volumes

Volume 13 - 2025

Original Research

Published on 07 Jan 2026

Deciphering the immunomodulatory mechanisms of Periplaneta americana L. extract CII-3: insight from integrated metabolomics and network pharmacology

Yilin Wang
Yingxiang Wu
Xi Liu
Zhiyan Lu
Tianqian Li
Yang Jin
Yan Wang
Jiali Zhu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718560

861 views

Review

Published on 07 Jan 2026

The role of ANLN in malignant tumors: pathogenesis, treatment resistance and targeted strategies

YiXuan Wang
Yang Xiao
JieLin Yu
YuanHua Zou
Zhe Wang
XiangHong Yang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1739855

707 views

Mini Review

Published on 06 Jan 2026

Mesenchymal stem cell-based therapy for osteoarthritis: a systematic review and meta-analysis of clinical outcomes and functional recovery

Jincheng Wang
Hao Xue
Mingfei Shi
Renshou Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746471

1,681 views

Mini Review

Published on 06 Jan 2026

A primer on tRNAs, tRNA-m1A58 modification, and tRNA derivatives in T-cell activation

Chuanxiang Zhao
Juxiang Shen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1683213

742 views

Review

Published on 06 Jan 2026

Construction and application of pancreatic exocrine organoid and spheroid for drug screening and precision medicine

Xin Tan
Bangwei Huang
Xinyi Yang
Pengyuan Wang
Lianghao Hu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746622

903 views

Original Research

Published on 06 Jan 2026

Macrophage-myofibroblast transition as a novel therapeutic target in shoulder stiffness: multi-omics study and experimental validation

Beijie Qi
Weihan Yu
Hanyi Wang
Yuqi Li
Shuang Deng
Chengqing Yi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1727624

595 views

Review

Published on 06 Jan 2026

Brain-derived extracellular vesicles potentially mediate crosstalk with peripheral organs in neurodegenerative diseases

Ramzi H. Hamdalla
Vibha B. Bhaskar
Changhai Tian

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1710150

1,378 views

Review

Published on 06 Jan 2026

Neoantigens in cancer immunoediting: from mechanisms to personalized vaccines in breast cancer

Shiyan Zeng
Li Wang
Wanqin Zeng
Lei Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1733549

1,411 views

Original Research

Published on 06 Jan 2026

Evidence for KISS-1 nuclear translocation and PI3K/AKT signaling in the ultrastructurally and morphometrically analyzed human endometriosis

Rasim Hamutoğlu
Celal Kaloğlu
Hüseyin Eray Bulut
Çağlar Yıldız

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1625031

992 views

Original Research

Published on 05 Jan 2026

Epigenetic, histological and clinical characterization of preeclampsia in oocyte donation pregnancies: insights into immune dysregulation and microRNA-mediated pathways

Irma Saulle
Maria Di Giminiani
Ozge Yazici
Claudio Fenizia
Manuela Nebuloni
Roberta Rossi
Mara Biasin
Valeria Savasi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1718305

905 views

Original Research

Published on 05 Jan 2026

Kv2.1 negatively regulates Reissner fiber development

R. Rosa Amini
Ruchi P. Jain
Justyna Jędrychowska
Vladimir Korzh

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720752

1,117 views

Review

Published on 05 Jan 2026

AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response

Minglei Liu
Yichuan Zhou
Xiaohan Mei
Zehao Yu
Boyun Guan
Yi Xiao
Shixian Liu
Hao Wang
Yanguo Qin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1755565

1,418 views

Review

Published on 05 Jan 2026

Modeling human placental biology: a review of organoid technologies

Alaijah Bashi
Tyana Joseph
Viviane Schuch
Erica L. Johnson

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1693923

1,201 views
1 citation

Review

Published on 05 Jan 2026

Embryo-secreted microRNAs enable non-invasive assessment of chromosomal status and viability in in vitro fertilization

Masoumeh Esmaeilivand
Mohammad Hossein Nasr-Esfahani

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1747211

837 views

Review

Published on 05 Jan 2026

The leading role of MYC in DNA damage response: exploring opportunities for therapeutic inhibition

Fabio Giuntini
Jonathan R. Whitfield
Daniel Massó-Vallés
Laura Soucek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1726515

1,367 views

Original Research

Published on 05 Jan 2026

The predictive value of necroptosis-related lncRNAs in prostate cancer prognosis and their potential to distinguish between cold and hot tumors

Ke Zhang
Kai Li
Junpeng Deng
Chunchun Zhao
Fei Wang
JianJun Xie

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722671

771 views

Original Research

Published on 05 Jan 2026

Mandibular extracellular vesicles mediate morphogenesis and mineralization of tooth germs in miniature swine through the miR-206/HDAC4 signaling axis

Xiaoyu Cao
Duanlin Ma
Yujiao Song
Yiping Gao
Wen Liu
Xiaohong Du
Xiaojun Sun

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1707072

1,027 views

Review

Published on 05 Jan 2026

The varied functions of the giant muscle scaffold protein obscurin

James Novac Di Paola
Frieder Schöck

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1689326

1,010 views

Original Research

Published on 05 Jan 2026

A novel protein encoded by circIMP3 promotes prostate cancer progression by regulating alternative splicing and tumor microenvironment

Wenren Zuo
Weizhou Huang
Haojie Chen
Yan Xu
Yang Zhang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1722674

1,089 views

Review

Published on 02 Jan 2026

The transcribed ultraconserved regions: emerging players in colorectal cancer biology and therapy

Yi Zhang
Zichen Wei
Xin Wang
Pan Wang
Lei Pang
Hongliang Dong
Han Xu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1599891

906 views

Original Research

Published on 02 Jan 2026

Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate

Chunhao Deng
Zhaoying Zhang
Xia Xiao
Carlos Godoy-Parejo
Faxiang Xu
Chengcheng Song
Huanyi Lin
Qinru Li
Shicai Fang
Weiwei Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1696372

926 views

Volume 14 - 2026

Original Research

Accepted on 06 Jan 2026

The Actin Regulator DBNL Is a Critical Mediator of Sympathetic Stress-Induced Bone Loss

Qin Yin
Jun Gu
Ruijun Bai
Kai Zhao
Qiubo Wang
Yu Liu
Haifeng Li

Frontiers in Cell and Developmental Biology

210 views

Original Research

Accepted on 06 Jan 2026

Multi-omics analysis reveals IGF1 as a central regulator of Sertoli cell proliferation and metabolic reprogramming in Tibetan sheep

Huihui Wang
Xujie Li
Xingcai Qi
Xiaodan Shi
Baoqi He
Chen Haolin
Youji Ma
Taotao Li

Frontiers in Cell and Developmental Biology

176 views

Original Research

Accepted on 05 Jan 2026

Effectiveness Comparison of Domestic versus Imported Immune Checkpoint Inhibitors in Neoadjuvant Chemoimmunotherapy for Esophageal Squamous Cell Carcinoma

Mingduan Chen
Shuhan Xie
Zhinuan Hong
Mingqiang Kang

Frontiers in Cell and Developmental Biology

245 views