Frontiers in Genetics

Original Research

Published on 02 Jul 2025

Prognostic and tumor microenvironmental features of gastric cancer revealed by macrophage polarization and protein lactylation-related genes

in Cancer Genetics and Oncogenomics

Zifan Xu
Zi Lei
Shilan Peng
Sha Li
Dehui Kong
Hongqiong Duan
Man Zhang
Guomiao Su
Guoqing Pan

Frontiers in Genetics

doi 10.3389/fgene.2025.1541489

3,853 views
1 citation

Original Research

Published on 01 Jul 2025

Genome-wide identification of LHT gene family in Lonicera macranthoides Hand.-Mazz and their responses to abiotic stresses

in Evolutionary and Population Genetics

Zhaowu Li
Yue Hu
Chunzhi Liang
Lu Chen
Yao Hu
Xiaoqiu Wu
Xia Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1614541

2,877 views

Mini Review

Published on 01 Jul 2025

Topologically associating domains of chromatin on single-cell Hi-C data: a survey of bioinformatic tools and applications in the light of artificial intelligence

in Statistical Genetics and Methodology

Hongqiang Lyu
Yao Li
Xinran Chen
Yuan Liu
Erhu Liu
Xiaoliang Cheng

Frontiers in Genetics

doi 10.3389/fgene.2025.1602234

2,854 views
1 citation

Original Research

Published on 01 Jul 2025

Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer

in Cancer Genetics and Oncogenomics

Xi Zhang
Long Yu
Cuizhi Geng

Frontiers in Genetics

doi 10.3389/fgene.2025.1586287

2,413 views

Original Research

Published on 27 Jun 2025

Inbreeding patterns and genetic diversity under selection in Teha sheep

in Livestock Genomics

Shunzhe Wang
Long Liang
Dilinigeer Ziyayiding
Wenjing Jiao
Hailati Kasimu
Sangang He
Mingjun Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1576125

2,796 views

Editorial

Published on 27 Jun 2025

Editorial: Screening and discovering novel biological biomarkers by omic-data to revolutionize tumor management

in Cancer Genetics and Oncogenomics

Binglin Wang
Yinan Jiang
Peijie Wu
Enrique Medina-Acosta
Zhongyi Yan

Frontiers in Genetics

doi 10.3389/fgene.2025.1611885

1,724 views

Original Research

Published on 27 Jun 2025

Putative epigenetic regulation mechanisms related to production, carcass and beef quality traits in Nelore cattle

in Epigenomics and Epigenetics

Juliana Afonso
Woo Jun Shim
Tainã Figueiredo Cardoso
Jennifer Jéssica Bruscadin
Andressa Oliveira de Lima
Wellison Jarles da Silva Diniz
Bárbara Silva-Vignato
Ingrid Soares Garcia
Wei Liang Andre Tan
Priscila Silva Neubern de Oliveira

Frontiers in Genetics

doi 10.3389/fgene.2025.1593444

3,061 views
1 citation

Original Research

Published on 26 Jun 2025

Why too much biomedical research is often undeserving of the public’s trust

in ELSI in Science and Genetics

Mark Yarborough

Frontiers in Genetics

doi 10.3389/fgene.2025.1587616

5,721 views

Original Research

Published on 26 Jun 2025

HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction

in Computational Genomics

Fuyu Li
Wenxiang Lu
Yunfei Bai

Frontiers in Genetics

doi 10.3389/fgene.2025.1641162

2,791 views
2 citations

Methods

Published on 25 Jun 2025

Analysis of follow-up data in large biobank cohorts: a review of methodology

in Statistical Genetics and Methodology

Anastassia Kolde
Merli Koitmäe
Meelis Käärik
Märt Möls
Krista Fischer

Frontiers in Genetics

doi 10.3389/fgene.2025.1534726

1,843 views
1 citation

Original Research

Published on 25 Jun 2025

A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data

in Computational Genomics

Fengchun Ren
Xiao Zhao
Qin Yang
Huaqiang Liao
Yudong Zhang
Xuemei Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1631228

2,317 views

Original Research

Published on 25 Jun 2025

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities

in Cytogenomics

Yun Guo
Xiaoqin Xin
Linju Zhou
Jungao Huang

Frontiers in Genetics

doi 10.3389/fgene.2025.1611388

3,467 views

Original Research

Published on 25 Jun 2025

Association of the interaction between occupational hazard factors and IL-1β gene polymorphism with cognitive function in electrolytic aluminum workers

in Applied Genetic Epidemiology

Youxing Li
Yaqin Pang
Dongshun Chen
Feiyu Lu
Hongyan Tian
Fengni Qin
Kuntao Wei
Ahmad Razali Bin Ishak
Mohd Shukri Bin Mohd Aris
Guangzi Qi

Frontiers in Genetics

doi 10.3389/fgene.2025.1591908

1,881 views

Correction

Published on 25 Jun 2025

Correction: Genetic landscape of hypertrophic cardiomyopathy in Hong Kong Chinese population

in Evolutionary and Population Genetics

Derek P. H. Lee
Ye Cao
Lilei Zhang

Frontiers in Genetics

doi 10.3389/fgene.2025.1641043

1,418 views

Original Research

Published on 24 Jun 2025

Association of the MUC5B promoter polymorphism with idiopathic pulmonary fibrosis in a lebanese cohort

in Genetics of Common and Rare Diseases

Antoine Mouawad
Eliane Chouery
Alain Chebly
Nabiha Salem
Sandra Corbani
Maissa Safieddine
Georges Dabar

