Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Accepted on 22 May 2025

Identification of Hub Genes in Myocardial Infarction by Bioinformatics and Machine Learning: Insights into Inflammation and Immune Regulation

in Molecular Diagnostics and Therapeutics

Juan Yang
Xiang Li
Li Ma
Jun Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1607096

Original Research

Accepted on 22 May 2025

An immune-related seven-gene signature for predicting lymph node metastasis in breast cancer

in Molecular Diagnostics and Therapeutics

Yun Hu
Lanqiao Sun
Jinhua Wang
Yuan Ji
Lili Feng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615524

Editorial

Published on 22 May 2025

Editorial: Bridging discovery and translation in novel biomarkers and big data-based biomedical studies for cancer management

in Molecular Diagnostics and Therapeutics

Lin Zhang
Weiye Qian
Qingyu Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620512

Review

Published on 22 May 2025

Insights from veterinary models for advancing oncolytic virotherapy through comparative oncology

in Molecular Diagnostics and Therapeutics

Almohanad A. Alkayyal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1615393

125 views

Review

Published on 21 May 2025

A comprehensive review of diagnostic approaches for hepatitis D

in Molecular Diagnostics and Therapeutics

Wen-Hui Liu
Jia-Yue Cui
Miao Yu
Xiao-Dong Shi
Yi-Lin Che
Chu-Yan Wang
Xiu-Mei Chi

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598784

151 views

Original Research

Accepted on 20 May 2025

Comprehensive Bioinformatics Analysis of the Common Mechanism of Atherosclerosis and Atrial Fibrillation: Emphasizing Mitochondrial Metabolic Disorder and Immune Inflammation

in Molecular Diagnostics and Therapeutics

Chen Bian
Rui Dai
Xiaotong Lei
Xiaojun Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1595048

107 views

Original Research

Published on 19 May 2025

Low‐Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients

in Molecular Diagnostics and Therapeutics

Etianne Martini Sasso
Natalie Eaton-Fitch
Peter Smith
Katsuhiko Muraki
Sonya Marshall-Gradisnik

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1582967

5,369 views

Original Research

Accepted on 16 May 2025

Mitochondrial mass and mitochondrial membrane potential of peripheral lymphocytes: promising biomarkers of systemic lupus erythematosus

in Molecular Diagnostics and Therapeutics

Guanfei Zhao
Haolong Li
Yutong Miao
Linlin Cheng
Yuying Chen
Yuan Huang
Hongyun Zhao
Yongmei Liu
Yongzhe Li
Rui Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1585847

129 views

Brief Research Report

Published on 16 May 2025

Clinical and molecular implications of cGAS/STING signaling in checkpoint inhibitor immunotherapy

in Molecular Diagnostics and Therapeutics

Hao Chen
Yang Zhong
Rongjie Feng
Xingyu Zhu
Kang Xu
Mingjie Kuang
Wei Chong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1556736

419 views

Original Research

Published on 16 May 2025

Integrating network pharmacology and experimental validation to reveal the anti-growth mechanism of panaxadiol against glioblastoma via calcium signaling

in Molecular Diagnostics and Therapeutics

Guobin Qiu
Zhiyong Wu
Dunhui Yang
Luqiu Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1598413

289 views

Original Research

Published on 15 May 2025

Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Chenxuyu Zhang
Zheng Luo
Liang Ji

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1554304

513 views

Original Research

Published on 15 May 2025

A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response

in Molecular Diagnostics and Therapeutics

Yinmeng Zhang
He Zhu
Jiawei Fan
Jiahui Zhao
Yan Xia
Nan Zhang
Hong Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599141

316 views

Editorial

Published on 15 May 2025

Editorial: Advancements and future challenges in molecular diagnostics and therapeutics

in Molecular Diagnostics and Therapeutics

Matteo Becatti
Masoud Mozafari
Roberta Risoluti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1620909

253 views

Original Research

Published on 14 May 2025

Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Roberta Marongiu
Jimcy Platholi
Laibak Park
Fangmin Yu
Garrett Sommer
Clara Woods
Teresa A. Milner
Michael J. Glass

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597130

475 views

Original Research

Published on 14 May 2025

A LODDS-based nomogram for overall and cancer-specific survival in stage III-IV gastric signet ring cell carcinoma

in Molecular Diagnostics and Therapeutics

Cenzhu Wang
Ying Fang
Yuhan Zhang
Shuhan Feng
Rui Hou
Hanfang Fan
Zeyu Wang
Lei Liu
Junli Ding
Junying Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1600626

363 views

Review

Published on 13 May 2025

Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities

in Molecular Diagnostics and Therapeutics

Ziling Pang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1578693

401 views