Frontiers in Endocrinology

Original Research

Published on 19 Jan 2026

Impact of endometriotic cystectomy on ovarian reserve function and ovulation induction outcomes in women with endometriosis undergoing assisted reproductive technology

in Reproduction

Yutao Li
Yu Gong
Haiyan Jiang
Meng Ji

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1687765

624 views

Original Research

Published on 16 Jan 2026

Pro-inflammatory cytokines disrupt in vitro preantral follicle development by targeting granulosa and theca cell functions

in Reproduction

Aya Shirafuji
Makoto Orisaka
Natsumi Shimizu-Mizuno
Miki Uesaka
Yuko Fujita
Katsutoshi Mizuno
Masayuki Fujita
Yumiko Miyazaki
Toshimichi Onuma
Hideaki Tsuyoshi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1667019

1,066 views

Original Research

Accepted on 14 Jan 2026

Ovarian Rev-erbα: A Central Regulator of Fertility Following Chrono-disruption

in Reproduction

Shalini Gupta
Saumyata Kumawat
Vipashu Kaushal
Rashmi Arora
Sumit Kumar
Rahul Sharma
Anshu Bhardwaj
NEERAJ KHATRI
Pawan Gupta

Frontiers in Endocrinology

160 views

Original Research

Published on 13 Jan 2026

Neutrophil-to-lymphocyte ratio in females as a predictor of embryo acquisition outcomes after IVF/ICSI treatment: a retrospective study

in Reproduction

Liwen Shen
Li Chen
Lifen Chen
Huiping Jiang
Huifeng Gu
Liqun Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705636

634 views

Original Research

Published on 13 Jan 2026

Effects of combined oral contraceptives and metformin on paraoxonase 1 lactonase activity and status in patients with polycystic ovary syndrome and insulin resistance

in Reproduction

Jiagui Liang
Qiuyi Wang
Dong Liu
Lukanxuan Wu
Xinyu Qiao
Ruiying Wang
Yuchan Zhong
Wenjie Bo
Huiqiao Lai
Ping Fan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1725822

900 views

Original Research

Published on 13 Jan 2026

The impact of age on clinical features and fertility outcomes in patients with polycystic ovary syndrome: a secondary analysis based on the PCOSAct trial

in Reproduction

Fengjuan Lu
Hong Yu
Jiaxing Feng
Yang Liu
Hang Ge
Baichao Shi
Muxin Guan
Hongli Ma
Yu Wang
Jing Cong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1697014

936 views

General Commentary

Published on 12 Jan 2026

Commentary: FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization

in Reproduction

Livio Casarini
Manuela Simoni

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706120

456 views

Original Research

Published on 12 Jan 2026

Nurses’ perspectives on injection devices for controlled ovarian stimulation in in-vitro fertilisation: a cross-sectional survey from the GCC countries

in Reproduction

El Samawal Elhakim
Alaa Fouad
Mansour Alorf
Alyah Al Saadoun
Sajida Detho

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1664160

717 views

Original Research

Published on 09 Jan 2026

Amelioration of polycystic ovarian morphology by Tokishakuyakusan in a PCOS rat model: association with bone morphogenetic protein 4

in Reproduction

Mako Ueda
Satoko Osuka
Atsushi Yabuki
Natsuki Miyake
Naoki Fujitsuka
Miwa Nahata
Yohei Tokita
Jiali Ruan
Bayasula
Takehiko Takeda

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1649124

1,319 views

Original Research

Published on 09 Jan 2026

Is endometrial thickness associated with fertility outcomes in intrauterine insemination? a cohort study

in Reproduction

Tong Du
Wentao Li
Suqun Zhang
Qifeng Lyu
Yanping Kuang
Ben W. Mol
Yun Wang
Xiaoyan Mao
Dong Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705695

1,004 views

Original Research

Published on 09 Jan 2026

Predictors of miscarriage in polycystic ovary syndrome patients with threatened abortion: development and validation of a nomogram model

in Reproduction

Luhang Ma
Qingdiao Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689878

867 views

Original Research

Published on 07 Jan 2026

Metabolomic profiling of varicocele-induced male infertility: insights from spermatic vein blood analysis

in Reproduction

Xiyi Wei
Zijie Yu
Shuai Wang
Da Zhong
Yichun Wang
Xi Zhang
Wenchuan Shao
Xinghan Yan
Chao Qin
Ninghong Song

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682362

937 views

Original Research

Published on 07 Jan 2026

Cangfu Daotan decoction treats PCOS-IR through the IL6/JAK2/STAT3/FOXO4 signaling pathway

in Reproduction

Wenhan Ju
Qianwen Zhang
Yue Wang
Keying Pan
Yuan Li
Shuai Zhao
Fang Lian

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1661000

1,017 views

Systematic Review

Published on 05 Jan 2026

Bariatric surgery as a treatment of polycystic ovary syndrome: a systematic review and meta-analysis

in Reproduction

Hyder Mirghani
Amani Shaman

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682379

1,341 views

Mini Review

Published on 05 Jan 2026

Fertility in early breast cancer patients: integrating reproductive planning into oncology care

in Reproduction

Antonella Turla
Anna Bellicini
Daniele Spada
Marcella Mandruzzato

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1695667

942 views

Original Research

Published on 05 Jan 2026

Morinda officinalis oligosaccharides improves sperm motility via the gut microbiota and the IGF-1/PI3K/mTOR signaling pathway

in Reproduction

Jiajia Hu
Guoxuan Li
Bingxue Ouyang
Anguo Wang
Yejuan Li
Hui Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1711475

