Frontiers in Immunology | Vaccines and Molecular Therapeutics

Original Research

Published on 16 May 2025

Development of a multi-neoepitope vaccine targeting non-small cell lung cancer through reverse vaccinology and bioinformatics approaches

in Vaccines and Molecular Therapeutics

Elahe Asadollahi
Alireza Zomorodipour
Zahra-Soheila Soheili
Babak Jahangiri
Majid Sadeghizadeh

Frontiers in Immunology

doi 10.3389/fimmu.2025.1521700

1,940 views

Brief Research Report

Published on 16 May 2025

Expression of salivary hepcidin and its inducer, interleukin 6 as well as type I interferons are significantly elevated in infants with poor oral rotavirus vaccine take in South Africa

in Vaccines and Molecular Therapeutics

Vusumuzi Mabasa
Mapeseka L. Seheri
Cliff A. Magwira

Frontiers in Immunology

doi 10.3389/fimmu.2025.1517893

1,167 views
1 citation

Original Research

Accepted on 14 May 2025

Neutralizing antibody response to Omicron subvariants BA.1 and BA.5 in children and adolescents following the two-dose CoronaVac protocol (Immunita-002, Brazil): A 12-month longitudinal study

in Vaccines and Molecular Therapeutics

Camila Corsini
Guilherme Campos
Priscila Fernanda da S Martins
Priscilla Soares Filgueiras
Ana Esther De S Lima
Sarah Vieira Contin Gomes
Caroline de AL Curimbaba
Daniela A Lorencini
Eolo M Junior
Victor M da Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589733

353 views

Review

Published on 14 May 2025

Nucleic acid vaccines: innovations, efficacy, and applications in at-risk populations

in Vaccines and Molecular Therapeutics

Emily N. Konopka
Arden O. Edgerton
Michele A. Kutzler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1584876

1,530 views

Original Research

Published on 14 May 2025

Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines

in Vaccines and Molecular Therapeutics

Cassie G. Ackerley
Srilatha Edupuganti
Chenchen Yu
Alison C. Roxby
Kelly E. Seaton
Linda-Gail Bekker
Mary Allen
Stephen C. DeRosa
Nicole L. Yates
Jack Heptinstall

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557009

1,222 views

Original Research

Accepted on 13 May 2025

Nanolipoprotein Particle (NLP) Vaccine Confers Protection Against Yersinia pestis Aerosol Challenge in a BALB/c Mouse Model

in Vaccines and Molecular Therapeutics

Christopher K Cote
Sergei S Biryukov
Amy Rasley
Michael Davies
Christopher P Klimko
Jennifer Dankmeyer
Melissa Hunter
Nathaniel O Rill
Jennifer L Shoe
Jeremy A Miller

Frontiers in Immunology

doi 10.3389/fimmu.2025.1603710

426 views

Review

Published on 13 May 2025

The recent advances in vaccine adjuvants

in Vaccines and Molecular Therapeutics

Jiayin Xing
Xiangxiang Zhao
Xiaotian Li
Ren Fang
Mingrui Sun
Yang Zhang
Ningning Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557415

2,365 views

Original Research

Published on 13 May 2025

Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120

in Vaccines and Molecular Therapeutics

Muhammad Zeeshan Ahmed
Tazeen Rao
Zeeshan Mutahir
Sarfraz Ahmed
Najeeb Ullah
Suvash Chandra Ojha

Frontiers in Immunology

doi 10.3389/fimmu.2025.1480025

1,950 views

Original Research

Published on 13 May 2025

Comprehensive immunoinformatics and bioinformatics strategies for designing a multi-epitope based vaccine targeting structural proteins of Nipah virus

in Vaccines and Molecular Therapeutics

Shivangi Sharma
Pragya D. Yadav
Sarah Cherian

Frontiers in Immunology

doi 10.3389/fimmu.2025.1535322

1,333 views

Original Research

Published on 12 May 2025

Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation

in Vaccines and Molecular Therapeutics

Dorit Fabricius
Carolin Ludwig
Matthias Proffen
Janina Hägele
Judith Scholz
Christiane Vieweg
Immanuel Rode
Simone Hoffmann
Sixten Körper
Hubert Schrezenmeier

Frontiers in Immunology

doi 10.3389/fimmu.2025.1580448

1,780 views

Review

Published on 09 May 2025

Nanotechnology-driven advances in intranasal vaccine delivery systems against infectious diseases

in Vaccines and Molecular Therapeutics

Zhihan Zhang
Yumeng Yang
Liwen Huang
Lei Yuan
Sijian Huang
Zihang Zeng
Yuan Cao
Xianghong Wei
Xiaomei Wang
Mingsong Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573037

1,241 views

Original Research

Published on 08 May 2025

Ten years after introduction of NADC30-like strain in China: a novel chimeric porcine reproductive and respiratory syndrome vaccine candidate

in Vaccines and Molecular Therapeutics

Weixin Wu
Xinyu Fang
Yiyao Jiang
Jiameng Hu
Qiongqiong Zhou
Peng Gao
Yongning Zhang
Xinna Ge
Jun Han
Xin Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585197

1,141 views

Original Research

Published on 08 May 2025

Immunological response and implications of Ad26.COV2. S (Janssen COVID-19 vaccine) vaccine in diabetic patients: a prospective cohort study in Ethiopia

in Vaccines and Molecular Therapeutics

Chala Kenenisa Edae
Abdisa Tufa Bedada
Maria Degef Teklemariam
Abera Botore Gudisa
Abdurahman Adamu
Solomon Genet Gebre

Frontiers in Immunology

doi 10.3389/fimmu.2025.1546114

1,206 views

Systematic Review

Published on 08 May 2025

Artificial intelligence in vaccine research and development: an umbrella review

in Vaccines and Molecular Therapeutics

Rabie Adel El Arab
May Alkhunaizi
Yousef N. Alhashem
Alissar Al Khatib
Munirah Bubsheet
Salwa Hassanein

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567116

5,472 views
1 citation

Original Research

Published on 05 May 2025

The MVA-VP2-NS1-2A-NS2-Nt vaccine candidate provides heterologous protection in sheep against bluetongue virus

in Vaccines and Molecular Therapeutics

Luis Jiménez-Cabello
Sergio Utrilla-Trigo
Miguel Illescas-Amo
Karen Rodríguez-Sabando
Julio Benavides-Silván
Eva Calvo-Pinilla
Javier Ortego

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566225

1,505 views

Original Research

Published on 02 May 2025

Analysis of humoral and cellular immune activation up to 21 months after heterologous and homologous COVID-19 vaccination

in Vaccines and Molecular Therapeutics

Davide Torre
Chiara Orlandi
Ilaria Conti
Simone Barocci
Eugenio Carlotti
Mauro Magnani
Anna Casabianca
Giuseppe Stefanetti

Frontiers in Immunology

doi 10.3389/fimmu.2025.1579163

1,385 views