Frontiers in Immunology | Comparative Immunology

Original Research

Published on 04 Mar 2026

Cloning, expression and characterisation of antigen-specific recombinant bat immunoglobulin from the black flying fox (Pteropus alecto)

in Comparative Immunology

Jun Jet Hen
Ariel Isaacs
Benjamin Liang
Tony Schountz
Keith Chappell
Paul R. Young
Naphak Modhiran
Daniel Watterson

Frontiers in Immunology

doi 10.3389/fimmu.2026.1743193

180 views

Original Research

Published on 04 Mar 2026

The involvement of miRNAs in the enhanced immune response of oysters via haemocyte-mediated immune priming

in Comparative Immunology

Xiaoxu Zhou
Lixin Guo
Weilin Wang
Lingyuan Song
Yuefeng Dai
Jiajun Zuo
Lingling Wang
Linsheng Song

Frontiers in Immunology

doi 10.3389/fimmu.2026.1753252

Original Research

Published on 04 Mar 2026

A single-cell immune atlas of primary and secondary lymphoid organs in pigs

in Comparative Immunology

Jayne E. Wiarda
Muskan Kapoor
Sathesh K. Sivasankaran
Kristen A. Byrne
Crystal L. Loving
Christopher K. Tuggle

Frontiers in Immunology

doi 10.3389/fimmu.2026.1704257

176 views

Original Research

Published on 03 Mar 2026

Targeting Toll-like Receptor 2: synthetic diacylated lipopeptides polarize equine macrophages towards a pro-inflammatory phenotype

in Comparative Immunology

Chiara Grazia De Ciucis
Floriana Fruscione
Filippo Dell’Anno
Susanna Zinellu
Emanuela Giaconi
Simone Loi
Nicolò Columbano
Giulia Franzoni
Elisabetta Razzuoli

Frontiers in Immunology

doi 10.3389/fimmu.2026.1720816

108 views

Original Research

Accepted on 02 Mar 2026

UVB-Induced Genotoxic Stress Activates the DNA Damage Response and Innate Immune Pathways in Sea Urchin Coelomocytes

in Comparative Immunology

Riss M Kell
Margaret K Weber
Rosa Y Escalante
Jeffrey C Silva
Andrea G Bodnar

Frontiers in Immunology

Correction

Accepted on 26 Feb 2026

Comparing the Performance of Radiomics, Nomograms, Machine Learning, and Large Language Models in Predicting 28-Day Mortality in Severe Community-Acquired Pneumonia Patients

in Comparative Immunology

Tingting Lin
Huimin Wan
Yifei Liang
Jie Ming
Jingjing Lu
Zhongliang Guo

Frontiers in Immunology

Original Research

Published on 26 Feb 2026

Changes in gene regulation are associated with the evolution of resistance to a novel parasite

in Comparative Immunology

Lauren E. Fuess
Amanda K. Hund
Mariah L. Kenney
Meghan F. Maciejewski
Joseph M. Marini
Daniel I. Bolnick

Frontiers in Immunology

doi 10.3389/fimmu.2026.1697157

433 views

Original Research

Published on 26 Feb 2026

Transcriptomic and proteomic analyses of the immune responses of C-type lectin from Conogethes punctiferalis against fungal infection

in Comparative Immunology

Shaohua Li
Zhiwei Kang
Xiangdong Li
Hailei Wei
Xiangchu Yin
Fanghua Liu
Fangqiang Zheng

Frontiers in Immunology

doi 10.3389/fimmu.2026.1774776

420 views

Review

Published on 25 Feb 2026

Muscling in on immunity: the role of muscle in the insect immune response, demonstrating the value of a whole organism perspective

in Comparative Immunology

Shelley A. Adamo

Frontiers in Immunology

doi 10.3389/fimmu.2026.1749942

150 views

Original Research

Accepted on 23 Feb 2026

Mitigating combined toxic effects of arsenic, ammonia, and high temperature through dietary Iron in fish

in Comparative Immunology

Neeraj Kumar
Paritosh Kumar
KOTHA SAMMI REDDY

Frontiers in Immunology

Brief Research Report

Published on 23 Feb 2026

An update on the characterization of immunoglobulin loci in Ambystoma mexicanum

in Comparative Immunology

Stephanie Saint Remy-Hernández
Diana Laura Pacheco-Olvera
Elizabeth Ernestina Godoy-Lozano
Juan Miguel-Ruiz
Juan Téllez-Sosa
Humberto Valdovinos-Torres
Nancy Rivas
Constantino López-Macías
Jesús Martínez-Barnetche

