Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 20 Nov 2025

Multi-omics integration analysis based on plasma circulating proteins reveals potential therapeutic targets for ulcerative colitis

in Molecular Diagnostics and Therapeutics

Jihai Zhou
Wenwen Zhao
Yiping Lin
Bo Yang
Dongjie Sun
Zhu Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1686282

145 views

Original Research

Published on 19 Nov 2025

Progressively exploring and assessing the prognosis of bladder urothelial cancer based on the microenvironment through the integration of multiple databases

in Molecular Diagnostics and Therapeutics

Xiong Zou
Yanfeng Li
Xuefeng Peng
Changshi Gu
Qiang Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1702311

224 views

Original Research

Accepted on 18 Nov 2025

Comparative Analysis of Lipid Metabolism in Trophoblast Subpopulations in Preeclampsia and In Vitro Hypoxia Model

in Molecular Diagnostics and Therapeutics

Ivan Antipenko
Evgeny Knyazev
Timur Kulagin
Alexander Tonevitsky

Frontiers in Molecular Biosciences

Original Research

Accepted on 18 Nov 2025

Glycoprotein M6B suppresses the maintenance of glioma stem cell stemness and proliferation via the Integrin β1/β-catenin pathway

in Molecular Diagnostics and Therapeutics

Yanwen Chen
Yu Fan
Xingda Run
Maotang Liu
Shiwei Jiang
Zengli Miao
Wei Tian

Frontiers in Molecular Biosciences

Review

Accepted on 17 Nov 2025

Targeting microRNA-143 in colorectal cancer: Advances in molecular biosciences for diagnostics, therapeutic strategies, and drug resistance prediction

in Molecular Diagnostics and Therapeutics

Long Ke

Frontiers in Molecular Biosciences

135 views

Original Research

Accepted on 17 Nov 2025

Single-Cell Dissection of PTM-Related Networks Reveals an Immunosuppressed Osteosarcoma Ecosystem

in Molecular Diagnostics and Therapeutics

Jingyu Chen
Wei Zhang
Hai Yan
Jinyu Chen
Hanrui Liu
Xingyu Zhou
Haiping Zhang
Dongdong Cheng

Frontiers in Molecular Biosciences

Original Research

Published on 17 Nov 2025

A prognostic nomogram for predicting overall survival in gastric signet ring cell carcinoma patients: a SEER database and Chinese registry analysis

in Molecular Diagnostics and Therapeutics

Jie Wu
Jichen Wang
Ning Chen
Junjie Nie
Ling Xia
Quanpeng Li
Xueting Deng
Guozhong Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1704157

288 views

Editorial

Published on 17 Nov 2025

Editorial: In vitro transcription (IVT) reaction – the gateway to new therapeutic modalities

in Molecular Diagnostics and Therapeutics

Rok Sekirnik
Andreas N. Kuhn
Ana Margarida Azevedo
Zoltán Kis

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1730880

852 views

Original Research

Accepted on 14 Nov 2025

Exploring the risk stratification of carotid plaque hemodynamic based on four-dimensional blood flow technology

in Molecular Diagnostics and Therapeutics

Siyuan Zhang
Hong-liang Zhao
Xiaowei Song
Jian Wu
Rui Li

Frontiers in Molecular Biosciences

120 views

Original Research

Published on 14 Nov 2025

Investigating the molecular mechanisms of resveratrol in treating diabetic foot ulcers: a comprehensive analysis of network pharmacology and experiment validation

in Molecular Diagnostics and Therapeutics

Chao Sima
Zhe Wang
Sisi Wang
Haiyang Wang
Zhonghua Sun
Haoguo Wang
Daning Liang
Jianchi Li
Zhenning Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1708426

449 views

Original Research

Accepted on 13 Nov 2025

TRAP1 Induced Cisplatin Resistance in Gastric Cancer Cells by Regulating Oxidative Stress

in Molecular Diagnostics and Therapeutics

Zhenglei Ji
Lu Liu
Jingya Chen
Wanjing Zhu
Yunli Zhao
Huazhang Wu

Frontiers in Molecular Biosciences

Review

Published on 13 Nov 2025

Advances in 3D bioprinting for modeling the blood-brain barrier in neurodegenerative diseases

in Molecular Diagnostics and Therapeutics

Shirleen Tan
Lifeng Qiu
Jolene Wei Ling Lee
Li Zeng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1703403

483 views

Review

Accepted on 12 Nov 2025

Non-invasive exposure biomarkers of tobacco smoke exposure in smokers of classic cigarettes and users of e-cigarettes and heated tobacco products

in Molecular Diagnostics and Therapeutics

Kamila Jończyk
Aleksandra Kicman
Anna Michalska-Falkowska
Justyna Śniadach
Napoleon Waszkiewicz

Frontiers in Molecular Biosciences

105 views

Review

Accepted on 12 Nov 2025

Physiological and molecular mechanisms of tolerance to hypoxia and oxygen deficiency resistance markers

in Molecular Diagnostics and Therapeutics

Maria Silina
Dzhuliia Dzhalilova
Nikolai Fokichev
Olga Makarova

Frontiers in Molecular Biosciences

135 views

Original Research

Accepted on 11 Nov 2025

Limitations of PICADAR as a diagnostic predictive tool for primary ciliary dyskinesia

in Molecular Diagnostics and Therapeutics

Heymut Omran
Andre Schramm
Johanna Raidt
Sarah Riepenhausen
Caroline Marie Torp Nygaard
Retno Tenardi-Wenge
Tavs Qvist
Pernille Witt
Michael Storck
Heike Olbrich

Frontiers in Molecular Biosciences

125 views

Original Research

Published on 11 Nov 2025

Identification and validation of potential shared diagnostic markers for sepsis-induced ARDS and cardiomyopathy via WGCNA and machine learning

in Molecular Diagnostics and Therapeutics

Jing Wei
Baoyue Huang
Kunlin Hu
Bin Xiong
Shulin Xiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1665387

698 views