747 views

Original Research

Published on 05 Jan 2026

Effect of type 2 diabetes mellitus on sperm quality and outcomes of assisted reproductive techniques in infertile male patients

in Reproduction

Rui Wang
Yajuan Zhang
Hui Li
Wanpeng Liu
Lin Xu
Meisong Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1692746

1,063 views

Review

Accepted on 31 Dec 2025

Female reproductive capacity preservation: Antioxidant Strategies in Combating Ovarian Aging and Cryopreservation Challenges

in Reproduction

Bing Xie
Kailing Zhang
Jiao Lin
Cheng Haiying
Xianghong Huang

Frontiers in Endocrinology

316 views

Original Research

Accepted on 30 Dec 2025

Comparing pregnancy outcomes in a population with natural versus surgical reduction of twin pregnancies: a retrospective cohort study

in Reproduction

Yuanxue Jing
Jiawei Gao
Xuzhao Gu
Yi Wan
Xiaoxia He
Xiaoling Ma
Haofei Shen

Frontiers in Endocrinology

221 views

Original Research

Published on 19 Dec 2025

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment

in Reproduction

Arturo A. Canul-Euan
Arturo Flores-Pliego
Juan M. Solis-Paredes
Aurora Espejel-Nuñez
Sandra B. Parra-Hernández
Tahiri Mendoza-Hernández
María del Carmen Hernandez-Chavez
Gabriela Gil-Martínez
Carmen J. Zamora-Sánchez
Otilia Perichart-Perera

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1694018

1,598 views

Review

Published on 19 Dec 2025

Sertoli cells-only syndrome: current clinical approaches and ongoing research trends

in Reproduction

Elena Eugeni
Iva Arato
Francesca Mancuso
Stefano Brancorsini
Giovanni Luca
Sieglinde Kofler

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1715642

1,942 views

Original Research

Published on 17 Dec 2025

Effect of progesterone levels on the hCG trigger day and the progesterone-to-basal progesterone ratio on pregnancy outcomes in fresh IVF/ICSI cycles with GnRH antagonist protocol: a retrospective cohort study

in Reproduction

Lu Guan
Haicui Wu
Yuan Li
Qihui Liang
Xina Zhen
Shan Xiang
Fang Lian

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1653555

1,351 views

Original Research

Published on 17 Dec 2025

Elevated serum chromogranin A levels are independently associated with metabolic and inflammatory disturbances in polycystic ovary syndrome

in Reproduction

Pınar Alarslan
Mehmet Doruk

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682910

1,030 views

Original Research

Published on 17 Dec 2025

Development and validation of an explainable machine learning and nomogram model for early detection and risk stratification of polycystic ovary syndrome: a multicenter study

in Reproduction

Bihua Yao
Xingyu Yu
Yunyan Zhang
Jiayan Chen
Xiaotong Zhu
Cheng Zhang
Tong Jijun

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1719631

1,274 views

2,163 articles

articles

Impact of endometriotic cystectomy on ovarian reserve function and ovulation induction outcomes in women with endometriosis undergoing assisted reproductive technology

Pro-inflammatory cytokines disrupt in vitro preantral follicle development by targeting granulosa and theca cell functions

Ovarian Rev-erbα: A Central Regulator of Fertility Following Chrono-disruption

Neutrophil-to-lymphocyte ratio in females as a predictor of embryo acquisition outcomes after IVF/ICSI treatment: a retrospective study

Effects of combined oral contraceptives and metformin on paraoxonase 1 lactonase activity and status in patients with polycystic ovary syndrome and insulin resistance

The impact of age on clinical features and fertility outcomes in patients with polycystic ovary syndrome: a secondary analysis based on the PCOSAct trial

Commentary: FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization

Nurses’ perspectives on injection devices for controlled ovarian stimulation in in-vitro fertilisation: a cross-sectional survey from the GCC countries

Amelioration of polycystic ovarian morphology by Tokishakuyakusan in a PCOS rat model: association with bone morphogenetic protein 4

Is endometrial thickness associated with fertility outcomes in intrauterine insemination? a cohort study

Predictors of miscarriage in polycystic ovary syndrome patients with threatened abortion: development and validation of a nomogram model

Metabolomic profiling of varicocele-induced male infertility: insights from spermatic vein blood analysis

Cangfu Daotan decoction treats PCOS-IR through the IL6/JAK2/STAT3/FOXO4 signaling pathway

Bariatric surgery as a treatment of polycystic ovary syndrome: a systematic review and meta-analysis

Fertility in early breast cancer patients: integrating reproductive planning into oncology care

Morinda officinalis oligosaccharides improves sperm motility via the gut microbiota and the IGF-1/PI3K/mTOR signaling pathway

Effect of type 2 diabetes mellitus on sperm quality and outcomes of assisted reproductive techniques in infertile male patients

Female reproductive capacity preservation: Antioxidant Strategies in Combating Ovarian Aging and Cryopreservation Challenges

Comparing pregnancy outcomes in a population with natural versus surgical reduction of twin pregnancies: a retrospective cohort study

Placental serotonergic system dysregulation is associated with early impairments in infant neurodevelopment

Sertoli cells-only syndrome: current clinical approaches and ongoing research trends

Effect of progesterone levels on the hCG trigger day and the progesterone-to-basal progesterone ratio on pregnancy outcomes in fresh IVF/ICSI cycles with GnRH antagonist protocol: a retrospective cohort study

Elevated serum chromogranin A levels are independently associated with metabolic and inflammatory disturbances in polycystic ovary syndrome

Development and validation of an explainable machine learning and nomogram model for early detection and risk stratification of polycystic ovary syndrome: a multicenter study