Frontiers in Genetics | Applied Genetic Epidemiology

Original Research

Published on 22 May 2024

Genetic variants in DBC1, SIRT1, UCP2 and ADRB2 as potential biomarkers for severe obesity and metabolic complications

in Applied Genetic Epidemiology

Ana Carolina Proença da Fonseca
Izadora Sthephanie da Silva Assis
Kaio Cezar Rodrigues Salum
Lohanna Palhinha
Gabriella de Medeiros Abreu
Verônica Marques Zembrzuski
Mario Campos Junior
José Firmino Nogueira-Neto
Amanda Cambraia
Mauro Lucio Ferreira Souza Junior

Frontiers in Genetics

doi 10.3389/fgene.2024.1363417

5,229 views
7 citations

Original Research

Published on 21 May 2024

Exploring the causal relationships between rheumatoid arthritis and oral phenotypes: a genetic correlation and Mendelian randomization study

in Applied Genetic Epidemiology

Jindan Shen
Yimei Lou
Liping Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1383696

3,216 views

Original Research

Published on 17 May 2024

Genetic determinants of serum bilirubin using inferred native American gene variants in Chilean adolescents

in Applied Genetic Epidemiology

José P. Miranda
Ana Pereira
Camila Corvalán
Juan F. Miquel
Gigliola Alberti
Juan C. Gana
José L. Santos

Frontiers in Genetics

doi 10.3389/fgene.2024.1382103

2,901 views
5 citations

Methods

Published on 16 May 2024

Longitudinal method comparison: modeling polygenic risk for post-traumatic stress disorder over time in individuals of African and European ancestry

in Applied Genetic Epidemiology

Kristin Passero
Jennie G. Noll
Shefali Setia Verma
Claire Selin
Molly A. Hall

Frontiers in Genetics

doi 10.3389/fgene.2024.1203577

2,231 views
1 citation

Original Research

Published on 15 May 2024

Genetic association and transferability for urinary albumin-creatinine ratio as a marker of kidney disease in four Sub-Saharan African populations and non-continental individuals of African ancestry

in Applied Genetic Epidemiology

Jean-Tristan Brandenburg
Wenlong Carl Chen
Palwende Romuald Boua
Melanie A. Govender
Godfred Agongo
Lisa K. Micklesfield
Hermann Sorgho
Stephen Tollman
Gershim Asiki
Felistas Mashinya

Frontiers in Genetics

doi 10.3389/fgene.2024.1372042

4,867 views
4 citations

Original Research

Published on 15 May 2024

Genotype-based “virtual” metabolomics in a clinical biobank identifies novel metabolite-disease associations

in Applied Genetic Epidemiology

Minoo Bagheri
Andrei Bombin
Mingjian Shi
Venkatesh L. Murthy
Ravi Shah
Jonathan D. Mosley
Jane F. Ferguson

Frontiers in Genetics

doi 10.3389/fgene.2024.1392622

3,473 views
3 citations

Original Research

Published on 09 May 2024

The impact of serum uric acid on psoriasis: NHANES 2005–2014 and Mendelian randomization

in Applied Genetic Epidemiology

Minghui Hu
Yangyang Wang
Wenwu Xu
Juan Bai
Xingming Tang

Frontiers in Genetics

doi 10.3389/fgene.2024.1334781

5,358 views
5 citations

Original Research

Published on 09 May 2024

Genetic liability to inflammatory bowel disease is causally associated with increased risk of erectile dysfunction: Evidence from a bidirectional Mendelian randomization study

in Applied Genetic Epidemiology

Renbing Pan
Chuanyang Sun
Linhai Zheng
Jingwen Liu
Wei Xu

Frontiers in Genetics

doi 10.3389/fgene.2024.1334972

2,163 views
3 citations

Original Research

Published on 01 May 2024

Association between migraine and venous thromboembolism: a Mendelian randomization and genetic correlation study

in Applied Genetic Epidemiology

Xu-Peng Wu
Peng-Peng Niu
Hong Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1272599

