Frontiers in Natural Products | Isolation and Purification

Brief Research Report

Accepted on 30 Nov 2025

Workflow for the Isolation of Natural Product Secondary Metabolites Using Off-Line SPE Guided by Gradient Reverse-Phase Liquid Chromatography (LCSPE-fast)

in Isolation and Purification

Lyamara M. O. Pavão
Marília F. Barbosa
Ana Maria Soares Pereira
Quezia B. Cass
Adriana Aparecida Lopes

Frontiers in Natural Products

142 views

Original Research

Published on 17 Nov 2025

Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars

in Isolation and Purification

Tedi Rustandi
Fakhriah Hayati
Fatah Nugroho
Senya Puteri Amalia
Regina Nastasya
Ahmed Mahal

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1694933

586 views

Original Research

Accepted on 14 Nov 2025

Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: The case of Combretum micranthum

in Isolation and Purification

Lisa Vuadens
Robin Huber
Laurence Marcourt
Luis Manuel Quiros-Guerrero
Olivier Kirchhoffer
Arnaud Gaudry
Renata Campos Nogueira
Elhadji Assane Diop
Sidy Mohamed Seck
Wolfender Jean-Luc

Frontiers in Natural Products

172 views

Review

Published on 31 Oct 2025

The chemistry of flavonoids from Annonaceae: a comprehensive review

in Isolation and Purification

Igor R. S. Graça
Matheus V. N. Belém
Maria L. B. Pinheiro
Felipe M. A. Da Silva
Hector H. F. Koolen

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1657095

1,134 views

Review

Published on 17 Apr 2025

Exploring the therapeutic potential of essential oils: a review of composition and influencing factors

in Isolation and Purification

Usama Ramadan Abdelmohsen
Abeer H. Elmaidomy

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1490511

7,792 views
9 citations

Review

Published on 13 Mar 2025

A critical review on purification methods and applications of marine algal haloperoxidases

in Isolation and Purification

Abdellatif Rahim
Rania Benjamaa
Abdel Khalid Essamadi
Abdelbasset Chafik

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1537097

3,061 views

Methods

Published on 24 Jan 2025

MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research

in Isolation and Purification

Zeinab G. Khalil
Thulasi Sritharan
Angela A. Salim
Robert J. Capon

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1532543

2,330 views
1 citation

Mini Review

Published on 07 Jan 2025

Methods of saponin purification from Quillaja sp. for vaccine adjuvant production

in Isolation and Purification

Victor Morais
Norma Suarez
Fernando Silveira

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1524624

4,266 views
2 citations

Review

Published on 20 Sep 2024

Adopting biorefinery and a circular bioeconomy for extracting and isolating natural products from marine algae

in Isolation and Purification

Ahmed Zayed
Hosam M. El-Seadawy
Eman Zekry Attia
Mohammed I. Rushdi
Usama Ramadan Abdelmohsen

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1425242

5,285 views
10 citations

Original Research

Published on 28 Mar 2024

A study of the protease inhibitory activity component of SARS-CoV-2 3CL in Bletilla striata

in Isolation and Purification

Yuyu Yang
Fei Zhang
Shihan Liu
Wenfang Jin
Qianshan Shao
Chunxiao Li
Baolei Fan

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1372623

2,550 views
2 citations

Review

Published on 13 Sep 2023

Twenty-five years of natural products research in NuBBE

in Isolation and Purification

Helena Mannochio-Russo
Ana Letícia Pires dos Santos
Paula Carolina Pires Bueno
Rafael Vieira
Meri Emili Ferreira Pinto
Suzana Aparecida Silva Queiroz
Luiz Antonio Dutra
Lidiane Gaspareto Felippe
Andrea Nastri de Luca Batista
Tatiana Maria de Souza-Moreira

Frontiers in Natural Products

doi 10.3389/fntpr.2023.1252092

5,035 views
3 citations

Original Research

Published on 10 Aug 2023

LC-MS guided isolation of N,β-glucopyranosyl vincosamide and other compounds from the curare ingredient Strychnos peckii

in Isolation and Purification

Carla L. G. Santos
Kidney O. G. Neves
Francinaldo A. Silva-Filho
Bruna R. Lima
Emmanoel V. Costa
Afonso D. L. de Souza
Hector H. F. Koolen
Maria Lúcia B. Pinheiro
Felipe M. A. da Silva

Frontiers in Natural Products

doi 10.3389/fntpr.2023.1189619

2,163 views
4 citations

Original Research

Published on 06 Jan 2023

Gambogic acid: Multi-gram scale isolation, stereochemical erosion toward epi-gambogic acid and biological profile

in Isolation and Purification

Gary E. Arevalo
Michelle K. Frank
Katelin S. Decker
Maria A. Theodoraki
Emmanuel A. Theodorakis

Frontiers in Natural Products

doi 10.3389/fntpr.2022.1018765

3,588 views
3 citations

Review

Published on 28 Nov 2022

Comprehensive comparison of industrial cannabinoid extraction techniques: Evaluation of the most relevant patents and studies at pilot scale

in Isolation and Purification

Cristina López-Olmos
María Teresa García-Valverde
Jesús Hidalgo
Carlos Ferrerio-Vera
Verónica Sánchez de Medina

Frontiers in Natural Products

doi 10.3389/fntpr.2022.1043147

33,361 views
20 citations

Original Research

Published on 18 Oct 2022

A structure-activity relationship analysis of anthraquinones with antifouling activity against marine biofilm-forming bacteria

in Isolation and Purification

Gagan Preet
Jessica Gomez-Banderas
Rainer Ebel
Marcel Jaspars

Frontiers in Natural Products

doi 10.3389/fntpr.2022.990822

6,733 views
8 citations

Specialty Grand Challenge

Published on 19 May 2022

Natural Products’ Extraction and Isolation-Between Conventional and Modern Techniques

in Isolation and Purification

Usama Ramadan Abdelmohsen
Ahmed M. Sayed
Abeer H. Elmaidomy

Frontiers in Natural Products

doi 10.3389/fntpr.2022.873808

28,694 views
31 citations