Frontiers in Genetics

doi 10.3389/fgene.2025.1544864

2,441 views

Original Research

Published on 24 Jun 2025

Shared genetic loci connect cardiovascular disease with blood pressure and lipid traits in East Asian populations

in Applied Genetic Epidemiology

Peng Zhong
Chumeng Zhang
Qinfeng Wu
Xiao Chang

Frontiers in Genetics

doi 10.3389/fgene.2025.1635378

3,031 views
1 citation

Original Research

Published on 24 Jun 2025

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

in Computational Genomics

Yingnan Li
Ning Xiao
Zhuoqun Wang
Wenhai Wang
Fengjiao Li
Jiren Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1620749

3,006 views

Case Report

Published on 24 Jun 2025

Case Report: Novel truncating PPM1D variant in a dichorionic diamniotic (DCDA) twin with Jansen-de Vries syndrome. an updated perspective

in Genetics of Common and Rare Diseases

Francisco Javier Merida De la Torre
Javier Porta Pelayo
Inmaculada Ortiz-Martín

Frontiers in Genetics

doi 10.3389/fgene.2025.1601752

2,048 views

Review

Published on 24 Jun 2025

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

in Pharmacogenetics and Pharmacogenomics

Siva Hamdani
Laniyati Hamijoyo
Riezki Amalia
Melisa I. Barliana

Frontiers in Genetics

doi 10.3389/fgene.2025.1594648

4,706 views
2 citations

Review

Published on 24 Jun 2025

Key genes of vitamin D metabolism and their roles in the risk and prognosis of cancer

in Nutritional Genomics

Sijie Zheng
Lizhu Zhu
Yufei Wang
Yixin Hua
Jie Ying
Jianxiang Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1598525

5,575 views
2 citations

Original Research

Published on 23 Jun 2025

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

in Computational Genomics

Jingya Xu
Zhonghua Dong
Zhaodong Li
Xuan Wang

Frontiers in Genetics

doi 10.3389/fgene.2025.1592985

3,044 views

Original Research

Published on 23 Jun 2025

Shared pathogenesis in polycystic ovaries and rheumatoid arthritis: an analysis of key genes and pathways

in Genetics of Common and Rare Diseases

Yingying Ji
Pengcheng Xia
Yan Wang
Yang Liu
Feng Wang
Fenggang Sun
Qiang Feng
Qingbin Ni
Yi Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1554139

3,161 views

Case Report

Published on 23 Jun 2025

Case Report: Incidental late-onset Pompe disease diagnosis in a man with no clinical and instrumental evidence of neuromuscular dysfunction

in Genetics of Common and Rare Diseases

Monica Sciacco
Sabrina Lucchiari
Letizia Bertolasi
Giacomo Pietro Comi
Stefania Corti
Dario Ronchi

Frontiers in Genetics

doi 10.3389/fgene.2025.1574381

3,287 views

Original Research

Published on 23 Jun 2025

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains

in Computational Genomics

Xudong Wu
Tingting Liu

Frontiers in Genetics

doi 10.3389/fgene.2025.1544802

1,676 views

16,562 articles

articles

Prognostic and tumor microenvironmental features of gastric cancer revealed by macrophage polarization and protein lactylation-related genes

Genome-wide identification of LHT gene family in Lonicera macranthoides Hand.-Mazz and their responses to abiotic stresses

Topologically associating domains of chromatin on single-cell Hi-C data: a survey of bioinformatic tools and applications in the light of artificial intelligence

Expression characteristics, molecular mechanisms, and clinical significance of DICER1 in breast cancer

Inbreeding patterns and genetic diversity under selection in Teha sheep

Editorial: Screening and discovering novel biological biomarkers by omic-data to revolutionize tumor management

Putative epigenetic regulation mechanisms related to production, carcass and beef quality traits in Nelore cattle

Why too much biomedical research is often undeserving of the public’s trust

HyenaCircle: a HyenaDNA-based pretrained large language model for long eccDNA prediction

Analysis of follow-up data in large biobank cohorts: a review of methodology

A machine learning framework for predicting cognitive impairment in aging populations using urinary metal and demographic data

Application of chromosome microarray analysis and karyotyping in fetal cardiac abnormalities

Association of the interaction between occupational hazard factors and IL-1β gene polymorphism with cognitive function in electrolytic aluminum workers

Correction: Genetic landscape of hypertrophic cardiomyopathy in Hong Kong Chinese population

Association of the MUC5B promoter polymorphism with idiopathic pulmonary fibrosis in a lebanese cohort

Shared genetic loci connect cardiovascular disease with blood pressure and lipid traits in East Asian populations

An analysis of gene expression profiles through machine learning uncovers the new diagnostic signature for diabetic foot ulcers

Case Report: Novel truncating PPM1D variant in a dichorionic diamniotic (DCDA) twin with Jansen-de Vries syndrome. an updated perspective

Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

Key genes of vitamin D metabolism and their roles in the risk and prognosis of cancer

CYLD as a key regulator of myocardial infarction-to-heart failure transition revealed by multi-omics integration

Shared pathogenesis in polycystic ovaries and rheumatoid arthritis: an analysis of key genes and pathways

Case Report: Incidental late-onset Pompe disease diagnosis in a man with no clinical and instrumental evidence of neuromuscular dysfunction

Insights into the evolution and regulation of miRNAs from the view of their DNA replication temporal domains