Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 05 Jun 2025

Construction and evaluation of a Salmonella minicell-based dendritic cell-targeted multi-epitope vaccine against Helicobacter pylori

in Vaccines and Molecular Therapeutics

Jiaxue Yang
Kehan Chen
Yalan Zhu
Tiancheng Xie
Chubin Fang
Chuan Wang
Tian Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595096

734 views

Original Research

Published on 05 Jun 2025

The fusion subunit vaccine L-DBF protects aged mice against heterologous lethal Shigella challenge after prior exposure

in Vaccines and Molecular Therapeutics

Md Shafiullah Parvej
Ti Lu
Suhrid Maiti
Zackary K. Dietz
Debaki R. Howlader
Mst Nusrat Zahan
Alexa Cato
Satabdi Biswas
William D. Picking
Wendy L. Picking

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586537

709 views

Brief Research Report

Published on 04 Jun 2025

An mRNA-based workflow validating neo-epitope presentation through HLA-I/peptide affinity purification

in Vaccines and Molecular Therapeutics

Arthur Esprit
Dorien Autaers
Kris Thielemans
Elise Pepermans
Kurt Boonen
Geert Baggerman
Lorenzo Franceschini
Karine Breckpot

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566461

971 views

Original Research

Published on 04 Jun 2025

Computational design and evaluation of multiepitope vaccines against herpes simplex virus type 1

in Vaccines and Molecular Therapeutics

Zibo Zhao
Weixiong Wang
Jiaping Pang
Bei Zhou
Xin Li
Yifei Wang
Kai Zheng
Zhe Ren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581571

1,100 views

Original Research

Accepted on 03 Jun 2025

Comparative Transcriptomic Analysis of Mouse Macrophages Infected with Live Attenuated Vaccine Strains of Mycobacterium tuberculosis

in Vaccines and Molecular Therapeutics

Raja Veerapandian
Barbara Yang
Areanna Carmona
Melina Sedano
Victoria Reid
Rodrigo Jimenez
Jessica Chacon
Chinnaswamy Jagannath
Enrique Ivan Ramos
Shrikanth Gadad

Frontiers in Immunology

doi 10.3389/fimmu.2025.1583439

286 views

Review

Published on 03 Jun 2025

Immunomodulatory effects of gut microbiota on vaccine efficacy against respiratory pathogens

in Vaccines and Molecular Therapeutics

Li Xue
Chunhua Wang
Chuanyu Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618921

683 views

Brief Research Report

Accepted on 02 Jun 2025

Immune Responses Following DNA Vaccination by Needle-Free Injection Against Burkholderia pseudomallei Hemolysin Co-regulated Protein 1

in Vaccines and Molecular Therapeutics

Christopher K Cote
Michael Davies
Sergei S Biryukov
Christopher P Klimko
Jennifer Dankmeyer
Nathaniel O Rill
Melissa Hunter
Christopher T Braun
Deven W Patrick
Tyrique D David

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612540

220 views

Original Research

Accepted on 02 Jun 2025

Characterization of the clinical relevance and hypoallergenic peptides of the newly evidenced major allergen Hum j 1

in Vaccines and Molecular Therapeutics

Jin-Lyu Sun
Ya-Li Cheng
Qiong Li
YongShi Yang
Yibo Hou
Zhiqiang Xu
Ji-Fu Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1588870

187 views

Original Research

Accepted on 02 Jun 2025

Correlation between Microneutralization Test and a Multiplexed Immunoassay for evaluation of Monkeypox and Vaccinia virus antibodies before and after smallpox vaccination

in Vaccines and Molecular Therapeutics

Serena Marchi
Giulia Piccini
Ed Remarque
Giulia Roscia
Bianca Semplici
Paolo Cantaloni
Noemi Guerrini
Roberta Zannella
Rosa Coluccio
Linda Benincasa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585284

193 views

Original Research

Accepted on 02 Jun 2025

A consensus mathematical model of vaccine-induced antibody dynamics for multiple vaccine platforms and pathogens

in Vaccines and Molecular Therapeutics

Kristen Wilding
Carmen Molina-París
Jessica Kubicek-Sutherland
Benjamin McMahon
Alan S Perelson
Ruy Ribeiro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596518

162 views

Original Research

Published on 30 May 2025

Negative associations of age and lifestyle factors with the antibody response to the COVID-19 vaccine BNT162b2 in health workers from Spain

in Vaccines and Molecular Therapeutics

Luis Sarabia de Ardanaz
Esther Serrano-Conde
Ana Fuentes
Alba Leyva
Federico García
Pilar Requena

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590939

480 views

Original Research

Accepted on 29 May 2025

Influenza specific antibody-mediated and complement-dependent cellular cytotoxicity inducing antibodies in vaccinated and infected pigs

in Vaccines and Molecular Therapeutics

Renukaradhya J Gourapura
Mithilesh Singh
Gabriela Mansano Do Nascimento
Sankar Renu
Dina Bugybayeva
Comfort Olaitan Comfort
Raksha Suresh
Jennifer Schrock
Sara Dolatyabi
Diego G. Diel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600761

350 views

Review

Published on 29 May 2025

A review of the efficacy of clinical tuberculosis vaccine candidates in mouse models

in Vaccines and Molecular Therapeutics

Lidia del Pozo-Ramos
Andreas Kupz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609136

1,545 views

Original Research

Accepted on 28 May 2025

The F1F3 recombinant chimera induced higher vaccine efficacy than its independent F1 and F3 components against Leishmania (L.) infantum chagasi mice infection.

in Vaccines and Molecular Therapeutics

Daniele Crespo Gomes
Maria Paula Fonseca-Ribeiro
MARCUS VINICIUS SILVA
Clarisa B. Palatnik-de-Sousa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598755

147 views

Original Research

Published on 28 May 2025

Heterologous prime-boost vaccination drives stromal activation and adaptive immunity against SARS-CoV-2 variants

in Vaccines and Molecular Therapeutics

Ji Hyang Jeon
Seongryong Kim
Seo-Yeon Kim
Kwang-Soo Shin
Bongju Park
Soojeong Chang
Chang-Yuil Kang
You-Jin Kim
Jong-Eun Park
Sungsu Youk

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597417

965 views

Original Research

Accepted on 27 May 2025

The TNFa-binding domain of the therapeutic antibody adalimumab elicits CD4 T-cell responses in Rheumatoid Arthritis patients

in Vaccines and Molecular Therapeutics

Mateusz Makuch
Josine Van Beek
Carla A Wijbrandts
Marja Aalbers
Philippe Stas
Alexander Meijer
Anja ten Brinke
T Rispens
Paul Peter Tak
Gertjan Wolbink

Frontiers in Immunology

doi 10.3389/fimmu.2025.1549781

368 views