Frontiers in Immunology | Viral Immunology

Original Research

Published on 27 Aug 2025

IFIT3 activation significantly contributes to HIV-1-associated neurodegenerative disorder-mediated neuroinflammation

in Viral Immunology

Ranjit Kumar Das
Nirakar Sahoo
Deepa Roy
Chun Xu
Jose Galarza
Maria Camila Mejia Garza
Hansapani Rodrigo
Asim K. Duttaroy
Upal Roy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532318

313 views

Mini Review

Published on 27 Aug 2025

The role of Tat in HIV latency and reactivation

in Viral Immunology

David M. Margolis
Edward P. Browne

Frontiers in Immunology

doi 10.3389/fimmu.2025.1650385

226 views

Review

Accepted on 25 Aug 2025

Host Proteases: Key Regulators in Viral Infection and Therapeutic Targeting

in Viral Immunology

Qiongrong Xia
Xiaoyan Xia
Huacui Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671173

164 views

Brief Research Report

Accepted on 25 Aug 2025

Serum Matters: Human Platelet Lysate Enables Physiological Modeling of HIV-1 Infection in Dendritic Cells

in Viral Immunology

Paul Schweighofer
Magdalena Lang
Wilfried Posch
Doris Wilflingseder

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661425

135 views

Original Research

Accepted on 25 Aug 2025

Antiviral and immunomodulatory effect of zapnometinib in animal models and hospitalized COVID-19 patients

in Viral Immunology

Yvonne Fuell
Lara Maria Schüssele
Hazem Hamza
Helen Hoffmann
Martin Bauer
Stephan Stenglein
Oliver Pötz
Andreas Steinhilber
Viktoria Anselm
Mark W Delany

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631721

181 views

Correction

Accepted on 22 Aug 2025

Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile

in Viral Immunology

Rocío Rubio
Ruth Aguilar
Mariona Bustamante
Erica Muñoz
Miquel Vazquez-Santiago
Rebeca Santano
Marta Vidal Costa
Natalia Rodrigo Melero
Daniel Parras
Pau Serra

Frontiers in Immunology

doi 10.3389/fimmu.2025.1672095

168 views

Original Research

Published on 21 Aug 2025

Attenuation of IFITM proteins’ antiviral activity through sequestration into intraluminal vesicles of late endosomes

in Viral Immunology

David Prikryl
You Zhang
Smita Verma
Gregory B. Melikyan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647166

349 views

Original Research

Published on 21 Aug 2025

Integrative scRNA-seq and transcriptomic analysis initially reveals monocyte/macrophage activation drives EV-A71-induced immune dysregulation and neural injury in severe HFMD

in Viral Immunology

Muqi Wang
Meng Zhang
Huiling Deng
Yufeng Zhang
Chenrui Liu
Yuan Chen
Chuting Zhang
Wen Zhang
Xiaoli Jia
Shuangsuo Dang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620633

353 views

Original Research

Published on 20 Aug 2025

The role of the 3′-UTR of the chemokine receptor CCR2 and hnRNPA0 in regulating mRNA stability and subcellular distribution in human CD4+ T cells

in Viral Immunology

Yunus Yukselten
Hanan Wishah
Lingyun Wang
Richard E. Sutton

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655273

655 views

Review

Accepted on 19 Aug 2025

HIV-Associated Depression: A Translational Framework Targeting Neuroimmune Inflammation and Psychosocial Stress Modulation

in Viral Immunology

Fei Yu
Yue Zhu
Yiran Fan
Mingqi Chen
Qing Peng
Shenghao Li
Liyuan Hao
Fanghang Ye
Jiajun Xia
Xiaoyu Hu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1645991

194 views

Correction

Published on 19 Aug 2025

Correction: High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza

in Viral Immunology

Frontiers Production Office

Frontiers in Immunology

doi 10.3389/fimmu.2025.1685215

268 views

Case Report

Accepted on 18 Aug 2025

Human Cytomegalovirus Infection-Induced Lymphocytosis Diagnosed by Metagenomic Next-Generation Sequencing：A Case Report And Literature Review

in Viral Immunology

Shaofan Zhang
Li Sun
Liman Wang
Yuwei Liu
Gao Tan
Tao Liu
Wen Yang
Xiaoli Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1637085

119 views

Original Research

Published on 18 Aug 2025

Immune counter-evolution: immortalized B cell clones can undergo ex vivo directed evolution to counteract viral escape

in Viral Immunology

Casper Marsman
Jurgen Heinen
Vanessa Clerico Mosina
Kelly Maijoor
Arjen Q. Bakker
Michael Koslowski
Alessandra Villa
Stefano Gullà

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648717

705 views

Original Research

Accepted on 15 Aug 2025

c-Met Inhibitor NVP-BVU972 Induces Antiviral Protection and Suppresses NF-κB-Mediated Inflammation

in Viral Immunology

Yang Zhao
Yunfei Xie
Xingyu Chen
Hongli Jia
Xiao Wang
Tianyi Liu
Haocheng Wang
Yang li
Xuefei Guo
fuping you

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651730

259 views

Original Research

Published on 15 Aug 2025

Ouabain alleviates Mycobacterium abscessus-triggered inflammatory responses through dual regulation of NLRP3 inflammasome activity and M1 macrophage polarization

in Viral Immunology

Nan Li
Songqiang Huang
Xing Shi
Kuo Lu
Xiu Yu
Chen Qiu
Rongchang Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1633882

789 views

Original Research

Published on 15 Aug 2025

A fusion ORF3a-E subgenomic RNA involved in SARS-CoV-2 infection efficacy by influencing cellular protein synthesis

in Viral Immunology

Yifan Zhang
Jing Li
Xinglong Zhang
Xin Zhang
Jiali Li
Heng Li
Xin Zhao
Zihan Zhang
Yingyan Li
Keqi Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619538

624 views