Exploring Clinical Application Scenarios of Metagenomic Next-Generation Sequencing for Pathogen Diagnosis

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ORIGINAL RESEARCH

Accepted on 13 Oct 2025

Cost-Effectiveness Analysis of Metagenomic Next-Generation Sequencing versus traditional bacterial cultures for Postoperative Central Nervous System Infections in Critical Care settings: A Prospective Pilot Study

Ying Tian
Ningyuan Xu
Yuqing Chen
Zimeng Xu
Jian-Xin Zhou
Linlin Zhang

doi 10.3389/fcimb.2025.1710412

BRIEF RESEARCH REPORT

Accepted on 13 Oct 2025

Anorexia for oily foods as the initial symptom of chlamydia psittaci pneumonia complicated by hepatic dysfunction: a case report

Yajun Xiao
Yu-Yu Zhou
Jie Zhang
Yan-Qun Liu

doi 10.3389/fcimb.2025.1654042

ORIGINAL RESEARCH

Accepted on 01 Oct 2025

Utilization of Cell-Free DNA Metagenomic Analysis for Early Detection and Microbial Identification in Prosthetic Joint Infections: A Prospective Cohort Study in Korea

Jung Ah Lee
Eun Hwa Lee
Dongju Won
Seung-Tae Lee
Kwan Kyu Park
Saeam Shin
Su Jin Jeong

doi 10.3389/fcimb.2025.1663857

177 views

ORIGINAL RESEARCH

Accepted on 01 Oct 2025

Metagenomic Next-Generation Sequencing Facilitates Precision Treatment and Prognostic Improvement in Pulmonary Cryptococcosis

Yapeng Xu
Jingxuan Miao
Jing Chen
Liqun Ye
Yang Kangli
Hongmin Wang

doi 10.3389/fcimb.2025.1638215

143 views

ORIGINAL RESEARCH

Published on 18 Sep 2025

Clinical performance of metagenomic next-generation sequencing for distinction and diagnosis of Mucorales infection and colonization

Xiaoli Zhou
Chenxi Yang
Xin Liu
Jiaqiang Wang
Yanqiao Li
Lingai Pan
Shengkun Peng
Hua Yu
Xiren Deng

doi 10.3389/fcimb.2025.1631960

681 views

ORIGINAL RESEARCH

Published on 18 Sep 2025

The application value of targeted next-generation sequencing in the diagnosis of primary osteoarticular infections: A single-center study

Zhengyong Tao
Mengqi Zhu
Jiandang Shi
Zongqiang Yang
NingKui Niu

doi 10.3389/fcimb.2025.1593228

781 views

BRIEF RESEARCH REPORT

Published on 11 Sep 2025

Optimization of decision thresholds for Mycobacterium tuberculosis can effectively improve the performance of mNGS in tuberculosis diagnosis

Yuecui Li
Lili Zhang
Guannan Ma
Chenghang Li
Weiyue Hu
Ruotong Ren
Yinghui Zang
Dandan Ying
Shuai Qiu
2 more
Xuefang Cao

doi 10.3389/fcimb.2025.1646194

1,078 views

CASE REPORT

Published on 02 Sep 2025

Human cytomegalovirus infection-induced lymphocytosis diagnosed by metagenomic next-generation sequencing: a case report and literature review

Shaofan Zhang
Li Sun
Liman Wang
Yuwei Liu
Gao Tan
Tao Liu
Wen Yang
Xiaoli Liu

doi 10.3389/fimmu.2025.1637085

1,070 views

ORIGINAL RESEARCH

Published on 16 Jun 2025

Infected pericardial effusion caused by Prevotella intermedia: a rare diagnosis

Wan Xu
Dan Han
Tianyang Chen
Qian Wang

doi 10.3389/fcimb.2025.1612282

828 views

ORIGINAL RESEARCH

Published on 11 Jun 2025

Rapidly progressive pulmonary abscess initially misdiagnosed as lung cancer: the role of Peptostreptococcus stomatis and Parvimonas micra

Hang Hu
Kui Li
Zhidong Jin
Kaijin Wang
Bicui Liu

doi 10.3389/fcimb.2025.1590220

1,037 views

ORIGINAL RESEARCH

Published on 09 Jun 2025

Application of targeted next-generation sequencing for pathogens diagnosis and drug resistance prediction in bronchoalveolar lavage fluid of pulmonary infections

Qiugui Xu
Qiumei Chen
Wen Qiu
Lili Liu
Wan Zeng
Jinling Chen
Yangyang Li
Zhen Guo
Ling Rong
2 more
Liye Yang

doi 10.3389/fcimb.2025.1590881

1,688 views
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Frontiers in Cellular and Infection Microbiology

Clinical Infectious Diseases

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Frontiers in Medicine
- Infectious Diseases: Pathogenesis and Therapy
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Articles

Cost-Effectiveness Analysis of Metagenomic Next-Generation Sequencing versus traditional bacterial cultures for Postoperative Central Nervous System Infections in Critical Care settings: A Prospective Pilot Study

Anorexia for oily foods as the initial symptom of chlamydia psittaci pneumonia complicated by hepatic dysfunction: a case report

Utilization of Cell-Free DNA Metagenomic Analysis for Early Detection and Microbial Identification in Prosthetic Joint Infections: A Prospective Cohort Study in Korea

Metagenomic Next-Generation Sequencing Facilitates Precision Treatment and Prognostic Improvement in Pulmonary Cryptococcosis

Clinical performance of metagenomic next-generation sequencing for distinction and diagnosis of Mucorales infection and colonization

The application value of targeted next-generation sequencing in the diagnosis of primary osteoarticular infections: A single-center study

Optimization of decision thresholds for Mycobacterium tuberculosis can effectively improve the performance of mNGS in tuberculosis diagnosis

Human cytomegalovirus infection-induced lymphocytosis diagnosed by metagenomic next-generation sequencing: a case report and literature review

Infected pericardial effusion caused by Prevotella intermedia: a rare diagnosis

Rapidly progressive pulmonary abscess initially misdiagnosed as lung cancer: the role of Peptostreptococcus stomatis and Parvimonas micra

Application of targeted next-generation sequencing for pathogens diagnosis and drug resistance prediction in bronchoalveolar lavage fluid of pulmonary infections

Frontiers in Cellular and Infection Microbiology

Clinical Infectious Diseases

Participating Journals

Frontiers in Medicine

Infectious Diseases: Pathogenesis and Therapy