Frontiers in Immunology

Review

Accepted on 08 Dec 2025

From Arthritis to Central Sensitization: Targeting the Neuro-Immune Axis via Microglial Modulation in Acupuncture Treatment for Juvenile Idiopathic Arthritis (JIA)-Associated Pain

in Multiple Sclerosis and Neuroimmunology

Hang CHEN
Xu JiXiang
Xia Zhang

Frontiers in Immunology

128 views

Original Research

Accepted on 08 Dec 2025

Outcomes and predictors of relapse and severe pneumonia in Chinese patients with AQP4-IgG-positive neuromyelitis optica spectrum disorder receiving inebilizumab: a prospective cohort study

in Multiple Sclerosis and Neuroimmunology

Wenjuan Huang
Hongmei Tan
Jingzi Zhangbao
Liang Wang
Yuxin Fan
Zhouzhou Wang
Chongbo Zhao
Jiahong Lu
Qiang Dong
LEI ZHOU

Frontiers in Immunology

102 views

Original Research

Accepted on 08 Dec 2025

Integrated Analysis of Single-Cell and Bulk Transcriptomes Reveals the Prognostic Value of Polyamine Metabolism Biomarkers and Immune Microenvironment Features in Gastric Cancer

in Cancer Immunity and Immunotherapy

Kailun Chen
Yuteng Chen
Qinqin Hu
Jie Zheng
Yanan Liu

Frontiers in Immunology

Original Research

Accepted on 08 Dec 2025

Dysregulated Tfh/B cells and their interactions in neuromyelitis optica spectrum disorder

in Multiple Sclerosis and Neuroimmunology

Liang Wang
LEI ZHOU
Zhouzhou Wang
Jingzi Zhangbao
Wenjuan Huang
Hongmei Tan
Yuxin Fan
Chuanzhen Lu
Jian Yu
Min Wang

Frontiers in Immunology

Original Research

Accepted on 08 Dec 2025

MCP-1/CCR2 Axis Regulates M2 Macrophage Polarization and Immunosuppression in Mycobacterium Tuberculosis

in Microbial Immunology

Guizeng Zhao
Can Guo
Xiaoyang Li
Lei Tan
Xueyang Chen
Feng Tian
Lili Zhang
Xia Wang
Junwei Cui

Frontiers in Immunology

180 views

Review

Accepted on 08 Dec 2025

Post-translational modification of NK cell receptors offers clues to antigenic specificity riddle

in Immunological Memory

Maria O. Ustiuzhanina
Elena I Kovalenko
Dmitry M Chudakov

Frontiers in Immunology

145 views

Review

Accepted on 08 Dec 2025

The clinical characteristics, mechanism and management of immune checkpoint inhibitor-related arthritis

in Inflammation

Jian Gao
Jinlin Miao
Ping Zhu
Zhinan Chen

Frontiers in Immunology

Brief Research Report

Accepted on 08 Dec 2025

Ravulizumab in NMOSD with Associated Interstitial Pneumonitis in a 59-Year-Old Female Patient: A Case Report

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Andrea Neundorf
Ralf Dittrich

Frontiers in Immunology

Original Research

Accepted on 08 Dec 2025

Influencing Factor Analysis and Prediction Model Construction of Dupilumab Treatment Adherence: A Prospective Cohort Study in Moderate-to-Severe Atopic Dermatitis

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Pingxiang Ouyang
Siyu Yan
Jinrong Zeng
Lihua Gao
Lina Tan
Jianyun Lu

Frontiers in Immunology

139 views

Review

Accepted on 08 Dec 2025

BUILDING ALLIANCES FOR EARLY DETECTION OF IMMUNODEFICIENCIES: FROM PRIMARY CARE TO HEMATOLOGY

in Primary Immunodeficiencies

Jacques G. Rivière
Marlène Pasquet
Eleonora Gambineri

Frontiers in Immunology

165 views

Original Research

Accepted on 08 Dec 2025

Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF–induced trained immunity

in Immunological Memory

Yuanyuan Liu
Arslan Hamid
Hannah Hardege
Qian Zhang
Helena Körner
Merle Leffers
Noelia Alonso Gonzalez
Gerhard Liebisch
Marcus Hoering
Hannes Findeisen

