Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 02 May 2025

Analysis of humoral and cellular immune activation up to 21 months after heterologous and homologous COVID-19 vaccination

in Vaccines and Molecular Therapeutics

Davide Torre
Chiara Orlandi
Ilaria Conti
Simone Barocci
Eugenio Carlotti
Mauro Magnani
Anna Casabianca
Giuseppe Stefanetti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579163

373 views

Original Research

Accepted on 30 Apr 2025

Prime-boost vaccination with chimeric antigens adjuvanted in Montanide TM ISA50 V2 confers protection against experimental Lepeophtheirus salmonis infestation in Atlantic salmon (Salmo salar L.)

in Vaccines and Molecular Therapeutics

Alianet Rodríguez
Koestan Gadan
Lincidio Perez Sanchez
Oystein Evensen
Mario Pablo Estrada Garcia
Yamila Carpio

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570948

Original Research

Published on 30 Apr 2025

Transcriptomic analysis after SARS-CoV-2 mRNA vaccination reveals a specific gene signature in low-responder hemodialysis patients

in Vaccines and Molecular Therapeutics

Simone Lucchesi
Giorgio Montesi
Jacopo Polvere
Fabio Fiorino
Gabiria Pastore
Margherita Sambo
Marialetizia Lusini
Francesca Montagnani
Annalisa Ciabattini
Francesco Santoro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1508659

499 views

Correction

Published on 30 Apr 2025

Corrigendum: Enhancing cell-mediated immunity through dendritic cell activation: the role of Tri-GalNAc-modified PLGA-PEG nanoparticles encapsulating SR717

in Vaccines and Molecular Therapeutics

Yang Gong
Hongbin Jia
Wenrui Dang
Ting Zhou
Pu He
Xiaolei Wang
Bingdong Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590490

218 views

Study Protocol

Accepted on 29 Apr 2025

Development of an intranasal, universal influenza vaccine in an EUfunded public-private partnership: the FLUniversal consortium

in Vaccines and Molecular Therapeutics

Victor Cnossen
Paula Leao Moreira
Othmar Engelhardt
Jerzy Samolej
Geert Groeneveld
Simon Jochems
Wesley Huisman
Gabriel Pedersen
Katharina Wørzner
Lukas Recek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568778

100 views

Original Research

Published on 29 Apr 2025

A bivalent self-amplifying RNA vaccine against yellow fever and Zika viruses

in Vaccines and Molecular Therapeutics

Peter Battisti
Matthew R. Ykema
Darshan N. Kasal
Madeleine F. Jennewein
Samuel Beaver
Abbie E. Weight
Derek Hanson
Jasneet Singh
Julie Bakken
Noah Cross

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569454

395 views

Original Research

Accepted on 28 Apr 2025

Humoral and cellular immune responses in cattle upon Clostridium chauvoei vaccination and challenge

in Vaccines and Molecular Therapeutics

Andrea Rossi
Julio Guarnaschelli
Analía Rial
María Moreno
Mariana Rivera-Patron
Andres Iriarte
Jose Alejandro Chabalgoity

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584168

163 views

Original Research

Accepted on 28 Apr 2025

A Novel and Safe SmartCap® SC101 to Develop COVID-19 mRNA Vaccine STP2104 Inducing Potent Immune Responses in Humans

in Vaccines and Molecular Therapeutics

Rachel Kim
Tae-Gi Uhm
Jisu Kim
Dayeon Woo
Uk-Il Kim
Xue Meng
Byounggu Yang
Jonghyeon Kim
Sunkyung Yoon
Joo-Young Lee

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571092

412 views

Review

Accepted on 28 Apr 2025

Peptide Vaccines: An Innovative Therapeutic Approach against Antibiotic-Resistant Bacterial Infections

in Vaccines and Molecular Therapeutics

Fatemeh Tavassoli Razavi
Nasrin Salari
Atena Emami
Dariush Haghmorad
Rasoul Baharlou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567584

Systematic Review

Accepted on 28 Apr 2025

Immune mechanisms mediating the heterologous effects of BCG vaccination: a systematic review

in Vaccines and Molecular Therapeutics

Louis Torracinta
Nino Gogichadze
Rachel Tanner

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567111

108 views

Correction

Published on 28 Apr 2025

Corrigendum: Adeno-associated virus as an effective malaria booster vaccine following adenovirus priming

in Vaccines and Molecular Therapeutics

Yenni Yusuf
Tatsuya Yoshii
Mitsuhiro Iyori
Kunitaka Yoshida
Hiroaki Mizukami
Shinya Fukumoto
Daisuke S. Yamamoto
Asrar Alam
Talha Bin Emran
Fitri Amelia

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592118

306 views

Brief Research Report

Accepted on 25 Apr 2025

Expression of salivary hepcidin and its inducer, interleukin 6 as well as and type I Interferons are significantly elevatedhigh in infants with poor oral rotavirus vaccine take in South Africa

in Vaccines and Molecular Therapeutics

Vusumuzi Mabasa
Mapeseka L Seheri
Cliff Abdul Magwira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1517893

111 views

Review

Accepted on 25 Apr 2025

Progress on the Combination Vaccines and Co-administration of Influenza Virus and SARS-CoV-2 Vaccines

in Vaccines and Molecular Therapeutics

Chengyu Hu
Chenguang Niu
Ke He
Mengyu Li
Xiaonan Gao
Qiannan Wei
Weiyang Sun
Yongkun Zhao
Yuanguo Li
Yuwei Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578733

269 views

Original Research

Accepted on 25 Apr 2025

Addressing SARS-CoV-2 Evolution: Neutralization of Emerging Variants of Concern by the AVX/COVID-12 'Patria' Vaccine Based on HexaPro-S Ancestral Wuhan Spike or Its Updated BA.2.75.2 Version

in Vaccines and Molecular Therapeutics

Gregorio Carballo-Uicab
Gabriela Mellado-Sanchez
Edith González-González
Juana Salinas-Trujano
Ivette Mendoza-Salazar
Karina López-Olvera
Keyla María Gómez-Castellano
Ma. Isabel Salazar
Jesus Miguel Torres Flores
Héctor Elías Chagoya-Cortés

Frontiers in Immunology

doi 10.3389/fimmu.2025.1565934

366 views

Original Research

Published on 25 Apr 2025

Heterologous prime–boost Zika virus vaccination induces comprehensive humoral and cellular immunity in mouse models

in Vaccines and Molecular Therapeutics

Giuditta De Lorenzo
Rapeepat Tandavanitj
Lorena Preciado-Llanes
Ricardo Sanchez-Velazquez
Raissa Prado Rocha
Young Chan Kim
Arturo Reyes-Sandoval
Arvind H. Patel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578427

470 views

Review

Accepted on 24 Apr 2025

Applying computational protein design to therapeutic antibody discovery - current state and perspectives

in Vaccines and Molecular Therapeutics

Weronika Bielska
Igor Jaszczyszyn
Paweł Dudzic
Bartosz Janusz
Dawid Chomicz
Sonia Wrobel
Victor Greiff
Ryan Feehan
Jared Adolf-Bryfogle
Konrad Krawczyk

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571371