Frontiers in Immunology

Original Research

Published on 08 Dec 2025

Bystander CD8+ conventional memory versus virtual memory T cells in the initial days post-Trypanosoma cruzi infection

in Microbial Immunology

Maria Estefania Viano
Ruth Eliana Baigorri
Gastón Bergero
Maria Pilar Aoki
Nicolas Leonel Lidon
Maria Guadalupe Teixeira
Melisa Rocio Herrera
Claudia Cristina Motran
Fabio Marcelo Cerban
Cinthia Carolina Stempin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1674964

678 views

Editorial

Published on 08 Dec 2025

Editorial: Recent trends and advancements in multispectral and hyperspectral imaging for cancer detection

in Cancer Immunity and Immunotherapy

I-Chen Wu
Hsiang-Chen Wang
Arvind Mukundan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1752197

429 views

Systematic Review

Published on 08 Dec 2025

Granulomatous mastitis, erythema nodosum, and arthritis syndrome: a narrative review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Sheng-Guang Li
Jing Zhang
Ji Li
Lina Zhang
Yadan Zou
Ting Long
Ruohan Yu
Yanfeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1689710

507 views

Systematic Review

Published on 08 Dec 2025

Enhanced efficacy of lung cancer treatment with radiotherapy and immune checkpoint inhibitors without increased pneumonia risk: a systematic review and meta-analysis of randomized controlled trials

in Cancer Immunity and Immunotherapy

Wenjing Wang
Lisha Ye
Yun Chen
Huihui Li
Weimin Mao
Xiaoling Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685963

502 views

Review

Published on 08 Dec 2025

Cardiolipin’s multifaceted role in immune response: a focus on interacting proteins

in Molecular Innate Immunity

Zhuodong Chai
Yuqi Zhou
Sukria Hossain
Khanh Huynh
Sahelosadat Hajimirzaei
Yan Zhang
Jiaqian Qi
Guoying Zhang
Zhenyu Li
Yinan Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680326

591 views

Original Research

Published on 08 Dec 2025

Concentration monitoring and dose optimization for infliximab in Crohn’s disease patients: a machine learning-based covariate ensemble model

in Systems Immunology

Yuewen Chen
Shoutian Zhang
Si Chen
Shaojun Jiang
Shuifang Zhou
Jing Liu
Zhoujie Liu
Rongfang Lin
Jianwen Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1715241

524 views

Original Research

Published on 08 Dec 2025

SWI/SNF complex alterations predict immunotherapy response in bladder cancer

in Cancer Immunity and Immunotherapy

Jian Zhang
Yapeng Wang
Qian Yan
Haitao Wang
Qiang Ran
Hailin Zhu
Weiming Luo
Yangkun Ao
Ying-ang Ji
Jing Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1708324

538 views

Original Research

Published on 08 Dec 2025

Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Chenyi Shao
Yan Zhen
Nana Xia
Xueliang Zhang
Ninghui Yan
Mengmeng Zhou
Yiyuan Guo
Limin Tan
Qiang Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697803

465 views

Original Research

Published on 08 Dec 2025

Single-cell transcriptomics reveals systemic immune dysregulation in non-segmental vitiligo

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jialing Xiao
Xiaojuan Guo
Lingxue Gong
Qinhui Li
Kai Dong
Xiaoxin Guo
Huan Li
Ting Wang
Liang Wang
Weijia Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698566

771 views

Mini Review

Published on 08 Dec 2025

Development of human mycoplasma vaccines: navigating the IL-17A paradox

in Vaccines and Molecular Therapeutics

Wenjun Zhang
Tingting Li
Fangyi Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1720943

409 views

Editorial

Published on 08 Dec 2025

Editorial: Checkpoint immunotherapy: reshaping the landscape of gastrointestinal cancer treatment

in Cancer Immunity and Immunotherapy

Stavros P. Papadakos
Elias Kouroumalis
Georgios Germanidis
Stamatios Theocharis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1723645

443 views

Original Research

Published on 08 Dec 2025

Enhancing functional antibody responses against HIV envelope V1V2 through vaccine formulations

in Vaccines and Molecular Therapeutics

Clauvis Kunkeng Yengo
Xiaomei Liu
Gabriel Laghlali
Seok-Chan Park
Jéromine Klingler
Christina C. Luo
Xunqing Jiang
Xiang-Peng Kong
Priyanka G. Rao
Chitra Upadhyay

Frontiers in Immunology

doi 10.3389/fimmu.2025.1722596

708 views

Case Report

Published on 08 Dec 2025

Challenging manifestations of ANCA-associated vasculitis treated with avacopan: two case reports

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Aglaia Chalkia
Anastasia Politi
Isavella Tryfonos
Christos Koutsianas
Harikleia Gakiopoulou
Dimitrios Vassilopoulos
Dimitrios Petras

Frontiers in Immunology

doi 10.3389/fimmu.2025.1717889

446 views

Original Research

Published on 08 Dec 2025

Molecular transmission network characteristics and high-risk transmission analysis of newly reported HIV-1 subjects in Nantong, China

in Vaccines and Molecular Therapeutics

Dongyang Wang
Xiaoyi Zhou
Tianze Yuan
Hongli Xia
Kai Liu
Anni Chen
Ping Zhu
Xun Zhuang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1716273

497 views

Original Research

Published on 08 Dec 2025

A multi-omic machine learning approach deconstructs the role of amino acid metabolism in the immune microenvironment and prognosis of colon adenocarcinoma

in Cancer Immunity and Immunotherapy

Hua Zhong
Jiangdong Jin
Yi Zhang
Nuo Chen
Anya Liu
Chenfei Jiang
Wenbing Zhang
Zirui He

