Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 30 Jul 2025

Inhibition of BRD4 prevents peribronchial fibrosis in mice with cutaneous lewisite exposure

in Molecular Diagnostics and Therapeutics

Huaxiu Zeng
Pooja Singh
Rajesh Sinha
Crystal T. Stephens
Aftab Ahmad
Mohammad Athar
Veena B. Antony

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644792

149 views

Original Research

Accepted on 29 Jul 2025

Identification and verification of biomarkers associated with neutrophils in acute myocardial infarction: Integrated analysis of bulk RNA-seq, expression quantitative trait loci, and Mendelian randomization

in Molecular Diagnostics and Therapeutics

Guoqing Liu
Xiangwen Lv
Jiahui Qin
Xingqing Long
Miaomiao Zhu
Chuwen Fu
Jian Xie
Peichun He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614350

Original Research

Accepted on 29 Jul 2025

CCDC138 Overexpression Predicts Poor Prognosis and Highlights Ciliopathy-Linked Mechanisms in Uterine Corpus Endometrial Carcinoma

in Molecular Diagnostics and Therapeutics

Fang Yang
Aiping Wang
Chunhua Zhang
Shi Li
Han Fu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1622496

Original Research

Published on 29 Jul 2025

Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation

in Molecular Diagnostics and Therapeutics

Xicheng Hu
Zhen Wang
Liyan Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1647796

223 views

Original Research

Accepted on 28 Jul 2025

Shared Transcriptional Regulators and Network Rewiring Identify Therapeutic Targets Linking Type 2 Diabetes Mellitus and Hypertension

in Molecular Diagnostics and Therapeutics

Claudia Desiree Norzagaray-Valenzuela
Marco Antonio Valdez-Flores
Josue Camberos-Barraza
Alberto De La Herrán-Arita
Juan Fidel Osuna-Ramos
Javier Magaña-Gómez
Carla Angulo-Rojo
Alma Marlene Guadron-Llanos
Katia Aviña-Padilla
Loranda Calderon-Zamora

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621413

109 views

Original Research

Accepted on 28 Jul 2025

Identification of kidney renal clear cell carcinoma prognosis based on gene expression and clinical information

in Molecular Diagnostics and Therapeutics

Xiong Zou
Xi Chen
Jianjun Yang
Yanfeng Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1630250

100 views

Original Research

Published on 28 Jul 2025

Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence

in Molecular Diagnostics and Therapeutics

Juan Chen
Lili Fu
Mengjin Li
Kun Xie
Xinming Li
Xu-jie Zhou
Li Yang
Liming Zhang
Cheng Xue
Zhiguo Mao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1627534

303 views

Opinion

Published on 25 Jul 2025

Immune surveillance as a pharmacological target in the early stages of cancer

in Molecular Diagnostics and Therapeutics

Hongfei Jiang
Zhun Wei
Haibo Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643024

592 views

Original Research

Published on 23 Jul 2025

Maternal plasma microRNA profiles in twin-twin transfusion syndrome and normal monochorionic twin pregnancies

in Molecular Diagnostics and Therapeutics

Steven T. Papastefan
Morgan M. Langereis
Catherine R. Redden
Daniel R. Liesman
Cassandra B. Huerta
Lucas E. Turner
Hee Kap Kang
Bethany T. Stetson
Katherine C. Ott
William S. Marriott

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1597215

368 views

Original Research

Published on 22 Jul 2025

TOP2A as a prognostic biomarker in small cell carcinoma of the esophagus: an integrated bioinformatics and immunohistochemical study

in Molecular Diagnostics and Therapeutics

Xiaolei Yin
Xiaopeng Li
Lili Mi
Jiaojiao Hou
Fei Yin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1640881

429 views

Review

Accepted on 21 Jul 2025

Molecular Mechanisms and Therapeutic Advances of Peritubular Capillary Neogenesis in Acute Kidney Injury

in Molecular Diagnostics and Therapeutics

Yuming Ding
Linmei Gao
yi chen
Yanheng Qiao
Bo Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643838

249 views

Review

Accepted on 21 Jul 2025

The Potential Role of Non-coding RNAs in Acute Kidney Injury: A Focus on Natural Medicine Treatment

in Molecular Diagnostics and Therapeutics

Yuxin GUO
Yanru ZHAO
Hanqing ZHANG
Yunze XING
Yaxuan FANG
Dingyuan ZHENG
Hanqi Yang
Yanheng Qiao
Bo Yang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648526

302 views

Original Research

Accepted on 19 Jul 2025

Preoperative Serum Inflammatory Markers in the Prognostic Assessment of Hepatocellular Carcinoma Resection in Stages I/II

in Molecular Diagnostics and Therapeutics

Fan Liu
Yuan Xiang
Hao Xu
Xiaoxue Xu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1640390

146 views

Original Research

Accepted on 18 Jul 2025

Comprehensive proteomic characterization of pulmonary arterial hypertension in Chinese people

in Molecular Diagnostics and Therapeutics

Tianya Liu
Sq Choy
Rui Wang
Xiaomei Xu
Fang Gao
Jie Zu
Zhiping Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1652083

Original Research

Published on 18 Jul 2025

Dynamic contrast-enhanced MRI-based radiomics model of intra-tumoral kinetic heterogeneity for predicting breast cancer molecular subtypes

in Molecular Diagnostics and Therapeutics

Yue Cheng
Ran Ren
Yu Xu
Shaofeng Duan
Jilei Zhang
Zhongyuan Bao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1635296

614 views

Review

Published on 17 Jul 2025

The role of epigenetics in pulmonary fibrosis: recent advances in mechanistic insights and therapeutic implications

in Molecular Diagnostics and Therapeutics

Jingru Huang
Jianfeng Qin
Yuguang Zhu
Ao Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1647300

799 views