ORIGINAL RESEARCH article
Front. Cell. Infect. Microbiol.
Sec. Clinical Infectious Diseases
Volume 15 - 2025 | doi: 10.3389/fcimb.2025.1590220
This article is part of the Research TopicExploring Clinical Application Scenarios of Metagenomic Next-Generation Sequencing for Pathogen DiagnosisView all 3 articles
Rapidly Progressive Pulmonary Abscess Initially Misdiagnosed as Lung Cancer: The Role of Peptostreptococcus stomatis and Parvimonas micra
Provisionally accepted
- Bishan hospital of Chongqing Medical University, Chongqing, China
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Pulmonary abscess is a serious infectious disease characterized by localized lung tissue necrosis, primarily caused by anaerobic or facultative anaerobic bacterial infections. While the Streptococcus anginosus group (SAG) is a well-established pathogen in pulmonary abscess formation, recent findings suggest that strict anaerobes such as Peptostreptococcus stomatis and Parvimonas micra can also contribute to deep-seated infections. However, their role in rapidly progressive pulmonary abscesses has not been previously documented.Here, we present a case of a rapidly progressive pulmonary abscess caused by Peptostreptococcus stomatis and Parvimonas micra in an immunocompetent patient, initially misdiagnosed as lung cancer. This case highlights the importance of differentiating infectious lung lesions from malignancies and underscores the clinical utility of metagenomic next-generation sequencing (mNGS) in diagnosing rare anaerobic infections, offering valuable insights for precise diagnostic and therapeutic strategies.
Keywords: Pulmonary abscess, Immunocompetent patient, Peptostreptococcus stomatis, Parvimonas micra, Rapidly progressive infection
Received: 09 Mar 2025; Accepted: 28 May 2025.
Copyright: © 2025 Hu, Li, Jin, Liu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Bicui Liu, Bishan hospital of Chongqing Medical University, Chongqing, China
Kaijin Wang, Bishan hospital of Chongqing Medical University, Chongqing, China
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