Frontiers in Immunology

184 views

Original Research

Accepted on 08 Dec 2025

Regnase-1 in cDC1 Controls T Cell Priming and Shapes the Dynamics of Experimental Autoimmune Encephalomyelitis

in Molecular Innate Immunity

Osamu Takeuchi
Xingyu Rong
Hai Wang
Shintaro Muraoka
Takuya Uehata
Masanori Yoshinaga
Tsuneyasu Kaisho

Frontiers in Immunology

206 views

Original Research

Accepted on 08 Dec 2025

Modulation of IRAK4 as a Therapeutic Strategy Against Monosodium Urate-and Xanthine-Induced Inflammation in Macrophages and HepG2 Cells

in Molecular Innate Immunity

Sadiq Umar
Huan T Chang
Mark M Cline
Sriram Ravindran

Frontiers in Immunology

132 views

Original Research

Accepted on 08 Dec 2025

m-EASIX (better than EASIX) predicts severe CAR T-cell toxicities, worse Overall Survival, and discriminates Cytokine Release Syndrome from sepsis

in Cancer Immunity and Immunotherapy

Ana Belen Moreno-Castaño
Sara Fernandez Mendez
Helena Brillembourg
Gontzal Iraola
Helena Ventosa-Capell
Julia Martinez-Sanchez
Blanca De Moner Rafel
Patricia Molina
Alex Ramos
Marta Palomo

Frontiers in Immunology

Review

Accepted on 08 Dec 2025

Recent Advances on Hippo-YAP Pathway in Skin Diseases

in Inflammation

Xuxia Cai
Kexin Chen
Xiahong Li
Kaoyuan Zhang
Jiaxu Gu
Changbing Shen
Bo Yu
Cong Huang

Frontiers in Immunology

Review

Accepted on 08 Dec 2025

GSDME in cardiovascular diseases: research system and contemporary progress

in Inflammation

Zhenzhen Yang
Zilong Luo
Han Zhang
Junjie Zong
Pinyan Huang
Yuqing Niu
Cheng Zhou
Song Wang
Dan Zhang

Frontiers in Immunology

Original Research

Published on 08 Dec 2025

Comprehensive analysis of palmitoylation-related proteins for prognostic risk evaluation and tumor immune microenvironment assessment in glioma

in Cancer Immunity and Immunotherapy

Jihao Xue
Li Lin
Chang Liu
Qijia Yin
Tao Wang
Rui Lai
Ligang Chen
Yiran Yin
Ming Wang
Jie Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599769

634 views

Original Research

Published on 08 Dec 2025

Development and validation of immunotherapy nomogram for predicting the efficacy and prognosis of recurrent and metastatic cervical cancer

in Cancer Immunity and Immunotherapy

Zhongan Liu
Sijia Zhang
Yan Wang
Yan Zong
Tian Zhou
Daying Wu
Ganxin Wang
Lihong He
Kai Huang
Yunqing Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662605

583 views

Mini Review

Published on 08 Dec 2025

Gut microbiota metabolites in the immunoregulation of enteritis: research progress

in Mucosal Immunity

Shaochen Yu
Mengjie Zhang
Ziyue Dou
Beibei Tian
Jian Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1706472

750 views

Original Research

Published on 08 Dec 2025

Immunogenicity risk assessment of peptide-related impurities identified in generic teriparatide products

in Immunological Tolerance and Regulation

Aimee E. Mattei
Brian J. Roberts
Sandra Lelias
Shah Miah
Kristina E. Howard
James L. Weaver
Daniela Verthelyi
Eric S. Pang
Katie Edwards
Anne S. De Groot

Frontiers in Immunology

doi 10.3389/fimmu.2025.1730346

1,407 views

Review

Published on 08 Dec 2025

Significance and challenges of immunopharmacogenomics

in Cancer Immunity and Immunotherapy

Lara Hanci Handzha
Yusuke Nakamura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1711887

