CORRECTION article

Front. Cell. Infect. Microbiol., 25 July 2025

Sec. Clinical Infectious Diseases

Volume 15 - 2025 | https://doi.org/10.3389/fcimb.2025.1659574

Correction: Evaluation of a novel Aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis

  • YL

    Yajie Lu 1

  • HZ

    Huanhuan Zhong 2,3

  • YW

    Yujie Wang 3

  • CS

    Chao Sun 3

  • YL

    Yuanyuan Li 3

  • YC

    Yuchen Cai 3

  • XC

    Xiaomin Cai 3

  • JW

    Jiamei Wang 4

  • JZ

    Jinjin Zhong 3

  • XS

    Xin Su 1*

  • 1. Department of Respiratory and Critical Care Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China

  • 2. Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Soochow University, Suzhou, China

  • 3. Department of Respiratory and Critical Care Medicine, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China

  • 4. Department of Respiratory and Critical Care Medicine, Nanjing Jinling Hospital, Medical School, Nanjing Medical University, Nanjing, China

The title of this article was erroneously given as: “Evaluation of a novel aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis”. The correct title of the article is “Evaluation of a novel Aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis”.

“Zhu, R. Z., Cheng, J., Luo, Y., Qiu, W., Huang, J., Jiang, Y., et al. (2023b). Diagnostic

laboratory features and performance of an aspergillus IgG lateral flow assay in a chronic

pulmonary aspergillosis cohort. Microbiol. Spectr. 11, e0026423. doi: 10.1128/

spectrum.00264-23]”was not cited in the article. The citation has now been inserted in the page 10, section 4 Discussion, paragraph 5 and should read:

“Zhu, 2023b”

In the Abstract, The mistake was the non-uniform writing of “vs.”. This has been corrected to read: “The level of plasma Aspergillus IgG LFA in the IA group was significantly higher than that in the control group (190.5 AU/mL vs 50.3 AU/mL, P < 0.001)”

1. Page 06, section 3 Results, sub-section 3.3, paragraph 2

The mistake was the non-uniform writing of “vs.”.

“Compared to the Aspergillus IgG ELISA with a cut-off value of 80 AU/mL, the Aspergillus IgG LFA had equivalent sensitivity (65.1% vs. 69.8% for sensitivity, P = 0.549), but significantly higher specificity (97.5% vs. 87.5% for specificity, P = 0.021)(Table 5).”

The correct statement is “vs”.

“Compared to the Aspergillus IgG ELISA with a cut-off value of 80 AU/mL, the Aspergillus IgG LFA had equivalent sensitivity (65.1% vs 69.8% for sensitivity, P = 0.549), but significantly higher specificity (97.5% vs 87.5% for specificity, P = 0.021)(Table 5).”

2. Page 06, section 3 Results, sub-section 3.4

The mistakes were the non-uniform writings of “vs.” and “to”.

“The ROC curves of Aspergillus IgG LFA had no significant differences between patients with acute and subacute IA (AUC0.812[95% CI: 0.705, 0.919] vs 0.874 [95% CI: 0.780 to 0.967], P =0.401)(Figure 3D). The sensitivities, PPVs and NPVs of the Aspergillus IgG LFA were equivalent between patients with acute and subacute IA (57.6% vs. 73.3% for sensitivity, P = 0.190; 90.5% vs. 91.7% for PPV, P = 1.000; 84.8% vs. 90.7% for NPV, P =0.231)(Table 5).”

The correct statements are “vs” and “,”.

“The ROC curves of Aspergillus IgG LFA had no significant differences between patients with acute and subacute IA (AUC0.812[95% CI: 0.705, 0.919] vs 0.874 [95% CI: 0.780, 0.967], P =0.401)(Figure 3D). The sensitivities, PPVs and NPVs of the Aspergillus IgG LFA were equivalent between patients with acute and subacute IA (57.6% vs 73.3% for sensitivity, P = 0.190; 90.5% vs 91.7% for PPV, P = 1.000; 84.8% vs 90.7% for NPV, P =0.231)(Table 5).”

3. Page 09, section 4 Discussion, paragraph 2

The mistake was the wrong writing of “65.1%”.

“In this study, the sensitivity and specificity of the BALF GM were 65.1% and 90.0%, respectively (Table 6).”

The correct statement is “65.0%”.

“In this study, the sensitivity and specificity of the BALF GM were 65.0% and 90.0%, respectively (Table 6).”

4. Page 09, section 4 Discussion, paragraph 2

The mistakes were the non-uniform writings of “vs.” and “P”.

“A meta-analysis showed that PCR had higher sensitivity for the diagnosis of IA in non-neutropenic patients such as COPD, solid tumors and autoimmune diseases with prolonged corticosteroid therapy, compared to those with HM and/or HSCT/SOT (88% vs. 68%, P < 0.001) (Han et al., 2023).”

The correct statements are “vs” and “P”.

“A meta-analysis showed that PCR had higher sensitivity for the diagnosis of IA in non-neutropenic patients such as COPD, solid tumors and autoimmune diseases with prolonged corticosteroid therapy, compared to those with HM and/or HSCT/SOT (88% vs 68%, P < 0.001) (Han et al., 2023).”

Statements

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

acute invasive aspergillosis, subacute invasive aspergillosis, non-neutropenic patients, Aspergillus IgG lateral flow assay, diagnosis

Citation

Lu Y, Zhong H, Wang Y, Sun C, Li Y, Cai Y, Cai X, Wang J, Zhong J and Su X (2025) Correction: Evaluation of a novel Aspergillus IgG lateral flow assay for the diagnosis of non-neutropenic patients with acute and subacute invasive aspergillosis. Front. Cell. Infect. Microbiol. 15:1659574. doi: 10.3389/fcimb.2025.1659574

Received

04 July 2025

Accepted

07 July 2025

Published

25 July 2025

Approved by

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Volume

15 - 2025

Updates

Copyright

*Correspondence: Xin Su,

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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