Frontiers in Immunology

Original Research

Published on 05 Jun 2025

Integrated machine learning and single-cell RNA sequencing reveal COL4A2 and CXCL6 as oxidative stress-associated biomarkers in periodontitis

in Inflammation

Siyu Sun
Jing Ren
Xiujuan Zeng
Yanbin Chen
Qianbing Zhou
Junying Yang
Shan Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598642

458 views

Original Research

Published on 05 Jun 2025

Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis of health insurance claims in Japan

in Inflammation

Hiroyuki Koami
Yutaro Furukawa
Yuri Hirota
Akira Sasaki
Hirotaka Ogawa
Ayaka Matsuoka
Kota Shinada
Kento Nakayama
Ryota Sakurai
Sachiko Iwanaga

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601690

332 views

Original Research

Accepted on 04 Jun 2025

Cannabinoids and Alcohol Co-Exposure Modulate Pathogen-Induced Pulmonary Immune Responses

in Inflammation

DeJana Parker
Vijay Sivaraman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539813

Review

Accepted on 04 Jun 2025

The Myeloid Switch: Immune Drivers in Atopic Dermatitis -Roles in Pathogenesis and Emerging Therapeutic Targeting

in Inflammation

Erik Kupschke
Mirjam Schenk

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608338

109 views

Original Research

Accepted on 04 Jun 2025

circ-0001875 downregulation is associated with M1 macrophage activation and lung inflammation in severe asthma

in Inflammation

Gege Liu
Jiahao Cao
Yiyan Lin
Bingyu Long
Yanyu Su
Guiqiang Qiu
Chi Jiang
Yue Wang
Xuanna Zhao
Dan Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601272

Original Research

Published on 04 Jun 2025

Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea

in Inflammation

Yue Song
Jinxia Ni
Jingxue Yuan
Ziniu Zhang
Dinghao Wang
Zhihao Xiong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563626

689 views

Original Research

Published on 04 Jun 2025

Partial depletion of circulating neutrophil granulocytes in mice exacerbates the inflammatory response and hypothermia during LPS induced severe systemic inflammation

in Inflammation

Jessica Hernandez
Fabian Johannes Pflieger
Julia Schäffer
Leona Bähr
Jenny Schneiders
Thomas Reichel
Marita Meurer
Benjamin Lamp
Natali Bettina Bauer
Karsten Krüger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578590

512 views

Review

Published on 04 Jun 2025

KLF feedback loops in innate immunity

in Inflammation

Jessica M. Salmon
Holly Adams
Graham W. Magor
Andrew C. Perkins

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606277

368 views

Original Research

Published on 04 Jun 2025

Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice

in Inflammation

Micah L. Willis
Roland F. Seim
Laura E. Herring
Angie L. Mordant
Thomas S. Webb
Gilbert R. Upchurch
Ashish K. Sharma
Bruce A. Cairns
Philip A. Efron
Shannon M. Wallet

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596598

299 views

Mini Review

Accepted on 03 Jun 2025

Harnessing Extracellular Vesicles to Tame Inflammation: A New Strategy for Atherosclerosis Therapy

in Inflammation

Jiawei Li
Tianliang Wen
Xiaoran Li
Ruoyao Cheng
Junyi Shen
Xin Wang
Zhaoqi Guo
Zhengjie Teng
Lin Yi
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625958

100 views

Original Research

Accepted on 03 Jun 2025

VISTA Acts as a Protective Immune Checkpoint in Indirect Acute Respiratory Distress Syndrome by Modulating Systemic and Compartmentalized Inflammation

in Inflammation

Baoji Hu
Jihong Jiang
Chun-Shiang Chung
Chyna Gray
Yaping Chen
Jianrong Guo
Alfred Ayala

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618135

Original Research

Accepted on 03 Jun 2025

Hs-CRP/HDL-C Ratio as a Predictive Inflammatory-Lipid Marker for Sarcopenia: Evidence from NHANES 2015-2018

in Inflammation

Xin-Yan Guo
Li Liang-Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600421

123 views

Review

Accepted on 03 Jun 2025

TGF-β Inhibitors: the Future for Prevention and Treatment of Liver Fibrosis?

in Inflammation

Weili Wang
Yilin Gao
Yizhen Chen
Meng Cheng
Yonghao Sang
Liuting Wei
Rong Dai
Yiping Wang
Lei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583616

250 views

Mini Review

Accepted on 03 Jun 2025

Role of Macrophages in Neuroimmune Regulation

in Inflammation

Hairong Xiao
Kai Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573174

Original Research

Accepted on 03 Jun 2025

Single-cell atlas of human skin implicates APOE pro-inflammatory signaling in diabetic foot ulcers

in Inflammation

Yating Yin
Li Li
Mingen Liu
Bin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591944

122 views

Brief Research Report

Published on 03 Jun 2025

The role of major allergens Art v 1 and Art v 3 in Artemisia pollen-induced asthma: a mouse model study

in Inflammation

Nazugum Akhtemova
Akbota Sergazina
Turlan Bolatbekov
Guliza Rakhmatullayeva
Elmira Tailakova
Kairat Tabynov
Gleb Fomin
Lan Zhao
Zhongshan Gao
Kaissar Tabynov

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590791

565 views