Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 22 Sep 2025

Unleashing the immune modulatory potential of Leishmania amazonensis-derived extracellular vesicles in American cutaneous leishmaniasis

in Molecular Diagnostics and Therapeutics

Bruna Eugênia de Freitas
Armanda Rodrigues
Joana Palma-Marques
Juliana Inês Weber
Ana Valério-Bolas
Rodrigo Pedro Soares
Ana Claudia Torrecilhas
Micheli Ferla
Munira Muhammad Abdel Baqui
Raul Alexander Gonzales Cordova

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1593363

404 views

Review

Accepted on 19 Sep 2025

The role of antioxidants in facial nerve injury

in Molecular Diagnostics and Therapeutics

Jae Min Lee
Seong Wook Byun
Sung Soo Kim
Kyung Sun Park
Jae Hong Ryu
Seung Geun Yeo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1663998

153 views

Original Research

Accepted on 19 Sep 2025

Single-cell transcriptomics identifies an H2AFZ-driven proliferative tumor subpopulation associated with poor prognosis in hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Jihui Huo
Tao Yang
Kai Lei
Zeyao Wang
Zebin Chen
Qi Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1655705

213 views

Original Research

Accepted on 17 Sep 2025

Habitat imaging with intratumoral radiomics for prediction of axillary response after neoadjuvant chemotherapy in breast cancer patients

in Molecular Diagnostics and Therapeutics

Xiaomeng Ji
Bingxin Zhao
Yan Mao
Meng Lv
Yongmei Wang
Xiaohui Su
Zaixian Zhang
Jie Wu
Qi Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1684809

404 views

Correction

Published on 17 Sep 2025

Correction: The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

in Molecular Diagnostics and Therapeutics

Zixiang Liu
Pengpeng Li
Yuanhai Zhang
Shidi Zhao
Wei Gao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1692389

630 views

Original Research

Accepted on 16 Sep 2025

Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system

in Molecular Diagnostics and Therapeutics

Josiah T Wagner
John T Welle
Isabelle A Lucas Beckett
Kate R Emery
Benjamin A Cosgrove
Krzysztof Olszewski
Nick Wagner
Tucker C Bower
Li Chi Yuan
Eric M Shull

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1669085

362 views

Correction

Accepted on 12 Sep 2025

Correction: The protection of sulforaphane on subarachnoid hemorrhage-induced intestinal mucosa injury in rats

in Molecular Diagnostics and Therapeutics

Zixiang Liu
Wei Gao
Pengpeng Li
Yuanhai Zhang
Shidi Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1697320

552 views

Original Research

Accepted on 12 Sep 2025

Expression of Immune Related Genes and Possible Regulatory Mechanisms in Ulcerative Colitis

in Molecular Diagnostics and Therapeutics

Fanfan Qu
Baoqing Xu
Yi Zhou
Yang He
Yanda Wang
Jiaxin Li
Jiayin Li
Aihua Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1621643

615 views

Original Research

Accepted on 09 Sep 2025

Peripheral Circular RNAs hsa_circ_0075436 and hsa_circ_0005729 as Diagnostic and Prognostic Biomarkers in Acute Ischemic Stroke: Expression Profiles and Mechanistic Insights

in Molecular Diagnostics and Therapeutics

Wenqun Jiang
Weidong Chen
Shihao Lin
Pinpin Hou
Yichao Jin
Xiaohua Zhang
Hui Wu
Li Gao
Qin Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1657284

471 views

Original Research

Accepted on 09 Sep 2025

Clinical, phenotype and genotype correlations in primary ciliary dyskinesia suspected children in Egypt

in Molecular Diagnostics and Therapeutics

Rim Hjeij
Hoda Rizk
Mohammad Al-Haggar
Bernd Dworniczak
Dominik Otto
Heike Olbrich
Engy Osman
Heymut Omran
Tarek Eldesoky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1641739

410 views

Original Research

Published on 09 Sep 2025

Global research trends in metabolism-related intraocular malignancies: a multi-database bibliometric analysis and cross-validation study

in Molecular Diagnostics and Therapeutics

Jianhao Bai
Zhongqi Wan
Zhiyong Wu
Qing Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1683864

941 views

Original Research

Accepted on 08 Sep 2025

Identification of mitochondrial related gene characteristics and potential molecular mechanism of acute otitis media

in Molecular Diagnostics and Therapeutics

Dingjing Zi
Jing Hui
Leping Liang
Xiaoyong Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1642269

203 views

Original Research

Accepted on 08 Sep 2025

Elucidating the multiscale mechanisms and therapeutic targets of caffeic acid in gastric cancer: A synergy of computational and experimental approaches

in Molecular Diagnostics and Therapeutics

Hongrong Zhang
Yufan Li
Ya Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1663517

316 views

Review

Accepted on 05 Sep 2025

Fibrinogen Glycosylation and Glycation: Molecular Insights into Thrombosis and Vascular Disease

in Molecular Diagnostics and Therapeutics

Serena Borghi
Francesca Nencini
Elvira Giurranna
Ilenia Barbaro
Niccolò Taddei
Claudia Fiorillo
Matteo Becatti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1680332

334 views

Original Research

Published on 03 Sep 2025

Increased serum anti-ceramide antibodies and decreased sphingosine-1-phosphate levels in patients with obstructive sleep apnea syndrome as potential markers of endothelial dysfunction

in Molecular Diagnostics and Therapeutics

Andrzej Wiśniewski
Elżbieta Wiśniewska
Łukasz Lewandowski
Izabela Nowak
Monika Kosacka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1644828

1,111 views

Original Research

Published on 03 Sep 2025

Establishment and application of a preset dilution factor strategy for human chorionic gonadotropin testing in clinical laboratory

in Molecular Diagnostics and Therapeutics

Shu Chen
Qin Li
Huaqiang Liao
Mingcai Zhao
Jie Chen
Hongyu Chen
Guangjun Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1648421

1,077 views