Frontiers in Immunology

doi 10.3389/fimmu.2026.1736245

408 views

Original Research

Published on 18 Feb 2026

External immune sentinels in the seawater ecosystem: the specialization of bivalve hemocytes

in Comparative Immunology

Magalí Rey-Campos
Amaro Saco
Antonella Panebianco
Judit Castro
Alejandro Romero
Beatriz Novoa
Antonio Figueras

Frontiers in Immunology

doi 10.3389/fimmu.2026.1765948

379 views

Original Research

Accepted on 17 Feb 2026

Transcriptomic insights into the immune responses of the lung and muscle of non-healthy harbor porpoises (Phocoena phocoena)

in Comparative Immunology

Eda Merve Dönmez
Andrej Fabrizius
Ursula Siebert, Prof. Prof. H. C. Doc

Frontiers in Immunology

Review

Published on 12 Feb 2026

Identification of Drosophila melanogaster as a model organism in COPD research

in Comparative Immunology

Yuan Zhang
Jing Kou
Yuxuan Zhang
Haiyi Huang
Yang Yang
Chengshuang Liu
Ting Lu
Xiaoxuan Zhao
Yongqi Liu
Jianzheng He

Frontiers in Immunology

doi 10.3389/fimmu.2026.1707110

574 views

Review

Published on 12 Feb 2026

A new type of biomarker for heat stress: insights from immunology

in Comparative Immunology

Chunmei Ye
Zhipeng Zhang
Zhangping Yang

Frontiers in Immunology

doi 10.3389/fimmu.2026.1742202

502 views

Original Research

Accepted on 10 Feb 2026

IgM-mediated protection drives early B-cell activation and mucosal containment of Vibrio anguillarum in Atlantic cod (Gadus morhua)

in Comparative Immunology

Naomi Croft Guslund
Alexandra Jonsson
Anders Kristian Krabberød
Adrian Lopez Porras
Simen Nørstebø
Rune Henning Sørum
Kjetill S JakobseJ
Finn-Eirik Johansen
Shuo-Wang Qiao

Frontiers in Immunology

326 views

Original Research

Published on 10 Feb 2026

A novel oral immunotherapy strategy using transgenic barley induces Culicoides allergen-specific immune responses in horses

in Comparative Immunology

Fenja Johanna von der Höden
Sara Björk Stefansdottir
Sigurbjörg Torsteinsdottir
Vilhjalmur Svansson
Jon Mar Björnsson
Bettina Wagner
Dorontina Mahmuti
Eliane Marti
Sigridur Jonsdottir

Frontiers in Immunology

doi 10.3389/fimmu.2026.1774358

624 views

Original Research

Published on 10 Feb 2026

Chicken IRF10 suppresses the cGAS-STING-IFN antiviral signaling pathway by targeting IRF7

in Comparative Immunology

Sen Jiang
Jingyu He
Kun Wang
Mengjia Lv
Hongjian Han
Bingjie Sun
Nanhua Chen
Wanglong Zheng
Jianzhong Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2026.1767491

421 views

Editorial

Published on 09 Feb 2026

Editorial: Immunomics in aquaculture: deciphering the immune landscape of aquacultured animals through omics technologies

in Comparative Immunology

Jorge Galindo-Villegas
Patricia Pereiro

Frontiers in Immunology

doi 10.3389/fimmu.2026.1788094

517 views

Review

Published on 05 Feb 2026

Unique chicken B cell development: species-specific mechanisms and contradictory requirements of B cell receptor for post-hatched B cell development

in Comparative Immunology

Seung Je Woo
Thirubasyini Songodan
Jae Yong Han

Frontiers in Immunology

doi 10.3389/fimmu.2026.1755331

742 views

Original Research

Published on 05 Feb 2026

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle Tenebrio molitor L.

in Comparative Immunology

Natalia Konopińska
Karolina Walkowiak-Nowicka
Grzegorz Nowicki
Maryam Keshavarz
Szymon Chowański
Jens Rolff
Arkadiusz Urbański

