Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Accepted on 09 Sep 2025

Peripheral Circular RNAs hsa_circ_0075436 and hsa_circ_0005729 as Diagnostic and Prognostic Biomarkers in Acute Ischemic Stroke: Expression Profiles and Mechanistic Insights

in Molecular Diagnostics and Therapeutics

Wenqun Jiang
Weidong Chen
Shihao Lin
Pinpin Hou
Yichao Jin
Xiaohua Zhang
Hui Wu
Li Gao
Qin Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1657284

167 views

Original Research

Accepted on 09 Sep 2025

Clinical, phenotype and genotype correlations in primary ciliary dyskinesia suspected children in Egypt

in Molecular Diagnostics and Therapeutics

Rim Hjeij
Hoda Rizk
Mohammad Al-Haggar
Bernd Dworniczak
Dominik Otto
Heike Olbrich
Engy Osman
Heymut Omran
Tarek Eldesoky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1641739

112 views

Original Research

Published on 09 Sep 2025

Global research trends in metabolism-related intraocular malignancies: a multi-database bibliometric analysis and cross-validation study

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Zhiyong Wu
Qing Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683864

378 views

Original Research

Accepted on 08 Sep 2025

Identification of mitochondrial related gene characteristics and potential molecular mechanism of acute otitis media

in Molecular Diagnostics and Therapeutics

Dingjing Zi
Jing Hui
Leping Liang
Xiaoyong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1642269

133 views

Original Research

Accepted on 08 Sep 2025

Elucidating the multiscale mechanisms and therapeutic targets of caffeic acid in gastric cancer: A synergy of computational and experimental approaches

in Molecular Diagnostics and Therapeutics

Hongrong Zhang
Yufan Li
Ya Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1663517

204 views

Review

Accepted on 05 Sep 2025

Fibrinogen Glycosylation and Glycation: Molecular Insights into Thrombosis and Vascular Disease

in Molecular Diagnostics and Therapeutics

Serena Borghi
Francesca Nencini
Elvira Giurranna
Ilenia Barbaro
Niccolò Taddei
Claudia Fiorillo
Matteo Becatti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1680332

288 views

Original Research

Published on 03 Sep 2025

Establishment and application of a preset dilution factor strategy for human chorionic gonadotropin testing in clinical laboratory

in Molecular Diagnostics and Therapeutics

Shu Chen
Qin Li
Huaqiang Liao
Mingcai Zhao
Jie Chen
Hongyu Chen
Guangjun Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648421

724 views

Original Research

Published on 03 Sep 2025

Increased serum anti-ceramide antibodies and decreased sphingosine-1-phosphate levels in patients with obstructive sleep apnea syndrome as potential markers of endothelial dysfunction

in Molecular Diagnostics and Therapeutics

Andrzej Wiśniewski
Elżbieta Wiśniewska
Łukasz Lewandowski
Izabela Nowak
Monika Kosacka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644828

619 views

Review

Accepted on 02 Sep 2025

Transformation of acute kidney injury to chronic kidney disease: The interaction between mitophagy and NLRP3 inflammasome

in Molecular Diagnostics and Therapeutics

Yixin Zhu
Chenxi Lv
Yanheng Qiao
Hanqi Yang
Wentong Lin
Xuchen Wang
Yueqi Zhang
Bo Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643829

294 views

Original Research

Published on 02 Sep 2025

The association between composite inflammatory indicators and the clinicopathological characteristics of differentiated thyroid carcinoma

in Molecular Diagnostics and Therapeutics

Li-Yuan Yang
Li-Peng Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1660379

531 views

Correction

Published on 01 Sep 2025

Correction: Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Roberta Marongiu
Jimcy Platholi
Laibaik Park
Fangmin Yu
Garrett Sommer
Clara Woods
Teresa A. Milner
Michael J. Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1684511

544 views

Original Research

Published on 01 Sep 2025

Gut microbiota-metabolome remodeling associated with low bone mass: an integrated multi-omics study in fracture patients

in Molecular Diagnostics and Therapeutics

Xian Zhao
Bin Wu
Pengli Han
Zhongyu Wang
Renwei Cao
Shuo Chen
Cheng Cheng
Hongkai Lian
Yejun Zha
Minjuan Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1646361

657 views

Original Research

Accepted on 29 Aug 2025

Unleashing the immune modulatory potential of Leishmania amazonensis-derived extracellular vesicles in American Cutaneous Leishmaniasis

in Molecular Diagnostics and Therapeutics

Bruna Eugénia de Freitas
Maria Armanda Rodrigues
Joana Palma-Marques
Juliana Inês Weber
Ana Valério-Bolas
Rodrigo Pedro Soares
Ana Claudia Torrecilhas
Micheli Ferla
Munira Muhammad Abdel Baqui
Raul Alexander Gonzáles Córdova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593363

350 views

Correction

Accepted on 29 Aug 2025

Correction: The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

in Molecular Diagnostics and Therapeutics

Zixiang Liu
Wei Gao
Pengpeng Li
Yuanhai Zhang
Shidi Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1692389

283 views

Review

Published on 29 Aug 2025

The emerging role of exosomal LncRNAs in chronic fatigue syndrome: from intercellular communication to disease biomarkers

in Molecular Diagnostics and Therapeutics

Lei Wang
Yujia Xu
Xiang Zhong
Guiping Wang
Zijun Shi
Can Mei
Linwanyue Chen
Jianbo Zhan
Jing Cheng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1653627

2,240 views

Original Research

Published on 22 Aug 2025

The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

in Molecular Diagnostics and Therapeutics

Zixiang Liu
Pengpeng Li
Yuanhai Zhang
Shidi Zhao
Wei Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1635795

1,064 views