Frontiers in Genetics | Cancer Genetics and Oncogenomics

Original Research

Published on 20 May 2025

IFI35 and IFIT3 are potentially important biomarkers for early diagnosis and treatment of esophageal squamous cell carcinoma: based on WGCNA and machine learning analysis

in Cancer Genetics and Oncogenomics

Hao Wu
Liang Yang
Xiaokun Weng

Frontiers in Genetics

doi 10.3389/fgene.2025.1583202

903 views

Original Research

Published on 20 May 2025

Impact of ITH on PRAD patients and feasibility analysis of the positive correlation gene MYLK2 applied to PRAD treatment

in Cancer Genetics and Oncogenomics

Chuanyu Ma
Guandu Li
Xiaohan Song
Xiaochen Qi
Tao Jiang

Frontiers in Genetics

doi 10.3389/fgene.2025.1589259

950 views

Original Research

Published on 19 May 2025

Analysis of the correlation between RFC4 expression and tumor immune microenvironment and prognosis in patients with cervical cancer

in Cancer Genetics and Oncogenomics

Bifen Huang
Jianqing Zheng
Bizhen Chen
Min Wu
Lihua Xiao

Frontiers in Genetics

doi 10.3389/fgene.2025.1514383

1,088 views

Original Research

Published on 14 May 2025

Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity

in Cancer Genetics and Oncogenomics

Yupeng Xu
Jian Sun
Xin Yan
Zhenliao Mao
Yiming Chen

Frontiers in Genetics

doi 10.3389/fgene.2025.1457204

914 views

Original Research

Published on 09 May 2025

Expression and clinical significance of FANCI gene in pan-cancer: a comprehensive analysis based on multi-omics data

in Cancer Genetics and Oncogenomics

Yunzheng Zhao
Qingyu Li
Jiajun Li
YiFeng Cui
Zhaoyang Lu

Frontiers in Genetics

doi 10.3389/fgene.2025.1542888

1,389 views

Original Research

Published on 02 May 2025

RNA hybrid-capture next-generation sequencing has high sensitivity in identifying known and less characterized oncogenic and likely oncogenic NTRK fusions in a real-world standard-of-care setting

in Cancer Genetics and Oncogenomics

Zachary D. Wallen
Marni Tierno
Erica Schnettler
Alison Roos
Michelle Green
Kobina Amoah
Rebecca A. Previs
Stephanie Hastings
Sarabjot Pabla
Taylor J. Jensen

Frontiers in Genetics

doi 10.3389/fgene.2025.1550706

2,959 views

Review

Published on 01 May 2025

In vitro 3D modeling of colorectal cancer: the pivotal role of the extracellular matrix, stroma and immune modulation

in Cancer Genetics and Oncogenomics

Veroniaina Hanitrarimalala
Zdenka Prgomet
My Hedhammar
Helena Tassidis
Anette Gjörloff Wingren

Frontiers in Genetics

doi 10.3389/fgene.2025.1545017

1,542 views

Original Research

Published on 01 May 2025

Radiomic features and tumor immune microenvironment associated with anaplastic lymphoma kinase-rearranged lung adenocarcinoma and their prognostic value

in Cancer Genetics and Oncogenomics

Ying Han
Wenya Feng
Huaxin Li
Hua Wang
Zhaoxiang Ye

Frontiers in Genetics

doi 10.3389/fgene.2025.1581937

1,113 views

Original Research

Published on 25 Apr 2025

A rare germline mutation reverses the suppressive effect of GPC5 thereby promoting lung adenocarcinoma development and tumorigenesis

in Cancer Genetics and Oncogenomics

Zhifa Zheng
Lina Zhao
Sen Zhao
Zhihong Wu
Nan Wu

Frontiers in Genetics

doi 10.3389/fgene.2025.1582504

979 views

Original Research

Published on 22 Apr 2025

RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Alan Chu
Xiao Liu
Shijia Liu
Mengxi Li
Rui Song
Lanlan Gan
Yongtai Wang
Zongwen Liu
Chen Sun

Frontiers in Genetics

doi 10.3389/fgene.2025.1549371

797 views

Original Research

Published on 15 Apr 2025

The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma

in Cancer Genetics and Oncogenomics

Deyuan Li
Meiliang Liu
Mingshuang Lai
Lijun Wang
Liling Wei
Siqian Wu
Si Liang
Shun Liu
Xiaoyun Zeng

Frontiers in Genetics

doi 10.3389/fgene.2025.1521360

1,192 views

Original Research

Published on 14 Apr 2025

Identification of characteristic genes in cutaneous squamous cell carcinoma based on weighted gene co-expression network analysis

in Cancer Genetics and Oncogenomics

Qipeng Xiao
Pengfei Xu
Wenjun Xu
Qiuhe Song
Yousheng Mao

Frontiers in Genetics

doi 10.3389/fgene.2025.1470584

1,143 views

Original Research

Published on 07 Apr 2025

Immunogenic cell death genes in single-cell and transcriptome analyses perspectives from a prognostic model of cervical cancer

in Cancer Genetics and Oncogenomics

Li Ning
Xiu Li
Yating Xu
Yu Si
Hongting Zhao
Qinling Ren

Frontiers in Genetics

doi 10.3389/fgene.2025.1532523

1,446 views

Original Research

Published on 04 Apr 2025

Biological characteristics and prognosis of acute myeloid leukemia in elderly patients

in Cancer Genetics and Oncogenomics

Zhe Chen
Lina Ding
Jieni Yu
Jing Jin
Zhijian Zhang
Jiaping Fu
Pan Hong
Leihua Fu

Frontiers in Genetics

doi 10.3389/fgene.2025.1524177

886 views

Original Research

Published on 04 Apr 2025

Transcriptomic signature can distinguish chronic neutrophilic leukemia from ambiguous neutrophilic leukemias

in Cancer Genetics and Oncogenomics

Chao Guo
Zhen-Ling Li

Frontiers in Genetics

doi 10.3389/fgene.2025.1556519

947 views

Original Research

Published on 04 Apr 2025

The gene signature linked to lactate metabolism predicts the prognosis and correlates with the immune status of head and neck squamous cell carcinoma

in Cancer Genetics and Oncogenomics

Jian Xiao
Wei Li
Guolin Tan
Ru Gao

Frontiers in Genetics

doi 10.3389/fgene.2025.1540841

1,005 views