Frontiers in Microbiology | Microbial Physiology and Metabolism

Original Research

Published on 19 Dec 2025

norCBD disruption affects the H2-type six secretion system and multiple virulence factors in Pseudomonas aeruginosa

in Microbial Physiology and Metabolism

Md Mahamudul Haque
Sara Badr
Kangmin Duan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1717417

173 views

Original Research

Published on 18 Dec 2025

Improvement and tolerance mechanisms of Priestia megaterium to salt ions

in Microbial Physiology and Metabolism

Chunlong Wang
Shaohua Chu
Dan Zhang
Pei Zhou
Yimin You

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1730703

437 views

Original Research

Published on 17 Dec 2025

Genome organization, virulence genes, and temperature-dependent motility of an emerging pathogen, Escherichia marmotae

in Microbial Physiology and Metabolism

Pelumi M. Oladipo
Ali M. Jomaa
Jeffrey H. Withey
Jeffrey L. Ram

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1729604

646 views

Original Research

Published on 16 Dec 2025

Expression of hemerythrin-like genes from the obligate aerobe Myxococcus xanthus improves the growth of the industrially relevant Gluconobacter oxydans

in Microbial Physiology and Metabolism

Alexa L. Fleegal
Mason J. Stenzel
Paul Schweiger
Daniel J. Bretl

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1734440

558 views

Review

Accepted on 15 Dec 2025

Biofilm-Mediated Immune Dysregulation in Chronic Pulmonary Diseases: Mechanisms and Clinical Implications

in Microbial Physiology and Metabolism

Xiao Yu
Yidan Zhang
Yiwen Yao
William C Cho
Anquan Shang

Frontiers in Microbiology

Original Research

Published on 11 Dec 2025

The poly (A) polymerase pcnB modulates virulence and resistance in Klebsiella pneumoniae by differentially regulating chromosomal mRNA stability and plasmid copy number

in Microbial Physiology and Metabolism

Liaoqin Zhang
Shujie Zhang
Jun Wang
Zhongdong Zhang
Yong Xu
Chen Zhang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1709161

558 views

Original Research

Published on 09 Dec 2025

The in vitro stimulatory activity of CwlM∼P on mycobacterial MurA depends on a charged predicted interface that is distal from the CwlM phosphorylation site

in Microbial Physiology and Metabolism

Augusto Cesar Hunt-Serracin
Karen E. Tembiwa
Arinze Awagu
Soroush Ghaffari
Katie N. Kang
Cara C. Boutte

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1543775

796 views

Original Research

Accepted on 05 Dec 2025

Evaluation of tomato based agro-industrial byproducts as substrates for Trichoderma harzianum cultivation and bioinoculant potential

in Microbial Physiology and Metabolism

Antonia Esposito
Valeria Scala
Nikolay Vassilev
Maria Aragona
Loredana Canfora
Alessandro Polito
Riccardo Fiorani
Stefano Mocali

Frontiers in Microbiology

400 views

Original Research

Published on 05 Dec 2025

The metabolite ILA of Akkermansia muciniphila improves AP-related intestinal injury by targeting and inhibiting CASP3 activity

in Microbial Physiology and Metabolism

Peiyu Li
Jiuliang Yu
Tao Li
Xiaoyong Gong
Le Li
Yi Cui
Jiayi He
Bo Li
Shuqi Wu
Qingyang Guan

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1669383

1,024 views

Original Research

Published on 03 Dec 2025

Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12

in Microbial Physiology and Metabolism

Sergey V. Molev
Agnessa A. Stepanova
Tatiana V. Vybornaya
Andrey A. Khozov
Makar M. Surkov
Gennadii A. Badun
Maria G. Chernysheva
Alexander I. Netrusov
Alexander S. Yanenko
Sergey P. Sineoky

