Frontiers in Immunology | Comparative Immunology

Original Research

Published on 10 Oct 2025

Characterization of T-cell immune responses against Staphylococcus chromogenes naturally-induced subclinical mastitis in dairy cows

in Comparative Immunology

Chen Yu
Jie Wu
Sheng Zhang
Chunmei Ye
Guojun Wei
Zhangping Yang
Zhipeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679963

925 views

Original Research

Accepted on 09 Oct 2025

Study on the regulatory role of MINK1 gene in the activation of NLRP3 inflammasome in common carp (Cyprinus carpio L.)

in Comparative Immunology

Rongrong Liu
Keying Zhao
Yue Zhao
Guiwen Yang
Hua Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663527

Original Research

Published on 08 Oct 2025

Genetic reinstatement of RIG-I in chickens reveals insights into avian immune evolution and influenza interaction

in Comparative Immunology

Hicham Sid
Theresa von Heyl
Sabrina Schleibinger
Romina Klinger
Leah Heymelot Nabel
Hanna Vikkula
Rodrigo Guabiraba
Vanaique Guillory
Ryan Scicluna
Mohanned Naif Alhussien

Frontiers in Immunology

doi 10.3389/fimmu.2025.1680791

847 views

Original Research

Published on 08 Oct 2025

A novel role for Hsc70–4 in blood cell differentiation in Drosophila

in Comparative Immunology

Bayan Kharrat
Erika Gábor
Péter Vilmos
Lauren M. Goins
Viktor Honti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641695

932 views

Original Research

Published on 07 Oct 2025

Anti-inflammatory mechanism of total flavonoids from Polygala fallax Hemsl. based on network pharmacology, molecular docking, and experimental validation

in Comparative Immunology

Chunhong Liao
Hua Su
Fengzhen Li
Chenglong Wang
Sufang Yang
Zujie Qin
Ning Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690388

1,206 views

Original Research

Accepted on 06 Oct 2025

Early allergen introduction overrides allergy predisposition in offspring of horses with Culicoides hypersensitivity

in Comparative Immunology

Elisabeth Simonin
Sigurbjorg Torsteinsdóttir
Vilhjálmur Svansson
Sigríður Björnsdóttir
Heather Freer
Justine Tarsillo
Bettina Wagner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654693

Original Research

Published on 06 Oct 2025

Differential perception of virulence factors of uropathogenic Escherichia coli at the level of chromatin dynamics of infected host cells

in Comparative Immunology

Krishnendu Mukherjee
Wiebke Aschenbach
Annika Hilger
Judith Saur
Ulrich Dobrindt

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642683

726 views

Original Research

Accepted on 03 Oct 2025

Dermal fibroblast cultures recapitulate differences between deermice and mice in responses to a Toll-like receptor agonist

in Comparative Immunology

Jonathan V. Duong
Aqsa Motiwala
William H. Hotz
Landen Gozashti
Anthony D. Long
Alan G Barbour

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666789

123 views

Original Research

Published on 02 Oct 2025

Bulk and single-cell transcriptome profiling reveals the dynamic immune response in granulomatous amebic encephalitis caused by Balamuthia mandrillaris: a cohort study

in Comparative Immunology

Jingjia Zhang
Xinmiao Jia
Bin Yang
Ying Ge
Wei Jiang
Yang Cong
Huanwen Wu
Huifang Liu
Jingjing Tian
Yingchun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1677014

1,384 views

Original Research

Published on 01 Oct 2025

High-content stimulated Raman pathology imaging and transcriptomics reveal leukemia subtype-specific lipid metabolic heterogeneity

in Comparative Immunology

Xuelian Cheng
Jing Liu
Ming Chen
Haoyu Wang
Shuxu Dong
Yuan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662281

938 views

Original Research

Published on 30 Sep 2025

Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum

in Comparative Immunology

Diana L. Pacheco-Olvera
Stephanie Saint Remy-Hernández
E. Ernestina Godoy-Lozano
Juan Téllez-Sosa
Humberto Valdovinos-Torres
Everado Curiel-Quesada
Constantino López-Macías
Jesus Martínez-Barnetche

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656386

1,203 views

Review

Accepted on 29 Sep 2025

Neutrophil and Neutrophil extracellular traps in acute kidney injury: From mechanisms to treatments

in Comparative Immunology

Yifei Fu
Wang Wenjuan
Na Gong
Xumin Zheng
Xinru Guo
Kaiting Zhuang
Qiuxia Han
Feng Zhe
Xiangmei Chen
GUANGYAN CAI

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688207

427 views

Original Research

Accepted on 29 Sep 2025

Marburg and Sudan viruses elicit divergent interferon responses and cytokine storm signaling in Egyptian rousette bat macrophages

in Comparative Immunology

Ivet A. Yordanova
Catherine E. Arnold
Nicolas Corrales
Jonathan C. Guito
Angelika Lander
Lay Teng Ang
Jonathan S. Towner
Joseph B. Prescott

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686343

404 views

Original Research

Published on 29 Sep 2025

Resveratrol suppresses OSCC invasion and migration by regulating macrophage polarization via Syk signaling pathway

in Comparative Immunology

Weibo Li
Ying Qi
Yafei Li
Lu Liu
Xiaodan Dong
Bo Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1660851

842 views

Original Research

Accepted on 26 Sep 2025

The evolutionary history of IGKC in mammals reveals ancient duplications and remarkable divergence in lagomorphs

in Comparative Immunology

Ana Pinheiro
J. Ricardo Borges
João Pedro Marques
Pedro Jose Esteves

Frontiers in Immunology

doi 10.3389/fimmu.2025.1686094

860 views

Original Research

Published on 25 Sep 2025

Metformin-associated gut microbiota remodeling correlates with reinvigorated splenic immunity in aged mice: microbiome-immune crosstalk via the gut-spleen axis

in Comparative Immunology

Shu-Qin Ding
Xin-Yi Lyu
Shi-Yu Zhou
Yi-Wan Fang
Hao-Xin Ji
Jiang-Yan Li
He-Zuo Lü

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633486

3,823 views