Frontiers in Immunology

Original Research

Published on 15 Apr 2025

Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model

in Inflammation

Qinghong Ma
Xincheng Feng
Yongxin Chen
Jue Zhang
Chao Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1541577

2,968 views
4 citations

Original Research

Published on 14 Apr 2025

Establishment of fracture blister model and analysis of plasma protein markers in rats

in Inflammation

Xin Hu
Peiyuan Wang
Tao Wang
Jingcheng Cao
Kezheng Du
Marius M. Scarlat
Lin Liu
Yutong Li
Xin Wang
Haofei Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547491

2,052 views

Review

Published on 14 Apr 2025

Targeting the immuno-inflammatory-microbial network: a key strategy for sepsis treatment

in Inflammation

Yue Xu
Jiaxin Wang
Rui Yuan
Zhu Qin
Kunlan Long
Peiyang Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575516

5,011 views
7 citations

Original Research

Published on 14 Apr 2025

MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro

in Inflammation

Ala’ Alhendi
Saleh A. Naser

Frontiers in Immunology

doi 10.3389/fimmu.2025.1562100

3,394 views

Review

Published on 11 Apr 2025

The role of ubiquitination and deubiquitination in the pathogenesis of non-alcoholic fatty liver disease

in Inflammation

Lihui Zhang
Sutong Liu
Qing Zhao
Xiaoyan Liu
Qiang Zhang
Minghao Liu
Wenxiao Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535362

4,739 views
6 citations

Original Research

Published on 10 Apr 2025

Acute myeloid leukemia-derived extracellular vesicles induced DNA methylation changes responsible for inflammatory program in normal hematopoietic stem progenitor cells

in Inflammation

Daniela Lamorte
Giovanni Calice
Stefania Trino
Michele Santodirocco
Antonella Caivano
Luciana De Luca
Ilaria Laurenzana

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569159

3,539 views
1 citation

Mini Review

Published on 10 Apr 2025

Advances in cell therapy for orthopedic diseases: bridging immune modulation and regeneration

in Inflammation

Jing Wang
Shenghao Xu
Bo Chen
Yanguo Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567640

6,213 views
6 citations

Case Report

Published on 10 Apr 2025

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

in Inflammation

Lital Remez-Gabay
Olga Vdovich
Luiza Akria
Etty Kruzel-Davila

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567999

3,256 views
1 citation

Original Research

Published on 08 Apr 2025

Ferroptosis-related protein biomarkers for diagnosis, differential diagnosis, and short-term mortality in patients with sepsis in the intensive care unit

in Inflammation

Zhangrui Zeng
Jie Deng
Gang Wang
Zixiang Luo
Weijia Xiao
Wenchao Xie
Jinbo Liu
Ke Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528986

4,231 views
4 citations

Review

Published on 08 Apr 2025

Understanding chronic inflammation: couplings between cytokines, ROS, NO, Cai2+, HIF-1α, Nrf2 and autophagy

in Inflammation

Krzysztof Piotr Michalak
Amelia Zofia Michalak

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558263

11,023 views
42 citations

Review

Published on 08 Apr 2025

Spinal neuron-glial crosstalk and ion channel dysregulation in diabetic neuropathic pain

in Inflammation

Jie Wu
Haijun Hu
Xi Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480534

5,902 views
6 citations

Brief Research Report

Published on 08 Apr 2025

Macrophage caspase-8 inhibition accelerates necrotic core expansion in atheroma plaque in mice

in Inflammation

Thomas Pilot
Stéphanie Solier
Antoine Jalil
Charlène Magnani
Tom Vanden Berghe
Peter Vandenabeele
David Masson
Eric Solary
Charles Thomas

Frontiers in Immunology

doi 10.3389/fimmu.2025.1513637

3,428 views
3 citations

Mini Review

Published on 07 Apr 2025

NLRP3 inflammasome in Alzheimer’s disease: molecular mechanisms and emerging therapies

in Inflammation

Zhitao Li
Chunrong Gong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583886

11,272 views
13 citations

Review

Published on 04 Apr 2025

The role of immune checkpoints PD-1 and CTLA-4 in cardiovascular complications leading to heart failure

in Inflammation

Shoulian Huang
Yu Kang
Ting Liu
Yan Xiong
Zixuan Yang
Qing Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561968

5,761 views
13 citations

Review

Published on 03 Apr 2025

The dual role of IL-17 in periodontitis regulating immunity and bone homeostasis

in Inflammation

Zhongyuan Tang
Lijian Jin
Yanqi Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578635