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1727951

670 views

Review

Accepted on 26 Nov 2025

Harnessing Secondary Metabolites of Endophytic Microbes: A Next-Generation Biopesticide for Crop Disease Management

in Microbial Physiology and Metabolism

Gulafasha Parveen
Waquar Akhter Ansari
Navin Kumar
Dr. Durgesh K Jaiswal

Frontiers in Microbiology

222 views

Original Research

Published on 26 Nov 2025

Temperature changes are signaled in cyanobacteria through the PipX interaction network

in Microbial Physiology and Metabolism

Antonio Llop
Sirine Bibak
Trinidad Mata-Balaguer
Lorena Tremiño
Laura Fuertes-García
José L. Neira
Ray Dixon
Asunción Contreras

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1688974

761 views

Original Research

Published on 25 Nov 2025

Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum

in Microbial Physiology and Metabolism

Fuxing Lin
Yang Jiao
Hua Jiang
Yu Zheng
Shiqin Wu
Li Zhou
Xiangmei Ren
Zhaoxin Lu
Yuanhong Li

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1698200

1,666 views

Original Research

Published on 24 Nov 2025

Metabolic reprogramming in PGPR reveals cross-feeding-driven physiological shifts and metabolic adaptations

in Microbial Physiology and Metabolism

Kamogelo Mmotla
Farhahna Allie
Thendo Mafuna
Manamele D. Mashabela
Msizi I. Mhlongo

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1668025

1,039 views

Original Research

Accepted on 21 Nov 2025

Genome-wide Characterization of Histone Deacetylases in Fusarium proliferatum: Phylogeny, Structure, and Stress Responses

in Microbial Physiology and Metabolism

Hong-Mei Shi
Hong-Xin Liao
Jin-Rui Wen
Huan-Qi Cun
Yun-Ju Hong
Zhang-Feng Hu
Furong Xu
Sulukkana Noiprasert
Kanyaphat Apiwongsrichai
Xiaoyun Liu

Frontiers in Microbiology

257 views

Editorial

Published on 21 Nov 2025

Editorial: Structure and mechanism of microbial membrane active transporters

in Microbial Physiology and Metabolism

Xiaoxu Jiang
Chuck R. Smallwood
Phillip E. Klebba
Maria Carmela Bonaccorsi di Patti

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1741179

1,007 views

Original Research

Accepted on 18 Nov 2025

Pseudomonas aeruginosa LasI/RhlI quorum sensing system controls protease-mediated autoaggregation behavior, cell envelope characteristics and extracellular proteome responses

in Microbial Physiology and Metabolism

Albin Eriksson
Maria V. Turkina
Maria Ntzouni
Karl-Eric Magnusson
Elena Vikström

Frontiers in Microbiology

207 views

Review

Published on 13 Nov 2025

Hyperoxia as a driver of gut dysbiosis

in Microbial Physiology and Metabolism

Hang Wu
Wenxia Zeng
Ninan Dai
Juan Gu
Ying He
Han Qin
Long Lin
Xiaoyun Fu
Bao Fu
Zhouxiong Xing

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1675652

1,535 views

Original Research

Published on 12 Nov 2025

Lactobacillus reuteri-derived HDCA suppresses PEDV replication while alleviating virus-triggered inflammation in piglets

in Microbial Physiology and Metabolism

Zhibiao Bian
Qianqian Li
Hongchao Gou
Yan Li
Zhiyong Jiang
Pinpin Chu
Shaolun Zhai
Huahua Kang
Chunling Li
Guanghui Zhao

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1669658

1,414 views

Original Research

Accepted on 11 Nov 2025

Magnesium modulates the stress response of oral streptococci to environmental and antibiotic challenges by altering cell envelope and nutrient transport pathways

in Microbial Physiology and Metabolism

Surabhi Mishra

Frontiers in Microbiology

265 views

Original Research

Published on 07 Nov 2025

Requirement of ClpX for CtsR dissociation from its operator elements upon heat stress in Bacillus subtilis

in Microbial Physiology and Metabolism

Marco Harms
Chelsea Kaden
Larissa M. Busch
Vishnu M. Dhople
Ulf Gerth
Manuela Gesell Salazar
Stephan Michalik
Zhanetta Zhatarova
Uwe Völker
Alexander Reder

