Frontiers in Molecular Neuroscience

Original Research

Published on 13 Feb 2025

Deciphering motor dysfunction and microglial activation in mThy1-α-synuclein mice: a comprehensive study of behavioral, gene expression, and methylation changes

in Brain Disease Mechanisms

Brett A. McGregor
Md. Obayed Raihan
Afrina Brishti
Junguk Hur
James E. Porter

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1544971

815 views

Review

Published on 13 Feb 2025

Extrinsic and intrinsic control of striatal cholinergic interneuron activity

in Molecular Signalling and Pathways

Desh Deepak Ratna
Tanner Chase Francis

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1528419

1,517 views

Review

Published on 11 Feb 2025

The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders

in Brain Disease Mechanisms

Sean D. Fraser
Robert J. Harvey

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1550863

1,732 views

Editorial

Published on 07 Feb 2025

Editorial: Spatio-temporal molecular mechanisms regulating synapse function and neural circuit dynamics

in Neuroplasticity and Development

Tomohisa Hosokawa
Yoshiyuki Kubota
Tetsuya Takano

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564028

897 views

Editorial

Published on 06 Feb 2025

Editorial: Latest advances in neuroscience at the 9th Croatian Neuroscience Congress

in Neuroplasticity and Development

Kristina Mlinac-Jerkovic
Marija Heffer
Svjetlana Kalanj-Bognar
Senka Blažetić

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563899

768 views

Mini Review

Published on 05 Feb 2025

GPCRs in hypothalamic neurons and their roles in controlling food intake and metabolism

in Molecular Signalling and Pathways

Tian Qiu
Ou Fu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1536577

1,593 views

Original Research

Published on 05 Feb 2025

The effect of AKT inhibition in α-synuclein-dependent neurodegeneration

in Brain Disease Mechanisms

Bedri Ranxhi
Zoya R. Bangash
Zachary M. Chbihi
Sokol V. Todi
Peter A. LeWitt
Wei-Ling Tsou

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1524044

1,283 views
1 citation

Original Research

Published on 05 Feb 2025

Ectopic expression of the cation-chloride cotransporter KCC2 in blood exosomes as a biomarker for functional rehabilitation

in Brain Disease Mechanisms

L. Caccialupi Da Prato
A. Rezzag Lebza
A. Consumi
M. Tessier
A. Srinivasan
C. Rivera
J. Laurin
C. Pellegrino

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1522571

959 views

Editorial

Published on 04 Feb 2025

Editorial: Nervous regeneration and functional recovery in the central and peripheral nervous systems: diagnostic methods, gene/cell therapies, and interventions

in Molecular Signalling and Pathways

Dipa Natarajan
Ryo Hotta
Naho Fujiwara
Silvia Perin

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1555390

686 views

Original Research

Published on 03 Feb 2025

Clinicopathological and molecular characterization of astrocytoma

in Molecular Signalling and Pathways

Xiaoyan Wu
Wenfeng Peng
Xu Zhang
Tao Tang
Ling Deng
Yuxia Xu
Xiaoyun Liu
Fang Wang
Wujian Peng
Jianrong Huang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1483833

955 views

Original Research

Published on 30 Jan 2025

Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes

in Molecular Signalling and Pathways

Ali Tawbeh
Catherine Gondcaille
Fatima-Ezzahra Saih
Quentin Raas
Damien Loichot
Yannick Hamon
Céline Keime
Alexandre Benani
Francesca Di Cara
Mustapha Cherkaoui-Malki

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1542938

1,823 views

Original Research

Published on 29 Jan 2025

Short- and long-term changes in neurological, behavioural, and blood biomarkers following repeated mild traumatic brain injury in rats—potential biological sex-dependent effects

in Brain Disease Mechanisms

Rodrigo Moraga-Amaro
Oscar Moreno
Jordi Llop
Marion Bankstahl
Jens P. Bankstahl

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1488261

1,349 views

Review

Published on 27 Jan 2025

Regulatory mechanism of Reelin activity: a platform for exploiting Reelin as a therapeutic agent

in Brain Disease Mechanisms

Mitsuharu Hattori

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1546083

1,769 views
2 citations

Original Research

Published on 22 Jan 2025

A localized tracing technique to explore intra-amygdala functional and structural correlates of individual variability in behavioral response

in Neuroplasticity and Development

Allie Lipshutz
Victoria Saltz
Kristin R. Anderson
Alessia Manganaro
Dani Dumitriu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1347539

879 views

Review

Published on 22 Jan 2025

Brain network and energy imbalance in Parkinson’s disease: linking ATP reduction and α-synuclein pathology

in Molecular Signalling and Pathways

Hirohisa Watanabe
Sayuri Shima
Kazuya Kawabata
Yasuaki Mizutani
Akihiro Ueda
Mizuki Ito

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1507033

2,219 views
1 citation

Original Research

Published on 21 Jan 2025

Nicotinic α7 receptors on cholinergic neurons in the striatum mediate cocaine-reinforcement, but not food reward

in Molecular Signalling and Pathways

Michael Fritz
Priscila Batista Rosa
Daniel Wilhelms
Maarit Jaarola
Johan Ruud
David Engblom
Anna M. Klawonn

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2024.1418686

1,771 views