4,645 views
12 citations

Review

Published on 03 Apr 2025

Fibroblast heterogeneity and its role in generating protective immunity in the secondary lymphoid organs

in Inflammation

Hadida Yasmin
Remya P. G. Ramesh
Ann Mary Joseph
Uday Kishore

Frontiers in Immunology

doi 10.3389/fimmu.2025.1519789

3,465 views
3 citations

Editorial

Published on 03 Apr 2025

Editorial: Crosstalk in ferroptosis, immunity & inflammation

in Inflammation

Yu’e Liu
Guangzhen Wu
Linjing Feng
Qi Feng
Hua Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587075

2,421 views
1 citation

Original Research

Published on 02 Apr 2025

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

in Inflammation

Man Zhao
Zexin Yang
Yan Kang
Zhenya Fang
Changqing Zhang
Chunying Wang
Meijuan Zhou
Junjun Guo
Anna Li
Meihua Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530015

4,445 views

Brief Research Report

Published on 02 Apr 2025

Angiotensinogen and C3 compete for renin-induced complement activation

in Inflammation

Ann-Charlotte Kristoffersson
Albin Sköld
Charlotte Welinder
Markus Wendler
Gabriella Kalliokoski
Zivile Bekassy
Diana Karpman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563868

2,457 views
3 citations

Original Research

Published on 01 Apr 2025

PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution

in Inflammation

Lin Zhang
Jiaqi Tian
Yongfei Zheng
Shuyin Duan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561290

2,936 views
1 citation

Review

Published on 01 Apr 2025

Pyroptosis for osteoarthritis treatment: insights into cellular and molecular interactions inflammatory

in Inflammation

Minghui Lin
Cunxin Zhang
Haiming Li
Kang Li
Shuao Gou
Xiao He
Chaoliang Lv
Kai Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556990

9,048 views
12 citations

Original Research

Published on 01 Apr 2025

Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis

in Inflammation

Alessia Provera
Naresh Naik Ramavath
Laila Lavanya Gadipudi
Cristina Vecchio
Marina Caputo
Alessandro Antonioli
Sabrina Tini
Anteneh Nigussie Sheferaw
Simone Reano
Nicoletta Filigheddu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1518687

7,914 views
2 citations

Original Research

Published on 31 Mar 2025

CD121b-positive neutrophils predict immunosuppression in septic shock

in Inflammation

Jian Chen
Jinghe Zhang
Siao Chen
Jingkun Qin
Xinyu Hu
Shengdi Xi
Lin Zhang
Min Zhou
Yonggang Zhou
Binqing Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565797

4,533 views

Original Research

Published on 31 Mar 2025

Keloids and inflammation: the crucial role of IL-33 in epidermal changes

in Inflammation

ZongAn Chen
YaTing Yang
XiuXia Wang
LingLing Xia
WenBo Wang
XiaoLi Wu
Zhen Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1514618

4,149 views
3 citations

5,809 articles

articles

Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model

Establishment of fracture blister model and analysis of plasma protein markers in rats

Targeting the immuno-inflammatory-microbial network: a key strategy for sepsis treatment

MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro

The role of ubiquitination and deubiquitination in the pathogenesis of non-alcoholic fatty liver disease

Acute myeloid leukemia-derived extracellular vesicles induced DNA methylation changes responsible for inflammatory program in normal hematopoietic stem progenitor cells

Advances in cell therapy for orthopedic diseases: bridging immune modulation and regeneration

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

Ferroptosis-related protein biomarkers for diagnosis, differential diagnosis, and short-term mortality in patients with sepsis in the intensive care unit

Understanding chronic inflammation: couplings between cytokines, ROS, NO, Cai2+, HIF-1α, Nrf2 and autophagy

Spinal neuron-glial crosstalk and ion channel dysregulation in diabetic neuropathic pain

Macrophage caspase-8 inhibition accelerates necrotic core expansion in atheroma plaque in mice

NLRP3 inflammasome in Alzheimer’s disease: molecular mechanisms and emerging therapies

The role of immune checkpoints PD-1 and CTLA-4 in cardiovascular complications leading to heart failure

The dual role of IL-17 in periodontitis regulating immunity and bone homeostasis

Fibroblast heterogeneity and its role in generating protective immunity in the secondary lymphoid organs

Editorial: Crosstalk in ferroptosis, immunity & inflammation

BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome

Angiotensinogen and C3 compete for renin-induced complement activation

PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution

Pyroptosis for osteoarthritis treatment: insights into cellular and molecular interactions inflammatory

Vegetal oil-based ketogenic diet improves inflammation and fibrosis in experimental metabolic dysfunction-associated steatohepatitis

CD121b-positive neutrophils predict immunosuppression in septic shock

Keloids and inflammation: the crucial role of IL-33 in epidermal changes