Frontiers in Medicine | Gene and Cell Therapy

Mini Review

Published on 06 Aug 2025

Clinical trials of nanoparticle-enhanced CAR-T and NK cell therapies in oncology: overcoming translational and clinical challenges - a mini review

in Gene and Cell Therapy

Xiaoqian Zhao
Jian Xiong
Danyang Li
Ying Zhang

Frontiers in Medicine

doi 10.3389/fmed.2025.1655693

682 views

Review

Accepted on 31 Jul 2025

Categories, applications, and potential of stem cells in bone regeneration: an overview

in Gene and Cell Therapy

Mingyang Jiao
Ting Shuai
Zhongfang Zhao
Yuwei Wu
Linwei Yu
Jingwen Sun
Raffaele De Caro
Veronica Macchi
Andrea Porzionato
Elena Stocco

Frontiers in Medicine

doi 10.3389/fmed.2025.1606100

140 views

Original Research

Accepted on 29 Jul 2025

Malignant epithelia cells-derived spermine induces APOE+ macrophages to suppress tumor immunity in adenocarcinoma of the esophagogastric junction

in Gene and Cell Therapy

Yan Zhang
Zhaoyang Liu
Huihui Sun
Zhenxiang Wang
Ye Chen
Zhiqian Hu
XINxing Li
Kai Xu
Ying Chen
Yanping Xu

Frontiers in Medicine

doi 10.3389/fmed.2025.1636699

129 views

Review

Accepted on 14 Jul 2025

Nanotechnology and Natural Killer Cell Immunotherapy: Synergistic Approaches for Precise Immune System Adjustment and Targeted Cancer Treatment in Gastrointestinal Tumors

in Gene and Cell Therapy

Xiwen Kang
Danyang Li
Rui Sun

Frontiers in Medicine

doi 10.3389/fmed.2025.1647737

217 views

Mini Review

Published on 02 Jul 2025

Toxicities associated with lymphoma-targeting bispecific antibodies—a review

in Gene and Cell Therapy

Christopher Doig
Costas Kleanthes Yannakou

Frontiers in Medicine

doi 10.3389/fmed.2025.1582975

1,974 views

Mini Review

Published on 25 Jun 2025

Cell therapy in pediatric blood diseases

in Gene and Cell Therapy

Rubí Romo-Rodríguez
Rosana Pelayo
Dalia Ramírez-Ramírez

Frontiers in Medicine

doi 10.3389/fmed.2025.1591287

1,816 views

Original Research

Published on 25 Jun 2025

Trends and emerging frontiers of mesenchymal stem cells in intervertebral disc degeneration: a bibliometric analysis (2000–2024)

in Gene and Cell Therapy

Jian Zhao
Shuwen Li
Jie Cheng
Xiang Xu
Ming Bai
Yingnan Yu
Meixia Liu
Heping Yin
Yimin Wu

Frontiers in Medicine

doi 10.3389/fmed.2025.1601806

1,253 views

Case Report

Published on 24 Jun 2025

Real-world outcomes of spinal muscular atrophy treatment with onasemnogene abeparvovec in Croatia: a comprehensive case series and literature review

in Gene and Cell Therapy

Ivan Lehman
Matija Matošević
Lovro Lamot
Branka Bunoza

Frontiers in Medicine

doi 10.3389/fmed.2025.1609072

1,778 views

Review

Published on 17 Jun 2025

Precision scalpels for the epigenome: next-gen editing tools in targeted therapies

in Gene and Cell Therapy

Ruiming Zhang
Tianqi Yao
Meiyin Fan
Xiaoying Jiang
Keshan Wang
Min Cui
Kaijian Bing
Xiaotian Xia

Frontiers in Medicine

doi 10.3389/fmed.2025.1613722

3,459 views

Original Research

Published on 11 Jun 2025

Identifying key genes associated with recurrence in non-small cell lung cancer through TCGA and single-cell analysis

in Gene and Cell Therapy

Weiyuan Li
Duo Han
Chunxiao Cao
Yuning Xie
Jingxia Shen

Frontiers in Medicine

doi 10.3389/fmed.2025.1549969

1,546 views

Review

Published on 14 May 2025

Drug-tolerant persister cells in acute myeloid leukemia: pressing challenge and promising new strategies for treatment

in Gene and Cell Therapy

Meng Li
Xiaoli Wang
Wenjuan He
Hao Zhou

Frontiers in Medicine

doi 10.3389/fmed.2025.1586552

1,985 views

Original Research

Published on 09 May 2025

Therapeutic effect of hUC-MSCs from different transplantation routes on acute liver failure in rats

in Gene and Cell Therapy

Yonghong Wang
Bei Wu
Yachao Tao
Menglan Wang
Dongbo Wu
Enqiang Chen
Hong Tang

Frontiers in Medicine

doi 10.3389/fmed.2025.1525719

1,025 views

Review

Published on 07 May 2025

The multifaceted functions of SPC25 in cancer: from molecular pathways to targeted therapy

in Gene and Cell Therapy

Yigang Jin
Minjie Chen
Fei Chen
Zhaofeng Gao
Xiaoping Li
Lingyu Hu
Dandan Cai
Siqi Zhao
Zhengwei Song

Frontiers in Medicine

doi 10.3389/fmed.2025.1550901

1,071 views

Original Research

Published on 17 Apr 2025

Integrative genomic analysis and diagnostic modeling of osteoporosis: unraveling the interplay of autophagy, osteogenesis, adipogenesis, and immune infiltration

in Gene and Cell Therapy

Lin-Jing Han
Jian-Zong Zhu
Hong-Cai Liu
Xiao-Sheng Lin
Shu-Zhong Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1544390

1,866 views

Original Research

Published on 09 Apr 2025

m6A-related genes of peripheral white blood cell in spinal cord injury as potential targets for prognosis and treatment

in Gene and Cell Therapy

Mingran Luo
Qian Wang
Jian Chen
Guoyong Yin

Frontiers in Medicine

doi 10.3389/fmed.2025.1544719

1,219 views

Original Research

Published on 04 Apr 2025

Distinct infectivity and neutralization antibody responses in the highly homologous AAV Go.1 and AAV5

in Gene and Cell Therapy

Mei Li
Haixiao Ma
Yang Wu
Yunling Gao
Jie Wang
Hanbing Wang

Frontiers in Medicine

doi 10.3389/fmed.2025.1554449

1,883 views