zhou

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1633254

1,527 views