Frontiers in Immunology | Cancer Immunity and Immunotherapy

Original Research

Published on 19 Jun 2025

SNRPB2 facilitates esophageal squamous cell carcinoma oncogenesis and progression via E2F4 stabilization

in Cancer Immunity and Immunotherapy

Feng Xu
Chen-Cheng Zhu
Chen Lu
Guang-Yao Ning
Ren-Quan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610721

152 views

Review

Published on 19 Jun 2025

Exosomal proteins: new targets for early diagnosis and treatment of cancer

in Cancer Immunity and Immunotherapy

Haibin Shen
Meijin Liu
Wentai Yang
Dewang Xiao
Zongbo Peng
Dingyu Rao
Defa Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613494

Original Research

Published on 19 Jun 2025

Comprehensive analysis of RFC4 as a potential biomarker for regulating the immune microenvironment and predicting immune therapy response in lung adenocarcinoma

in Cancer Immunity and Immunotherapy

Jianqing Zheng
Na Lin
Bifen Huang
Min Wu
Lihua Xiao
Bingwei Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578243

561 views

Review

Published on 19 Jun 2025

PLK1 in cancer therapy: a comprehensive review of immunomodulatory mechanisms and therapeutic opportunities

in Cancer Immunity and Immunotherapy

Weihao Wang
Rui Zhao
Yahui Wang
Liying Pan
Fang Luan
Guobin Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602752

177 views

Review

Published on 19 Jun 2025

CAR-T cell therapy in brain malignancies: obstacles in the face of cellular trafficking and persistence

in Cancer Immunity and Immunotherapy

Serge Yaacoub
Elton Vannoy
Stefanyda Maslova
Abigail Haffey
Khatereh Khorsandi
Natasha Sheybani
Dalia Haydar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596499

222 views

Original Research

Published on 19 Jun 2025

Expression patterns of estrogen and androgen receptors in NSCLC patients according to the PD-L1 profile

in Cancer Immunity and Immunotherapy

Vianey Rodriguez-Lara
Gala Cortés-Ramírez
Itzel Amayrani Angeles-Torres
Jeronimo Rodriguez-Cid
Sally María Luisa Pedraza-Reyes
Maria Rosa Avila-Costa
José Luis Ordoñez-Librado
Marco Cerbón

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602579

250 views

Review

Published on 19 Jun 2025

The role of MCT1 in tumor progression and targeted therapy: a comprehensive review

in Cancer Immunity and Immunotherapy

Zheng Xu
Xuemei Wang
Hongjing Cheng
Jiuling Li
Xin Zhang
Xueju Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610466

Case Report

Accepted on 18 Jun 2025

Case Report: CAR-T Therapy for Primary Cerebellar ALK-Negative Anaplastic Large Cell Lymphoma

in Cancer Immunity and Immunotherapy

qing Zhong Zou
han Si Lai
Hai Yi
Qian Zhang
Hao Yao
Hui Yang
Ling Zhang
ALEX H CHANG
Yi Su
Jin Rao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570214

Original Research

Accepted on 18 Jun 2025

The pyroptosis-related gene signature predicts prognosis and reveals immune microenvironment infiltration in reclassified glioblastoma based on 2021 WHO classification

in Cancer Immunity and Immunotherapy

XiaoHong Zheng
Zhangchi Pan
Lina Chen
Can Wang
Wenbin Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617036

Editorial

Accepted on 18 Jun 2025

Editorial:Mitochondrial damage interacts with the immune system and tumor microenvironment

in Cancer Immunity and Immunotherapy

Weihong Guo
Haihong Fang
Xundong Lin
Xin Yuan
Yiheng Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646413

Original Research

Accepted on 18 Jun 2025

Targeting the KLF5/PI3K/AKT axis as a therapeutic strategy to overcome neoadjuvant chemoresistance in colorectal cancer

in Cancer Immunity and Immunotherapy

Meiling Gao
Jiahao Qian
Ping Xia
Wancheng Liu
Yunjia Jiang
Yuchang Xia
Xin Yao
Qingqing Jiao
Minggang Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593639

Systematic Review

Accepted on 18 Jun 2025

Immune hemolytic anemia associated with the use of immune checkpoint inhibitors: a scoping review

in Cancer Immunity and Immunotherapy

Juan-Manuel Hernandez-Martinez
Eduardo Rios-Garcia
Cittim B Palomares-Palomares
Oscar Arrieta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586426

Original Research

Published on 18 Jun 2025

Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics

in Cancer Immunity and Immunotherapy

Umair Ali Khan Saddozai
Chenxu Liu
Fei Yan
Zhendong Lu
Muhammad Babar Khawar
Muhammad Usman Akbar
Saadullah Khattak
Haibo Sun
Ping Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586544

260 views

Original Research

Published on 18 Jun 2025

PABPN1 as a pan-cancer biomarker: prognostic significance and association with tumor immune microenvironment

in Cancer Immunity and Immunotherapy

Hong-Xing Li
Xiao-Ling Ma
Wang-bin Ma
Tian-Yu Jia
Xiao-Hong Sun
Xiao-Xia He
Li-li Zhang
Ya-Ming Xi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1553527

211 views

Review

Published on 18 Jun 2025

Intratumoral immunotherapy prior to cancer surgery, a promising therapeutic approach

in Cancer Immunity and Immunotherapy

Kevine Silihe Kamga
Steven Fiering

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545000

431 views

Review

Published on 18 Jun 2025

Prostate cancer immunotherapy-based strategies: an updated review emphasizing immune checkpoint inhibitors

in Cancer Immunity and Immunotherapy

Hua Lu
Zhaojun Teng
Jiajia Wang
Wenchao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583363

282 views