490 views

Original Research

Published on 08 Dec 2025

A 20-year real-world study on drug survival and predictive factors for infliximab discontinuation in Behçet’s syndrome

in Autoimmune and Autoinflammatory Disorders: Autoinflammatory Disorders

Rosaria Talarico
Antonello Sulis
Federica Di Cianni
Diana Marinello
Maria Laura Manca
Marta Mosca

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726690

368 views

Original Research

Published on 08 Dec 2025

Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in human and macaque

in Vaccines and Molecular Therapeutics

William D. Tolbert
Paula B. Nhan
Haleigh E. Conley
Xiaoxuan Ge
Monika Chandravanshi
Madeleine Lee
Julianna Veilleux
Marek Korzeniowski
Suneetha Gottumukkala
Margaret E. Ackerman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1726068

524 views

Review

Published on 08 Dec 2025

From immune suppression to immunotherapy sensitization: the dual roles of circRNAs in cancer progression

in Cancer Immunity and Immunotherapy

Quan Dai
Xiaoli Yuan
Hang Dong
Haiyi Xue

Frontiers in Immunology

doi 10.3389/fimmu.2025.1723383

512 views

48,462 articles

articles

From Arthritis to Central Sensitization: Targeting the Neuro-Immune Axis via Microglial Modulation in Acupuncture Treatment for Juvenile Idiopathic Arthritis (JIA)-Associated Pain

Outcomes and predictors of relapse and severe pneumonia in Chinese patients with AQP4-IgG-positive neuromyelitis optica spectrum disorder receiving inebilizumab: a prospective cohort study

Integrated Analysis of Single-Cell and Bulk Transcriptomes Reveals the Prognostic Value of Polyamine Metabolism Biomarkers and Immune Microenvironment Features in Gastric Cancer

Dysregulated Tfh/B cells and their interactions in neuromyelitis optica spectrum disorder

MCP-1/CCR2 Axis Regulates M2 Macrophage Polarization and Immunosuppression in Mycobacterium Tuberculosis

Post-translational modification of NK cell receptors offers clues to antigenic specificity riddle

The clinical characteristics, mechanism and management of immune checkpoint inhibitor-related arthritis

Ravulizumab in NMOSD with Associated Interstitial Pneumonitis in a 59-Year-Old Female Patient: A Case Report

Influencing Factor Analysis and Prediction Model Construction of Dupilumab Treatment Adherence: A Prospective Cohort Study in Moderate-to-Severe Atopic Dermatitis

BUILDING ALLIANCES FOR EARLY DETECTION OF IMMUNODEFICIENCIES: FROM PRIMARY CARE TO HEMATOLOGY

Active LXR signaling, coupled with elevated mitochondrial and glycolytic metabolism contributes to GM-CSF–induced trained immunity

Regnase-1 in cDC1 Controls T Cell Priming and Shapes the Dynamics of Experimental Autoimmune Encephalomyelitis

Modulation of IRAK4 as a Therapeutic Strategy Against Monosodium Urate-and Xanthine-Induced Inflammation in Macrophages and HepG2 Cells

m-EASIX (better than EASIX) predicts severe CAR T-cell toxicities, worse Overall Survival, and discriminates Cytokine Release Syndrome from sepsis

Recent Advances on Hippo-YAP Pathway in Skin Diseases

GSDME in cardiovascular diseases: research system and contemporary progress

Comprehensive analysis of palmitoylation-related proteins for prognostic risk evaluation and tumor immune microenvironment assessment in glioma

Development and validation of immunotherapy nomogram for predicting the efficacy and prognosis of recurrent and metastatic cervical cancer

Gut microbiota metabolites in the immunoregulation of enteritis: research progress

Immunogenicity risk assessment of peptide-related impurities identified in generic teriparatide products

Significance and challenges of immunopharmacogenomics

A 20-year real-world study on drug survival and predictive factors for infliximab discontinuation in Behçet’s syndrome

Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in human and macaque

From immune suppression to immunotherapy sensitization: the dual roles of circRNAs in cancer progression