Frontiers in Natural Products | Isolation and Purification

Original Research

Published on 05 Oct 2026

Isolation and identification of a new biflavonoid from the Amazonian tree Ceiba pentandra (L.) Gaertn. (sumaúma)

in Isolation and Purification

Priscila Brasil Augusto de Souza
Davi Santos Oliveira
Estefane de Oliveira Picanço
Magno Perêa Muniz
Claudete Catanhede do Nascimento
Maria da Paz Lima

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1888758

749 views

Original Research

Published on 25 Sep 2026

Quality by design driven development of a Monteverdia ilicifolia herbal medicine: from plant to granules

in Isolation and Purification

Alberto Araujo de Caux
José Cláudio Klier Monteiro Filho
Ruan Barbosa da Silva e Medeiros
Marili Villa Nova Rodrigues
Marcos Nopper Alves
Marcus Bruno Soares Forte
Maria Isabel Rodrigues
Rodney Alexandre Ferreira Rodrigues

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1887810

796 views

Original Research

Published on 23 Sep 2026

Supercritical CO2 extraction of Phoradendron leucarpum (American mistletoe): optimizing oleanolic acid and polyphenol yields, monitoring ROS-specific neutralization

in Isolation and Purification

Fatemeh Ijadi
Tomás J. Buenfil-Chi
Delia A. Serna Guerrero
H. Mercado-Uribe
Daniel Guajardo-Flores
Francisco Javier Sierra-Valdez

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1931234

530 views

Original Research

Accepted on 26 Aug 2026

Triterpenoid Constituents from the Branches of Monteverdia acanthophylla

in Isolation and Purification

Rafael do Prado Gomes
Brisa Souza
Maria Jardim
Adriano Sabino
Lucienir Duarte
Grasiely Sousa

Frontiers in Natural Products

402 views

Mini Review

Published on 17 Aug 2026

Natural cyclopeptides from Rubiaceae: advances from the last decade

in Isolation and Purification

Pedro Henrique Jatai Batista
Matheus Lopes Silva
Cássia Gonçalves Magalhães

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1886868

857 views

Brief Research Report

Published on 06 Aug 2026

Physicochemical characterization and metabolomic analysis of green coffee oil from Coffea arabica L. cultivated in Bahia, Brazil

in Isolation and Purification

Jayne Ferreira da Silva Oliveira
Paulinne Moreira Lima
Maria Alice Sousa Marinho
Micaela Sousa Coutinho Silva
Lara Beatriz de Andrade Silva
Isabela Dias dos Santos
Bruna Santana Neves
Anderson Santos Souza
Gabriel Azevedo de Brito Damasceno
Juliano Geraldo Amaral

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1886822

841 views

Review

Published on 29 Jul 2026

Bioactive constituents of Hericium erinaceus: extraction strategies, health benefits and food applications

in Isolation and Purification

Vibhuti Gurung
Narashans Alok Sagar
Nitu Rani

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1872464

4,704 views

Editorial

Published on 18 Feb 2026

Editorial: Innovative approaches in isolation and purification: balancing efficiency and sustainability

in Isolation and Purification

Mostafa E. Rateb
Abdelbasset Chafik
Usama Ramadan Abdelmohsen

Frontiers in Natural Products

doi 10.3389/fntpr.2026.1793176

1,423 views
1 citation

Original Research

Published on 12 Jan 2026

Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: the case of Combretum micranthum

in Isolation and Purification

Lisa Vuadens
Robin Huber
Laurence Marcourt
Luis-Manuel Quiros-Guerrero
Olivier Auguste Kirchhoffer
Arnaud Gaudry
Renata Campos Nogueira
Elhadji Assane Diop
Sidi Mohamed Seck
Jean-Luc Wolfender

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1717575

2,967 views

Brief Research Report

Published on 16 Dec 2025

Workflow for the isolation of natural product secondary metabolites using off-line SPE guided by gradient reverse-phase liquid chromatography (LCSPE-fast)

in Isolation and Purification

Lyamara M. O. Pavão
Marília F. Barbosa
Ana Maria S. Pereira
Quezia B. Cass
Adriana A. Lopes

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1726849

3,034 views

Original Research

Published on 17 Nov 2025

Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars

in Isolation and Purification

Tedi Rustandi
Fakhriah Hayati
Fatah Nugroho
Senya Puteri Amalia
Regina Nastasya
Ahmed Mahal

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1694933

2,514 views
1 citation

Review

Published on 31 Oct 2025

The chemistry of flavonoids from Annonaceae: a comprehensive review

in Isolation and Purification

Igor R. S. Graça
Matheus V. N. Belém
Maria L. B. Pinheiro
Felipe M. A. Da Silva
Hector H. F. Koolen

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1657095

5,576 views
6 citations

Review

Published on 17 Apr 2025

Exploring the therapeutic potential of essential oils: a review of composition and influencing factors

in Isolation and Purification

Usama Ramadan Abdelmohsen
Abeer H. Elmaidomy

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1490511

16,128 views
59 citations

Review

Published on 13 Mar 2025

A critical review on purification methods and applications of marine algal haloperoxidases

in Isolation and Purification

Abdellatif Rahim
Rania Benjamaa
Abdel Khalid Essamadi
Abdelbasset Chafik

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1537097

5,090 views
3 citations

Methods

Published on 24 Jan 2025

MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research

in Isolation and Purification

Zeinab G. Khalil
Thulasi Sritharan
Angela A. Salim
Robert J. Capon

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1532543

4,441 views
2 citations

Mini Review

Published on 07 Jan 2025

Methods of saponin purification from Quillaja sp. for vaccine adjuvant production

in Isolation and Purification

Victor Morais
Norma Suarez
Fernando Silveira

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1524624

8,076 views
6 citations

Review

Published on 20 Sep 2024

Adopting biorefinery and a circular bioeconomy for extracting and isolating natural products from marine algae

in Isolation and Purification

Ahmed Zayed
Hosam M. El-Seadawy
Eman Zekry Attia
Mohammed I. Rushdi
Usama Ramadan Abdelmohsen