3,919 views
3 citations

Original Research

Published on 25 Apr 2024

Causal associations of cognition, intelligence, education, health and lifestyle factors with cervical spondylosis: a mendelian randomization study

in Applied Genetic Epidemiology

Zhenxiao Ren
Xing Cheng
Jinghui Xu
Tianzuo Niu
Houqing Long

Frontiers in Genetics

doi 10.3389/fgene.2024.1297213

3,826 views
2 citations

Original Research

Published on 19 Apr 2024

Dissecting the shared genetic architecture between Alzheimer’s disease and frailty: a cross-trait meta-analyses of genome-wide association studies

in Applied Genetic Epidemiology

Nitesh Enduru
Brisa S. Fernandes
Zhongming Zhao

Frontiers in Genetics

doi 10.3389/fgene.2024.1376050

5,374 views
6 citations

Original Research

Published on 18 Apr 2024

Circulating VEGF and inflammatory bowel disease: a bidirectional mendelian randomization

in Applied Genetic Epidemiology

Haishan Lin
Bangwei Cao

Frontiers in Genetics

doi 10.3389/fgene.2024.1282471

3,116 views
3 citations

Original Research

Published on 10 Apr 2024

Screening for thalassemia carriers among the Han population of childbearing age in Southwestern of China

in Applied Genetic Epidemiology

Yepei Du
Cong Zhou
Jing Wang
Yanting Yang
Hui Liu

Frontiers in Genetics

doi 10.3389/fgene.2024.1356068

3,803 views
5 citations

Original Research

Published on 28 Mar 2024

Evaluating cardiovascular disease risk stratification using multiple-polygenic risk scores and pooled cohort equations: insights from a 17-year longitudinal Korean cohort study

in Applied Genetic Epidemiology

Yi Seul Park
Hye-Mi Jang
Ji Hye Park
Bong-Jo Kim
Hyun-Young Park
Young Jin Kim

Frontiers in Genetics

doi 10.3389/fgene.2024.1364993

4,265 views
2 citations

Original Research

Published on 27 Mar 2024

Causal association of gastroesophageal reflux disease on irritable bowel syndrome: a two-sample Mendelian randomization study

in Applied Genetic Epidemiology

Huihuan Wu
Jingwei Li
FeiFei Li
Weijian Lun

Frontiers in Genetics

doi 10.3389/fgene.2024.1328327

4,842 views
2 citations

Original Research

Published on 22 Mar 2024

Systemic inflammatory regulators and preeclampsia: a two-sample bidirectional Mendelian randomization study

in Applied Genetic Epidemiology

Chu Li
Yishu Tian
Djouhayna Dougarem
Litao Sun
Zixing Zhong

Frontiers in Genetics

doi 10.3389/fgene.2024.1359579

5,407 views
7 citations

Review

Published on 13 Mar 2024

Association of glutamate receptor gene polymorphisms with attention-deficit hyperactivity disorder susceptibility: a systematic review and meta-analysis

in Applied Genetic Epidemiology

Dehua Zou
Qiaoli Zeng
Pei Liu
Yue Wei
Runmin Guo
Yizhun Zhu
Rong-Rong He

Frontiers in Genetics

doi 10.3389/fgene.2024.1348387

3,935 views
2 citations

Original Research

Published on 07 Mar 2024

Searching for gene-gene interactions through variance quantitative trait loci of 29 continuous Taiwan Biobank phenotypes

in Applied Genetic Epidemiology

Wan-Yu Lin

Frontiers in Genetics

doi 10.3389/fgene.2024.1357238

2,458 views
2 citations

Original Research

Published on 07 Mar 2024

Mendelian randomization study shows no causal relationship between psychiatric disorders and glaucoma in European and East Asian populations

in Applied Genetic Epidemiology

Yan Zhang
Longhui Fu
Fang Feng
Bo Liu
Ying Lei
Qianyan Kang

Frontiers in Genetics

doi 10.3389/fgene.2024.1349860

3,625 views
3 citations

Original Research

Published on 01 Mar 2024

Metabolic syndrome traits exhibit genotype-by-environment interaction in relation to socioeconomic status in the Mexican American family heart study

in Applied Genetic Epidemiology

Vincent P. Diego
Eron G. Manusov
Xi Mao
Marcio Almeida
Juan M. Peralta
Joanne E. Curran
Michael C. Mahaney
Harald Göring
John Blangero
Sarah Williams-Blangero