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1699655

1,574 views

Original Research

Published on 07 Nov 2025

Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in Inonotus glomeratus

in Microbial Physiology and Metabolism

Chengbo Peng
Meng Meng
Xiaolong Yuan
Jiaojun Yu
Boyi Wang
Li Zhong
Yi Wang
Lu Li
Tingwen He
Yuan Zheng

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1658730

1,624 views

Original Research

Published on 31 Oct 2025

Screening of microbial consortium with high efficiency of lignin-degrading and its synergistic metabolic mechanism

in Microbial Physiology and Metabolism

Jinchuang Ru
Zhiyang Jiang
Jiayu Li
Xiang Li
Zhencheng Su
Tong Li
Mingkai Xu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1709019

1,708 views

Original Research

Published on 31 Oct 2025

A two-component system MechNtrB/MechNtrC related to nitrogen metabolism regulation in Micromonospora echinospora DSM43816

in Microbial Physiology and Metabolism

Yuxin Long
Jiayi Lu
Siyi Leng
Congsi Li
Haiyan Ni
Long Zou
Zhiming Wu
Zhong-er Long

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1678324

1,068 views

2,803 articles

articles

norCBD disruption affects the H2-type six secretion system and multiple virulence factors in Pseudomonas aeruginosa

Improvement and tolerance mechanisms of Priestia megaterium to salt ions

Genome organization, virulence genes, and temperature-dependent motility of an emerging pathogen, Escherichia marmotae

Expression of hemerythrin-like genes from the obligate aerobe Myxococcus xanthus improves the growth of the industrially relevant Gluconobacter oxydans

Biofilm-Mediated Immune Dysregulation in Chronic Pulmonary Diseases: Mechanisms and Clinical Implications

The poly (A) polymerase pcnB modulates virulence and resistance in Klebsiella pneumoniae by differentially regulating chromosomal mRNA stability and plasmid copy number

The in vitro stimulatory activity of CwlM∼P on mycobacterial MurA depends on a charged predicted interface that is distal from the CwlM phosphorylation site

Evaluation of tomato based agro-industrial byproducts as substrates for Trichoderma harzianum cultivation and bioinoculant potential

The metabolite ILA of Akkermansia muciniphila improves AP-related intestinal injury by targeting and inhibiting CASP3 activity

Deciphering a missing piece of the branched-chain amino acids uptake puzzle: YhjE is an L-isoleucine and L-valine transporter in Escherichia coli K-12

Harnessing Secondary Metabolites of Endophytic Microbes: A Next-Generation Biopesticide for Crop Disease Management

Temperature changes are signaled in cyanobacteria through the PipX interaction network

Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum

Metabolic reprogramming in PGPR reveals cross-feeding-driven physiological shifts and metabolic adaptations

Genome-wide Characterization of Histone Deacetylases in Fusarium proliferatum: Phylogeny, Structure, and Stress Responses

Editorial: Structure and mechanism of microbial membrane active transporters

Pseudomonas aeruginosa LasI/RhlI quorum sensing system controls protease-mediated autoaggregation behavior, cell envelope characteristics and extracellular proteome responses

Hyperoxia as a driver of gut dysbiosis

Lactobacillus reuteri-derived HDCA suppresses PEDV replication while alleviating virus-triggered inflammation in piglets

Magnesium modulates the stress response of oral streptococci to environmental and antibiotic challenges by altering cell envelope and nutrient transport pathways

Requirement of ClpX for CtsR dissociation from its operator elements upon heat stress in Bacillus subtilis

Multi-omics reveals the regulatory effects of Chinese herbal medicine substrates on secondary metabolite biosynthesis in Inonotus glomeratus

Screening of microbial consortium with high efficiency of lignin-degrading and its synergistic metabolic mechanism

A two-component system MechNtrB/MechNtrC related to nitrogen metabolism regulation in Micromonospora echinospora DSM43816