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1425242

9,262 views
20 citations

Original Research

Published on 28 Mar 2024

A study of the protease inhibitory activity component of SARS-CoV-2 3CL in Bletilla striata

in Isolation and Purification

Yuyu Yang
Fei Zhang
Shihan Liu
Wenfang Jin
Qianshan Shao
Chunxiao Li
Baolei Fan

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1372623

3,899 views
2 citations

Review

Published on 13 Sep 2023

Twenty-five years of natural products research in NuBBE

in Isolation and Purification

Helena Mannochio-Russo
Ana Letícia Pires dos Santos
Paula Carolina Pires Bueno
Rafael Vieira
Meri Emili Ferreira Pinto
Suzana Aparecida Silva Queiroz
Luiz Antonio Dutra
Lidiane Gaspareto Felippe
Andrea Nastri de Luca Batista
Tatiana Maria de Souza-Moreira

Frontiers in Natural Products

doi 10.3389/fntpr.2023.1252092

8,120 views
4 citations

Original Research

Published on 10 Aug 2023

LC-MS guided isolation of N,β-glucopyranosyl vincosamide and other compounds from the curare ingredient Strychnos peckii

in Isolation and Purification

Carla L. G. Santos
Kidney O. G. Neves
Francinaldo A. Silva-Filho
Bruna R. Lima
Emmanoel V. Costa
Afonso D. L. de Souza
Hector H. F. Koolen
Maria Lúcia B. Pinheiro
Felipe M. A. da Silva

Frontiers in Natural Products

doi 10.3389/fntpr.2023.1189619

3,585 views
6 citations

Original Research

Published on 06 Jan 2023

Gambogic acid: Multi-gram scale isolation, stereochemical erosion toward epi-gambogic acid and biological profile

in Isolation and Purification

Gary E. Arevalo
Michelle K. Frank
Katelin S. Decker
Maria A. Theodoraki
Emmanuel A. Theodorakis

Frontiers in Natural Products

doi 10.3389/fntpr.2022.1018765

5,512 views
3 citations

Review

Published on 28 Nov 2022

Comprehensive comparison of industrial cannabinoid extraction techniques: Evaluation of the most relevant patents and studies at pilot scale

in Isolation and Purification

Cristina López-Olmos
María Teresa García-Valverde
Jesús Hidalgo
Carlos Ferrerio-Vera
Verónica Sánchez de Medina

Frontiers in Natural Products

doi 10.3389/fntpr.2022.1043147

44,003 views
33 citations

Original Research

Published on 18 Oct 2022

A structure-activity relationship analysis of anthraquinones with antifouling activity against marine biofilm-forming bacteria

in Isolation and Purification

Gagan Preet
Jessica Gomez-Banderas
Rainer Ebel
Marcel Jaspars

Frontiers in Natural Products

doi 10.3389/fntpr.2022.990822

8,751 views
10 citations

Specialty Grand Challenge

Published on 19 May 2022

Natural Products’ Extraction and Isolation-Between Conventional and Modern Techniques

in Isolation and Purification

Usama Ramadan Abdelmohsen
Ahmed M. Sayed
Abeer H. Elmaidomy

Frontiers in Natural Products

doi 10.3389/fntpr.2022.873808

35,074 views
38 citations

24 articles

articles

Isolation and identification of a new biflavonoid from the Amazonian tree Ceiba pentandra (L.) Gaertn. (sumaúma)

Quality by design driven development of a Monteverdia ilicifolia herbal medicine: from plant to granules

Supercritical CO2 extraction of Phoradendron leucarpum (American mistletoe): optimizing oleanolic acid and polyphenol yields, monitoring ROS-specific neutralization

Triterpenoid Constituents from the Branches of Monteverdia acanthophylla

Natural cyclopeptides from Rubiaceae: advances from the last decade

Physicochemical characterization and metabolomic analysis of green coffee oil from Coffea arabica L. cultivated in Bahia, Brazil

Bioactive constituents of Hericium erinaceus: extraction strategies, health benefits and food applications

Editorial: Innovative approaches in isolation and purification: balancing efficiency and sustainability

Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: the case of Combretum micranthum

Workflow for the isolation of natural product secondary metabolites using off-line SPE guided by gradient reverse-phase liquid chromatography (LCSPE-fast)

Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars

The chemistry of flavonoids from Annonaceae: a comprehensive review

Exploring the therapeutic potential of essential oils: a review of composition and influencing factors

A critical review on purification methods and applications of marine algal haloperoxidases

MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research

Methods of saponin purification from Quillaja sp. for vaccine adjuvant production

Adopting biorefinery and a circular bioeconomy for extracting and isolating natural products from marine algae

A study of the protease inhibitory activity component of SARS-CoV-2 3CL in Bletilla striata

Twenty-five years of natural products research in NuBBE

LC-MS guided isolation of N,β-glucopyranosyl vincosamide and other compounds from the curare ingredient Strychnos peckii

Gambogic acid: Multi-gram scale isolation, stereochemical erosion toward epi-gambogic acid and biological profile

Comprehensive comparison of industrial cannabinoid extraction techniques: Evaluation of the most relevant patents and studies at pilot scale

A structure-activity relationship analysis of anthraquinones with antifouling activity against marine biofilm-forming bacteria

Natural Products’ Extraction and Isolation-Between Conventional and Modern Techniques