Frontiers in Genetics

doi 10.3389/fgene.2024.1240462

3,282 views
3 citations

Brief Research Report

Published on 26 Feb 2024

Differentially expressed microRNAs targeting genes in key pathways in keratoconus

in Applied Genetic Epidemiology

Dorota M. Nowak-Malczewska
Joanna Swierkowska
Marzena Gajecka

Frontiers in Genetics

doi 10.3389/fgene.2024.1301676

4,608 views
7 citations

Original Research

Published on 22 Feb 2024

Association of sleep traits with male fertility: a two-sample Mendelian randomization study

in Applied Genetic Epidemiology

Shikuan Lu
Ziyang Ma
Wanzhen Zhou
Hongsen Zeng
Jian Ma
Hang Deng
Peihai Zhang

Frontiers in Genetics

doi 10.3389/fgene.2024.1353438

8,989 views
8 citations

Original Research

Published on 19 Feb 2024

Using genetics to investigate the association between lanosterol and cataract

in Applied Genetic Epidemiology

Munisa Hashimi
Hasnat A. Amin
Loukas Zagkos
Alexander C. Day
Fotios Drenos

Frontiers in Genetics

doi 10.3389/fgene.2024.1231521

5,911 views
5 citations

Original Research

Published on 07 Feb 2024

Leveraging the transcriptome to further our understanding of GWAS findings: eQTLs associated with genes related to LDL and LDL subclasses, in a cohort of African Americans

in Applied Genetic Epidemiology

Malak Abbas
Ana Diallo
Gabriel Goodney
Amadou Gaye

Frontiers in Genetics

doi 10.3389/fgene.2024.1345541

2,835 views
1 citation

451 articles

articles

Genetic variants in DBC1, SIRT1, UCP2 and ADRB2 as potential biomarkers for severe obesity and metabolic complications

Exploring the causal relationships between rheumatoid arthritis and oral phenotypes: a genetic correlation and Mendelian randomization study

Genetic determinants of serum bilirubin using inferred native American gene variants in Chilean adolescents

Longitudinal method comparison: modeling polygenic risk for post-traumatic stress disorder over time in individuals of African and European ancestry

Genetic association and transferability for urinary albumin-creatinine ratio as a marker of kidney disease in four Sub-Saharan African populations and non-continental individuals of African ancestry

Genotype-based “virtual” metabolomics in a clinical biobank identifies novel metabolite-disease associations

The impact of serum uric acid on psoriasis: NHANES 2005–2014 and Mendelian randomization

Genetic liability to inflammatory bowel disease is causally associated with increased risk of erectile dysfunction: Evidence from a bidirectional Mendelian randomization study

Association between migraine and venous thromboembolism: a Mendelian randomization and genetic correlation study

Causal associations of cognition, intelligence, education, health and lifestyle factors with cervical spondylosis: a mendelian randomization study

Dissecting the shared genetic architecture between Alzheimer’s disease and frailty: a cross-trait meta-analyses of genome-wide association studies

Circulating VEGF and inflammatory bowel disease: a bidirectional mendelian randomization

Screening for thalassemia carriers among the Han population of childbearing age in Southwestern of China

Evaluating cardiovascular disease risk stratification using multiple-polygenic risk scores and pooled cohort equations: insights from a 17-year longitudinal Korean cohort study

Causal association of gastroesophageal reflux disease on irritable bowel syndrome: a two-sample Mendelian randomization study

Systemic inflammatory regulators and preeclampsia: a two-sample bidirectional Mendelian randomization study

Association of glutamate receptor gene polymorphisms with attention-deficit hyperactivity disorder susceptibility: a systematic review and meta-analysis

Searching for gene-gene interactions through variance quantitative trait loci of 29 continuous Taiwan Biobank phenotypes

Mendelian randomization study shows no causal relationship between psychiatric disorders and glaucoma in European and East Asian populations

Metabolic syndrome traits exhibit genotype-by-environment interaction in relation to socioeconomic status in the Mexican American family heart study

Differentially expressed microRNAs targeting genes in key pathways in keratoconus

Association of sleep traits with male fertility: a two-sample Mendelian randomization study

Using genetics to investigate the association between lanosterol and cataract

Leveraging the transcriptome to further our understanding of GWAS findings: eQTLs associated with genes related to LDL and LDL subclasses, in a cohort of African Americans