Frontiers in Endocrinology | Systems Endocrinology

Original Research

Published on 14 Aug 2024

Dissecting the mediating role of inflammatory factors in the interaction between metabolites and sepsis: insights from bidirectional Mendelian randomization

in Systems Endocrinology

Fangchen Gong
Wenbin Liu
Lei Pei
Xiaofeng Wang
Xiangtao Zheng
Song Yang
Shanzhi Zhao
Dan Xu
Ranran Li
Zhitao Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1377755

3,707 views

Original Research

Published on 08 Aug 2024

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

in Systems Endocrinology

Fan Li
Zhaodi Wang
Tongyu Tang
Qi Zhao
Zhi Wang
Xiaoping Han
Zifeng Xu
Yu Chang
Hongyan Li
Sileng Hu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1375896

4,595 views
2 citations

Original Research

Published on 30 Jul 2024

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

in Systems Endocrinology

Shuaiwei Song
Xintian Cai
Junli Hu
Qing Zhu
Di Shen
Huimin Ma
Yingying Zhang
Rui Ma
Pan Zhou
Wenbo Yang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1424207

4,264 views
35 citations

Original Research

Published on 08 Jul 2024

The predictive role of the platelet-to-lymphocyte ratio for the risk of non-alcoholic fatty liver disease and cirrhosis: a nationwide cross-sectional study

in Systems Endocrinology

Cheng Yan
Weichang Zhang
Yangyan Xiao
Yuxin Sun
Xinke Peng
Wenwu Cai

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1376894

4,552 views
13 citations

Original Research

Published on 04 Jul 2024

Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a mendelian randomization study

in Systems Endocrinology

Yan Zhong
ChengAn Yang
BingHua Zhang
YingWen Chen
WenJun Cai
GuoChen Wang
ChangWei Zhao
WenHai Zhao

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1378645

5,915 views
7 citations

Mini Review

Published on 04 Jul 2024

Unveiling the role of ferroptosis in the progression from NAFLD to NASH: recent advances in mechanistic understanding

in Systems Endocrinology

Qian Yu
Lixing Song

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1431652

7,215 views
16 citations

Original Research

Published on 28 Jun 2024

Decoding connections in the European population: serum uric acid, sex hormone-binding globulin, total testosterone, estradiol, and female infertility – advanced bidirectional and mediative Mendelian randomization

in Systems Endocrinology

Zilong Tan
Jianwu Shen
Yuxiao Huang
Junru Li
Mengdi Ding
Aochuan Sun
Jing Hong
Yan Yang
Sheng He
Xueying Zhu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1398600

3,936 views
6 citations

Original Research

Published on 26 Jun 2024

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

in Systems Endocrinology

Zhiwen Cao
Yuxiao Zhao
Ruixin Liu
Xialin Yan
Jiqiu Wang
Na Chen

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1414908

3,347 views
1 citation

Original Research

Published on 26 Jun 2024

Associations of oxidative balance score with hyperuricemia and gout among American adults: a population-based study

in Systems Endocrinology

Kai Wang
Jinyi Wu
Minggang Deng
Jiaqi Nie
Fengxi Tao
Qingwen Li
Xin Luo
Fang Xia

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1354704

4,063 views
7 citations

Original Research

Published on 26 Jun 2024

The circadian syndrome is a better predictor for psoriasis than the metabolic syndrome via an explainable machine learning method — the NHANES survey during 2005–2006 and 2009–2014

in Systems Endocrinology

Yunfan Gu
Xinglan Ye
Wenting Zhao
Shiwei He
Weiming Zhang
Xianyu Zeng

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1379130

11,243 views
8 citations

Original Research

Published on 21 Jun 2024

Pro-inflammatory diets promote the formation of hyperuricemia

in Systems Endocrinology

Xin Liu
Ting-Yu Chen
Teng-Yu Gao
Ke-Qin Shi
Fu-Qiang Yin
Yun-Xiang Yu
Chao Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1398917

5,607 views
8 citations

Original Research

Published on 20 Jun 2024

Association between oxidative balance score and serum uric acid and hyperuricemia: a population-based study from the NHANES (2011–2018)

in Systems Endocrinology

Yuhao Yang
Zengxiang Wu
Zhenmei An
Shuangqing Li

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1414075

6,072 views
18 citations

Review

Published on 17 Jun 2024

Insulin resistance in the retina: possible implications for certain ocular diseases

in Systems Endocrinology

Zhaoxia Zheng
Xiaobing Yu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1415521

8,923 views
14 citations

Original Research

Published on 14 Jun 2024

Changes in the serum metabolomics of polycystic ovary syndrome before and after compound oral contraceptive treatment

in Systems Endocrinology

Ting Zhao
Xiao Xiao
Lingchuan Li
Jing Zhu
Wenli He
Qiong Zhang
Jiaqi Wu
Xiaomei Wu
Tao Yuan

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1354214

4,313 views
3 citations

Original Research

Published on 14 Jun 2024

Exploring the relationship between life course adiposity and sepsis: insights from a two-sample Mendelian randomization analysis

in Systems Endocrinology

Zimei Cheng
Jingjing Li
Wenjia Tong
Tingyan Liu
Caiyan Zhang
Jian Ma
Guoping Lu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1413690

