Frontiers in Immunology | Molecular Innate Immunity

Original Research

Accepted on 01 Aug 2025

Glycoproteomics analysis of Complement Factor H and its effect on complement regulatory function during Streptococcus pneumoniaeassociated hemolytic uremic syndrome

in Molecular Innate Immunity

Laura M. Baas
Kioa L. Wijnsma
Fokje Zijlstra
Nicole C.A.J. van de Kar
Lieke Ter Steeg
Antonia H.M. Bouts
Marloes A.H.M. Michels
Jeroen D. Langereis
Dirk Lefeber
Hans J.C.T. Wessels

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645196

Original Research

Published on 01 Aug 2025

PLCγ2 controls neutrophil-like cell sensitivity through calcium oscillation and gates chemoattractant concentration range for chemotaxis

in Molecular Innate Immunity

Xuehua Xu
Woo Sung Kim
Arthur Lee
Tian Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633390

226 views

Editorial

Accepted on 31 Jul 2025

Editorial: Roles of Granzymes in Inflammation, Aging, and Autoimmunity

in Molecular Innate Immunity

Fehim Esen
Christopher T Turner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672898

Original Research

Published on 31 Jul 2025

Long-term hyperglycaemia exerts contrasting effects on M1- and M2-like macrophages

in Molecular Innate Immunity

Sona Margaryan
David Poghosyan
Susanna Ghonyan
Lina Hakobyan
Anush Martirosyan
Gayane Manukyan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639650

325 views

Original Research

Accepted on 30 Jul 2025

MiRNA sequencing of platelet and exosome revealed platelet miR-199b-3p as a potential biomarker in lung adenocarcinoma

in Molecular Innate Immunity

Xiaoxia Wen
SIsi Yu
Ping Leng
Yu Liu
Huaichao Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619448

133 views

Original Research

Published on 30 Jul 2025

Transcriptional responses in different mouse models of septic liver injury differ from those in patients with septic liver injury

in Molecular Innate Immunity

Qin Yan
Wei Fan
Xinsen He
Shi Zheng
Xiaolin Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556392

273 views

Original Research

Accepted on 29 Jul 2025

Prioritizing FDA approved therapeutics for treating sepsis phenotypes: A network modeling approach based on neutrophil proteomics

in Molecular Innate Immunity

Jordan Langston
Dan Liu
Qingliang Yang
Salim Merali
Carmen Merali
Narender Singh
Jennifer FIsher
Balabhaskar Prabhakarpandian
Laurie Kilpatrick
Mohammad F Kiani

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646141

Original Research

Published on 29 Jul 2025

RORα-activated mitophagy attenuating hypoxic-ischemic encephalopathy via suppression of microglial cGAS-STING axis

in Molecular Innate Immunity

Lei Song
Haiyan Shen
Fei Hong
Weiyan Zhang
Hongyi Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592737

285 views

Mini Review

Accepted on 28 Jul 2025

Dual Roles of Innate Immune Cells and Cytokines in Shaping the Breast Cancer Microenvironment

in Molecular Innate Immunity

Chen Zhang
Wei Liu
Ping Yang
Rubing Lin
Lulan Pu
Hongying Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654947

198 views

Brief Research Report

Accepted on 28 Jul 2025

Elevated C-reactive Protein and D-dimer to predict Venous Thromboembolism in Patients with Bladder Cancer

in Molecular Innate Immunity

Bo Chen
Tonghe Zhang
Yisong Wang
Zhaoyang Li
Haoyu Liu
Zhan Jiang
Huitang Yang
Yandong Cai
Guoju Fan
Kaiqiang Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652139

186 views

Mini Review

Accepted on 28 Jul 2025

Evolving insights on the role of microglia in neuroinflammation, plasticity, and regeneration of the injured spinal cord

in Molecular Innate Immunity

Emily A Swarts
Faith H Brennan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621789

Original Research

Accepted on 28 Jul 2025

The Role of ZC3H13 in Promoting M2 Macrophage Infiltration via m6A Methylation in Esophageal Squamous Cell Carcinoma Tumor Progression

in Molecular Innate Immunity

Qihang Yan
Chendi Xu
Li Gong
Dachuan Liang
Jie Yang
Yuzhen Zheng
Junye Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612041

Review

Published on 28 Jul 2025

The Role of SR-BI in sepsis: leveraging mechanistic insights to advance precision steroid therapy

in Molecular Innate Immunity

Ling Guo
Qian Wang
Xiang-An Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643395

376 views

Original Research

Published on 28 Jul 2025

Conserved function of bat TBK1 in activating innate immunity against RNA viruses: insights into the innate immune response in bats

in Molecular Innate Immunity

Qiuju Liu
Qi Shao
Caixia Xu
Chao Liu
Shuhan Li
Jie Wang
Xia Liu
Kehui Zhang
Yaxian Yan
Jianhe Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574866

443 views

Review

Published on 28 Jul 2025

Neutrophil extracellular traps and interleukin-1β in cystic fibrosis lung disease

in Molecular Innate Immunity

Kayla M. Fantone
Naveen Gokanapudi
Balázs Rada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595994

376 views

Review

Published on 28 Jul 2025

Interactions between islet-resident macrophages and β cells in diabetes

in Molecular Innate Immunity

Danhuai Zhang
Lingzhe Meng
Minghui Xi
Shuai Li
Wantong Chen
LuYi Li
Lingling Dong
Na Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630507

435 views