Frontiers in Cell and Developmental Biology

Original Research

Published on 27 May 2025

Mesenchymal stem cell-derived exosome subpopulations remained consistent for 28 culture days, displaying therapeutic effects in a silicosis mouse model

in Stem Cell Research

Lina Zhang
Jing Jin
Liguang Sun
Gang Hou
Mingming Deng
Yiding Bian
Jianming Liu
Wei Cheng
Shaoliang Xing
Wenjia Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1550447

588 views

Brief Research Report

Published on 21 May 2025

Synchrotron radiation FTIR microspectroscopy enables measuring dynamic cell identity patterning during human 3D differentiation

in Stem Cell Research

Tanja Dučić
Francisco Rodriguez-Yañez
Elena Gonzalez-Muñoz

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1569187

728 views

Editorial

Published on 16 May 2025

Editorial: Senescence and reprogramming: hallmarks in aging and disease

in Stem Cell Research

F. Javier González-Rico
Jiyue Zhu
Guangyong Peng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1622682

730 views

Original Research

Published on 16 May 2025

Optimal Sca-1-based procedure for purifying mouse adipose-derived mesenchymal stem cells with enhanced proliferative and differentiation potential

in Stem Cell Research

Xingyu Tao
Jialian Wang
Yuan Yan
Peifeng Cheng
Bin Liu
Huimin Du
Bailin Niu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566670

877 views

Original Research

Accepted on 15 May 2025

Comparative analysis of small molecule and growth factor-derived human induced pluripotent stem cell-derived hepatocyte-like cells

in Stem Cell Research

Faizal Asumda
Shadia Alzoubi
Kiyasha Padarath
Kimya Jones
Ravindra Kolhe
Ashis Kumar Mondal
Ahmet Alptekin
Wenbo Zhi
Tae Jin Lee
Robert Huebert

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1594340

251 views

Original Research

Published on 15 May 2025

Optimizing single cell RNA sequencing of stem cells. A streamlined workflow for enhanced sensitivity and reproducibility in hematopoietic studies. The use of human umbilical cord blood-derived hematopoietic stem and progenitor cells

in Stem Cell Research

Justyna Jarczak
Patrycja Kieszek
Mariusz Z. Ratajczak
Magdalena Kucia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1590889

724 views

Original Research

Published on 13 May 2025

Revolutionizing bone regeneration and wound healing: Mechanical stromal vascular fraction and hyaluronic acid in a mouse calvarial defect model

in Stem Cell Research

Riccardo Ossanna
Lindsey Alejandra Quintero Sierra
Sara Ghazanfar Tehrani
Vivekanand Jha
Chiara Curatola
Alice Busato
Anita Conti
Giamaica Conti
Nicola Zingaretti
Pier Camillo Parodi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582083

1,078 views

Original Research

Published on 09 May 2025

Characterization and neurogenic responses of primary and immortalized Müller glia

in Stem Cell Research

Thi-Hang Tran
Donny Lukmanto
Mei Chen
Olaf Strauß
Toshiharu Yamashita
Osamu Ohneda
Shinichi Fukuda

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1513163

763 views

Review

Published on 08 May 2025

A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications

in Stem Cell Research

Margarita Matiukhova
Anastasia Ryapolova
Vladimir Andriianov
Vasiliy Reshetnikov
Sophia Zhuravleva
Roman Ivanov
Alexander Karabelsky
Ekaterina Minskaia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593207

1,640 views

Original Research

Published on 08 May 2025

In vivo and in vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment

in Stem Cell Research

Abdulrahman Johor
A. S. M. Mahadiuzzaman
Abdulaziz Abdullah Alqusayer
Saleh Abdulaziz Alkarim
F. A. Dain Md Opo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521809

1,151 views

Original Research

Published on 06 May 2025

Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems

in Stem Cell Research

Kosuke Sakaguchi
Chiemi Kimura-Nakajima
Akihiko Inaba
Yoshiko Hatano
Hanako Ogawa
Yuichi Koshiishi
Keisuke Tanaka
Tatsuya Kometani
Makoto Ohmoto
Koji Sato

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593226

1,526 views

Brief Research Report

Published on 30 Apr 2025

Using a brain-like endothelial cell differentiation to characterize the CS79iBRCA-n2 BRCA1 mutated patient derived stem cell line

in Stem Cell Research

Natalie G. Alexander
Kylie A. Buchanan
Alexandra E. Meyer
Lauren M. Mitterway
Caroline O. Vanderburgh
Shreyas S. Rao
Brandon J. Kim

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1516669

1,203 views

Review

Published on 30 Apr 2025

Challenges of in vitro modelling of liver fibrosis

in Stem Cell Research

Patricia Ros-Tarraga
Estela Villanueva-Badenas
Estela Sanchez-Gonzalez
Gloria Gallego-Ferrer
M. Teresa Donato
Laia Tolosa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1567916

1,090 views

Original Research

Published on 29 Apr 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

in Stem Cell Research

Cécile Méjécase
Ya Zhou
Nicholas Owen
Pablo Soro-Barrio
Riccardo Cheloni
Neelima Nair
Hajrah Sarkar
Lyes Toualbi
Mariya Moosajee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511066

1,407 views

Original Research

Published on 29 Apr 2025

Mitochondria-derived reactive oxygen species induce over-differentiation of neural stem/progenitor cells after non-cytotoxic cisplatin exposure

in Stem Cell Research

Felipe A. Bustamante-Barrientos
Eliana Lara-Barba
Yeimi Herrera-Luna
Cynthia García-Guerrero
Eduardo Silva-Pavez
Jonathan Morales-Reyes
María Jesús Araya
Liliana Yanten-Fuentes
Noymar Luque-Campos
Claudia Altamirano

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1555153

1,477 views

Original Research

Published on 24 Apr 2025

TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation in vitro

in Stem Cell Research

Arim Shin
Sung Ah Park
Ji Yeon Kim
Eun Jung Baek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1474631

1,063 views