Frontiers in Immunology

doi 10.3389/fimmu.2026.1725225

639 views
1 citation

Original Research

Published on 04 Feb 2026

Contrasted modifications of IgM and IgT repertoires induced by high- and low-virulent infectious pancreatic necrosis virus strains in rainbow trout (Oncorhynchus mykiss)

in Comparative Immunology

Sofie Navelsaker Thommessen
Luc Jouneau
Rosario Castro
Vanessa Mhanna
Encarnita Mariotti-Ferrandiz
Hetron M. Munang´andu
Amr Ahmed Abdelrahim Gamil
Bertrand Collet
Pierre Boudinot
Oystein Evensen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690504

717 views

Original Research

Published on 03 Feb 2026

NOD-like receptor repertoire in the chromosome-level genome of the demosponge Dysidea avara (Schmidt, 1862)

in Comparative Immunology

Vasiliki Koutsouveli
Montserrat Torres-Oliva
Angela M. Marulanda-Gomez
Andre Franke
Janina Fuß
Ruth A. Schmitz
Ute Hentschel
Thorsten B. H. Reusch
Lucía Pita

Frontiers in Immunology

doi 10.3389/fimmu.2026.1725140

810 views

Original Research

Published on 30 Jan 2026

Mechanistic investigation into the differences in growth performance and resistance to spring viremia of carp virus in common carp

in Comparative Immunology

Kai Lei
Qiang Li
Jian Zhou
Yong-Qiang Deng
Ping Ouyang
Yang Feng
Sen-Yue Liu
Yan Liu
Hua Ye
Cheng-Yan Mou

Frontiers in Immunology

doi 10.3389/fimmu.2026.1721974

607 views

1,458 articles

articles

Cloning, expression and characterisation of antigen-specific recombinant bat immunoglobulin from the black flying fox (Pteropus alecto)

The involvement of miRNAs in the enhanced immune response of oysters via haemocyte-mediated immune priming

A single-cell immune atlas of primary and secondary lymphoid organs in pigs

Targeting Toll-like Receptor 2: synthetic diacylated lipopeptides polarize equine macrophages towards a pro-inflammatory phenotype

UVB-Induced Genotoxic Stress Activates the DNA Damage Response and Innate Immune Pathways in Sea Urchin Coelomocytes

Comparing the Performance of Radiomics, Nomograms, Machine Learning, and Large Language Models in Predicting 28-Day Mortality in Severe Community-Acquired Pneumonia Patients

Changes in gene regulation are associated with the evolution of resistance to a novel parasite

Transcriptomic and proteomic analyses of the immune responses of C-type lectin from Conogethes punctiferalis against fungal infection

Muscling in on immunity: the role of muscle in the insect immune response, demonstrating the value of a whole organism perspective

Mitigating combined toxic effects of arsenic, ammonia, and high temperature through dietary Iron in fish

An update on the characterization of immunoglobulin loci in Ambystoma mexicanum

External immune sentinels in the seawater ecosystem: the specialization of bivalve hemocytes

Transcriptomic insights into the immune responses of the lung and muscle of non-healthy harbor porpoises (Phocoena phocoena)

Identification of Drosophila melanogaster as a model organism in COPD research

A new type of biomarker for heat stress: insights from immunology

IgM-mediated protection drives early B-cell activation and mucosal containment of Vibrio anguillarum in Atlantic cod (Gadus morhua)

A novel oral immunotherapy strategy using transgenic barley induces Culicoides allergen-specific immune responses in horses

Chicken IRF10 suppresses the cGAS-STING-IFN antiviral signaling pathway by targeting IRF7

Editorial: Immunomics in aquaculture: deciphering the immune landscape of aquacultured animals through omics technologies

Unique chicken B cell development: species-specific mechanisms and contradictory requirements of B cell receptor for post-hatched B cell development

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle Tenebrio molitor L.

Contrasted modifications of IgM and IgT repertoires induced by high- and low-virulent infectious pancreatic necrosis virus strains in rainbow trout (Oncorhynchus mykiss)

NOD-like receptor repertoire in the chromosome-level genome of the demosponge Dysidea avara (Schmidt, 1862)

Mechanistic investigation into the differences in growth performance and resistance to spring viremia of carp virus in common carp