3,745 views

Original Research

Published on 13 Jun 2024

Association between systemic immunity-inflammation index and sex hormones in children and adolescents aged 6–19

in Systems Endocrinology

Zijun Gao
Ke Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1355738

3,796 views
4 citations

Original Research

Published on 12 Jun 2024

Eight-day fasting modulates serum kynurenines in healthy men at rest and after exercise

in Systems Endocrinology

Ulana Juhas
Joanna Reczkowicz
Jakub Antoni Kortas
Małgorzata Żychowska
Karol Pilis
Ewa Ziemann
Inga Cytrych
Jędrzej Antosiewicz
Andżelika Borkowska

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1403491

2,715 views
2 citations

Editorial

Published on 11 Jun 2024

Editorial: Omics approaches to delineate the role of gut microbiota-derived metabolites in obesity and metabolic disorders

in Systems Endocrinology

Charalambos Fotakis
Maria Gazouli
Silvia Turroni

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1436678

2,078 views

Opinion

Published on 10 Jun 2024

The proliferation of derivative and redundant studies in endocrinology due to the application of Mendelian Randomisation and other methods to open databases

in Systems Endocrinology

Jonathan H. Tobias
Katherine Samaras
Richard Ivell
Terry F. Davies
Åke Sjöholm
Iwan Day-Haynes
Jeff M.P. Holly

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1400583

2,770 views
1 citation

Editorial

Published on 20 May 2024

Editorial: The RNA revolution and cancer

in Systems Endocrinology

Zodwa Dlamini
Michael R. Ladomery
Abdullah Kahraman

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1422599

4,346 views
5 citations

Original Research

Published on 17 May 2024

Relationship of postprandial fibroblast growth factor 21 with lipids, inflammation and metabolic dysfunction-associated fatty liver disease during oral fat tolerance test

in Systems Endocrinology

Xiaolong Li
Kunjie Zheng
Lifang Liu
Tingxue Zhang
Wei Gu
Xiaoyu Hou
Jianlin Geng
Guangyao Song

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1343853

3,400 views
6 citations

Systematic Review

Published on 30 Apr 2024

The effect of single nucleotide polymorphisms on depression in combination with coronary diseases: a systematic review and meta-analysis

in Systems Endocrinology

Jing Zhang
Lu Gao
Guan Lin Yang
De Zhao Kong

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1369676

5,240 views
7 citations

Original Research

Published on 26 Apr 2024

The association between circadian syndrome and chronic kidney disease in an aging population: a 4-year follow-up study

in Systems Endocrinology

Yang Xiong
Qian Zhong
Yangchang Zhang
Zhihong Liu
Xianding Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1338110

14,282 views
16 citations

Original Research

Published on 04 Apr 2024

Prediction of glycosylated hemoglobin level in patients with cardiovascular diseases and type 2 diabetes mellitus with respect to anti-diabetic medication

in Systems Endocrinology

Alisher Ikramov
Shakhnoza Mukhtarova
Raisa Trigulova
Dilnoza Alimova
Saodat Abdullaeva

Frontiers in Endocrinology

doi 10.3389/fendo.2024.1305640

3,579 views
2 citations

444 articles

articles

Dissecting the mediating role of inflammatory factors in the interaction between metabolites and sepsis: insights from bidirectional Mendelian randomization

From serum metabolites to the gut: revealing metabolic clues to susceptibility to subtypes of Crohn’s disease and ulcerative colitis

Plasma aldosterone concentrations elevation in hypertensive patients: the dual impact on hyperuricemia and gout

The predictive role of the platelet-to-lymphocyte ratio for the risk of non-alcoholic fatty liver disease and cirrhosis: a nationwide cross-sectional study

Causal impact of human blood metabolites and metabolic pathways on serum uric acid and gout: a mendelian randomization study

Unveiling the role of ferroptosis in the progression from NAFLD to NASH: recent advances in mechanistic understanding

Decoding connections in the European population: serum uric acid, sex hormone-binding globulin, total testosterone, estradiol, and female infertility – advanced bidirectional and mediative Mendelian randomization

Identification of ibuprofen targeting CXCR family members to alleviate metabolic disturbance in lipodystrophy based on bioinformatics and in vivo experimental verification

Associations of oxidative balance score with hyperuricemia and gout among American adults: a population-based study

The circadian syndrome is a better predictor for psoriasis than the metabolic syndrome via an explainable machine learning method — the NHANES survey during 2005–2006 and 2009–2014

Pro-inflammatory diets promote the formation of hyperuricemia

Association between oxidative balance score and serum uric acid and hyperuricemia: a population-based study from the NHANES (2011–2018)

Insulin resistance in the retina: possible implications for certain ocular diseases

Changes in the serum metabolomics of polycystic ovary syndrome before and after compound oral contraceptive treatment

Exploring the relationship between life course adiposity and sepsis: insights from a two-sample Mendelian randomization analysis

Association between systemic immunity-inflammation index and sex hormones in children and adolescents aged 6–19

Eight-day fasting modulates serum kynurenines in healthy men at rest and after exercise

Editorial: Omics approaches to delineate the role of gut microbiota-derived metabolites in obesity and metabolic disorders

The proliferation of derivative and redundant studies in endocrinology due to the application of Mendelian Randomisation and other methods to open databases

Editorial: The RNA revolution and cancer

Relationship of postprandial fibroblast growth factor 21 with lipids, inflammation and metabolic dysfunction-associated fatty liver disease during oral fat tolerance test

The effect of single nucleotide polymorphisms on depression in combination with coronary diseases: a systematic review and meta-analysis

The association between circadian syndrome and chronic kidney disease in an aging population: a 4-year follow-up study

Prediction of glycosylated hemoglobin level in patients with cardiovascular diseases and type 2 diabetes mellitus with respect to anti-diabetic medication