Frontiers in Immunology

doi 10.3389/fimmu.2025.1719555

342 views

Original Research

Published on 08 Dec 2025

Autoimmune cerebellopyramidal syndrome as a complex form of autoimmune cerebellar ataxia: a cohort study

in Multiple Sclerosis and Neuroimmunology

Mange Liu
Haitao Ren
Siyuan Fan
Le Zhang
Hongzhi Guan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1724439

356 views

Original Research

Published on 08 Dec 2025

Novel nanobody-161 binds tumor necrosis factor receptor 2 (TNFR2) to exert an anti-tumor effect but does not block TNFα-binding

in Cancer Immunity and Immunotherapy

Liang Huang
Chao Kong
Yuhao Hu
Michael Zhang
Shuangqi Li
Wanjing Wang
Hui Guan
Mei Ling Lim
Zhen Zhang
Wenhai Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1694313

627 views

Original Research

Published on 08 Dec 2025

SCPEP1+ basal cells are associated with the remodeling of oxidative stress signaling networks in idiopathic pulmonary fibrosis

in Inflammation

Xiang Zhou
Tong Lu
Ran Xu
Chenghao Wang
Simiao Chen
Jing Chen
Xiaoyan Chang
Meifeng Li
Jiaxin Shi
Chengyu Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676086

687 views

Original Research

Published on 08 Dec 2025

Multi-omics spatial characteristics of CD8+TRM cells in hepatocellular carcinoma and immunotherapy response prediction

in Cancer Immunity and Immunotherapy

Shipeng Li
Ju Ma
Xinqiang Li
Bingbing Qiao
Liancai Wang
Deyu Li
Hua Zhou
Haixu Xu
Jinzhen Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1710741

504 views

Review

Published on 08 Dec 2025

Gut microbiome, a novel precision medicine biomarker for hepatocellular carcinoma

in Microbial Immunology

Pin-Jung Chen
Suzanne Devkota
Stephen Shiao
Andrew Hendifar
Ju Dong Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568962

434 views

Case Report

Published on 08 Dec 2025

Successful ECMO support for cardiogenic shock induced by immune checkpoint inhibitor-associated myocarditis: a case report and literature review

in Cancer Immunity and Immunotherapy

Yujing Zhang
Ruiting Li
Yongxiang Jiang
Shengwen Sun
Yin Yuan
You Shang
Huaqing Shu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646040

466 views

Review

Published on 08 Dec 2025

Cancer stem cells in hepatocellular carcinoma: therapy resistance and emerging treatments

in Cancer Immunity and Immunotherapy

Dipesh Kumar Yadav
Rajesh Kumar Yadav
Alina Singh
Yi Huang
Dandan Bao
Zhangwei Yang
Hanzhang Huang
Yin Jiang
Pengwei Wang
Sisi Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1704868

563 views

Original Research

Published on 08 Dec 2025

Whole transcriptome analysis and preliminary construction of ceRNA networks in obstetric antiphospholipid syndrome

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Lan Zhang
Tingting Dong
Xiaoyu Ji
Pengzheng Chen
Xietong Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663849

279 views

Review

Published on 08 Dec 2025

Multi-omics-driven biomarker discovery in autoimmune diseases: a comprehensive review

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Yi Zhang
Haofeng Xu
Lijuan Xu
Shasha Jiang
Yan Yu
Heping Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652211

523 views

48,462 articles

articles

Bystander CD8+ conventional memory versus virtual memory T cells in the initial days post-Trypanosoma cruzi infection

Editorial: Recent trends and advancements in multispectral and hyperspectral imaging for cancer detection

Granulomatous mastitis, erythema nodosum, and arthritis syndrome: a narrative review

Enhanced efficacy of lung cancer treatment with radiotherapy and immune checkpoint inhibitors without increased pneumonia risk: a systematic review and meta-analysis of randomized controlled trials

Cardiolipin’s multifaceted role in immune response: a focus on interacting proteins

Concentration monitoring and dose optimization for infliximab in Crohn’s disease patients: a machine learning-based covariate ensemble model

SWI/SNF complex alterations predict immunotherapy response in bladder cancer

Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD

Single-cell transcriptomics reveals systemic immune dysregulation in non-segmental vitiligo

Development of human mycoplasma vaccines: navigating the IL-17A paradox

Editorial: Checkpoint immunotherapy: reshaping the landscape of gastrointestinal cancer treatment

Enhancing functional antibody responses against HIV envelope V1V2 through vaccine formulations

Challenging manifestations of ANCA-associated vasculitis treated with avacopan: two case reports

Molecular transmission network characteristics and high-risk transmission analysis of newly reported HIV-1 subjects in Nantong, China

A multi-omic machine learning approach deconstructs the role of amino acid metabolism in the immune microenvironment and prognosis of colon adenocarcinoma

Autoimmune cerebellopyramidal syndrome as a complex form of autoimmune cerebellar ataxia: a cohort study

Novel nanobody-161 binds tumor necrosis factor receptor 2 (TNFR2) to exert an anti-tumor effect but does not block TNFα-binding

SCPEP1+ basal cells are associated with the remodeling of oxidative stress signaling networks in idiopathic pulmonary fibrosis

Multi-omics spatial characteristics of CD8+TRM cells in hepatocellular carcinoma and immunotherapy response prediction

Gut microbiome, a novel precision medicine biomarker for hepatocellular carcinoma

Successful ECMO support for cardiogenic shock induced by immune checkpoint inhibitor-associated myocarditis: a case report and literature review

Cancer stem cells in hepatocellular carcinoma: therapy resistance and emerging treatments

Whole transcriptome analysis and preliminary construction of ceRNA networks in obstetric antiphospholipid syndrome

Multi-omics-driven biomarker discovery in autoimmune diseases: a comprehensive review