Frontiers in Molecular Neuroscience | Brain Disease Mechanisms

Systematic Review

Published on 02 Jul 2025

Recognition of the microbial metabolite p-cresol in autism spectrum disorder: systematic review and meta-analysis

in Brain Disease Mechanisms

María Isabel Serrano-Tomás
Paulina Contreras-Romero
Mara Parellada
Javier Chaves-Cordero
Javier Zamora
Martha Hengst
Patricia Pozo
Rosa del Campo
Sheyla Guzmán-Salas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1576388

509 views

Original Research

Accepted on 30 Jun 2025

Chronic reduction of synaptic proteins in the epileptogenic lesion of patients with hippocampal sclerosis

in Brain Disease Mechanisms

Akiko Oota-Ishigaki
Nami Suzuki
Keiya Iijima
Yutaro Takayama
Yuiko Kimura
Kotaro Hattori
Masaki Iwasaki
Takashi Hayashi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1635852

Review

Published on 26 Jun 2025

Mechanism of heme oxygenase-1 regulation of ferroptosis in vascular dementia

in Brain Disease Mechanisms

Xin-yi Zou
Luo-yang Cai
Jin Zhang
Ying Yuan
Jie Song
Zhao-duan Hu
Xiao-feng Ruan
Rui Peng
Xiao-ming Zhang

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1585079

414 views

Original Research

Accepted on 25 Jun 2025

The role of BET inhibition in modulating amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation

in Brain Disease Mechanisms

Marta Matuszewska
Anna Wilkaniec
Magdalena Gąssowska-Dobrowolska
Magdalena Cieślik
Gabriela Olech-Kochańczyk
Ewelina Pałasz
Elżbieta Gawinek
Marcin Strawski
Grzegorz Arkadiusz Czapski

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1619583

124 views

Original Research

Published on 25 Jun 2025

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke

in Brain Disease Mechanisms

Rui Mao
Lei Wang
Haitao Zhang
Jiaojiao Gong
Hua Liu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1604670

351 views

Review

Published on 25 Jun 2025

How endothelial cell metabolism shapes blood–brain barrier integrity in neurodegeneration

in Brain Disease Mechanisms

Jiaxin Wang
Yuchun Chen
Shiteng Chen
Zihan Mu
Jun Chen

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1623321

467 views

Original Research

Published on 25 Jun 2025

Whole-genome sequencing shows modulation of neurodegenerative genes by Withania somnifera in human SK-N-SH cells

in Brain Disease Mechanisms

Eshita Sharma
Dilip Mehta
Nikita Jadhav
Gunjan Gujrati
S. Dhananya
Manju Moorthy
Gopalakrishna Ramaswamy
Yundong Zhou
Sujit Nair

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1512727

651 views

Original Research

Published on 18 Jun 2025

Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance

in Brain Disease Mechanisms

Qingqing Xu
Xin Liu
Yibo Zhang
Shiyu Yuan
Wenli Huang
Mingshan Pi
Qi Xiong
Hongyan Zhou
Yuran Gui
Yifan Xiao

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1596021

557 views

Review

Accepted on 12 Jun 2025

Role of the Chaperonin TCP-1 Ring Complex (TRiC) in Protein Aggregation and Neurodegeneration

in Brain Disease Mechanisms

Vanlalrinchhani Varte
Diego E Rincon-Limas

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1617771

178 views

Original Research

Published on 27 May 2025

Exposure to a nanoplastic-enriched diet for fourteen days increases microglial immunoreactivity in the zebrafish telencephalon

in Brain Disease Mechanisms

Robert A. Mans
Hannah Kelehear
Sarah Rotschafer
Clare Ganas
Brendan Uche-Moon
Gabrielle Call
Callie C. Mauersberg
Justin Toller
Andrew Diamanduros

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1563086

1,522 views

Mini Review

Published on 16 May 2025

Regulatory mechanism of circular RNAs in brain and neurodegenerative diseases

in Brain Disease Mechanisms

Mandana Amelimojarad
Melika Amelimojarad

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1507575

1,028 views

Original Research

Published on 09 May 2025

Changes in glycinergic neurotransmission alter mammalian retinal information processing

in Brain Disease Mechanisms

Anneka Joachimsthaler
Katharina Hauf
Anja Armbruster
Shiri Zayit-Soudry
Efrat Naaman
Ido Perlman
Rina Leibu
Alina Kurolap
Hagit Baris Feldman
Jan Kremers

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1564870

1,063 views

Editorial

Published on 08 May 2025

Editorial: SLC12A5-dependent neurological disorders

in Brain Disease Mechanisms

Igor Medina
Amy McTague
Coralie Di Scala
Claudio Rivera

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1611682

1,039 views

Review

Published on 01 May 2025

NFE2L1 as a central regulator of proteostasis in neurodegenerative diseases: interplay with autophagy, ferroptosis, and the proteasome

in Brain Disease Mechanisms

Hossein Khodadadi
Kamila Łuczyńska
Dawid Winiarczyk
Paweł Leszczyński
Hiroaki Taniguchi

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1551571

1,614 views

Editorial

Published on 30 Apr 2025

Editorial: Neuro-immune interplay: unraveling the complexities of neurological complications and immunology

in Brain Disease Mechanisms

Pankaj Gaur
Kumar Vaibhav
Meenakshi Ahluwalia
Seema Gupta

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1607675

1,191 views
1 citation

Original Research

Published on 28 Apr 2025

Traumatic brain injury and autophagy: a pilot study about the immunohistochemical expression of LC3B, Beclin 1, p62, and LAMP2A in human autoptic samples

in Brain Disease Mechanisms

Tommaso Livieri
Letizia Alfieri
Emiliana Giacomello
Djordje Alempijević
Tijana Petrovic
Yanko Georgiev Kolev
Davide Radaelli
Margherita Neri
Stefano D’Errico

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1562954

1,356 views