Frontiers in Neuroscience | Gut-Brain Axis

Original Research

Accepted on 14 Oct 2025

Exploring Gut Microbiota Alterations in Parkinson's Disease: Insights from a 16S Amplicon Sequencing Eastern European Pilot Study

in Gut-Brain Axis

Ovidiu Dumitru Ilie
Irina Cezara Văcărean-Trandafir2
Roxana-Maria Amărandi
Ilinca Bianca Nita (Ilie)
Petru-Romeo Dobrin
Mara Doroftei
Iuliu Cristian Ivanov
Gheorghe Savuta
Boris Kirov
Bogdan Doroftei

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1654995

167 views

Brief Research Report

Published on 01 Oct 2025

Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: implications for Parkinson’s disease pathogenesis

in Gut-Brain Axis

Elisa Menozzi
Mallia Geiger
Victoria Meslier
Federico Fierli
Marine Gilles
Kai-Yin Chau
Aymeric David
Revi Shahar Golan
Alexandre Famechon
Sofia Koletsi

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1546203

1,579 views

Original Research

Accepted on 24 Sep 2025

Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster

in Gut-Brain Axis

Florance Parweez
Roger Palou
Ruizhen Li
Lanna Kadhim
Heath MacMillan
Mike Tyers
X. Johne Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1628160

892 views

Original Research

Published on 22 Sep 2025

Neuroprotective effects of bavachalcone in a mouse model of Parkinson’s disease: linking the gut-brain axis and systemic metabolism

in Gut-Brain Axis

Shuai Shi
Xiaohan Bian
Mengyun Li
Xiaobing Zhang
Wenji Huang
Xian Shao
Tiantian Lu
Xuebin Yu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1650288

3,280 views

Editorial

Published on 03 Sep 2025

Editorial: Reviews in gut-brain axis: stress, dysregulation in gut-brain axis function and stress related disorders

in Gut-Brain Axis

Zuleide Maria Ignácio
Jonathan B. Clayton
Margarete Dulce Bagatini
Avinash Veerappa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1665282

3,062 views

Original Research

Published on 02 Sep 2025

Neurofunctional correlates of emotional dysregulation in adolescent Crohn’s disease: a resting-state fMRI preliminary investigation

in Gut-Brain Axis

Ao Liu
Mengting Huang
Xiaoling Deng
Shuo Huang
Keshu Xu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1622708

2,943 views

Systematic Review

Published on 20 Aug 2025

Safety and efficacy of fecal microbiota transplantation in the treatment of Parkinson’s disease: a systematic review of clinical trials

in Gut-Brain Axis

Kewei Chen
Lirong Sun
Yilan Liu
Ran Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1639911

3,107 views
1 citation

Original Research

Published on 13 Aug 2025

Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study

in Gut-Brain Axis

Po-Chun Liu
Shao-Ying Cheng
Chih-Chi Li
Yu-Ke Wang
Yufeng Jane Tseng
Ming-Che Kuo

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1623165

2,039 views

Original Research

Published on 24 Jul 2025

Gut microbiota regulates innate anxiety through neural activity of medial prefrontal cortex in male mice

in Gut-Brain Axis

Jing Ren
Xiao-Ying Lian
Wan-Qian Ye
You-Lu Wen
Cheng-Lin Lu
Xiong Cao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1599818

2,584 views

Original Research

Published on 23 Jul 2025

Does constipation affect the effectiveness of washed microbiota transplantation in treating autism spectrum disorders?

in Gut-Brain Axis

Zihao Pan
Zheng Gao
Junyi Chen
Yongxi Quan
Jiating Xu
Xiaofeng Liang
Wenrui Xie
Xingxiang He
Lihao Wu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1602681

2,065 views

Review

Published on 16 Jul 2025

Research progress on immunometabolism and gut microbiota in cryptococcal meningitis: mechanisms and therapeutic implications

in Gut-Brain Axis

Sha Wen
Mu Liu
Chengyu Pan
Linhai Zhang
Rong Yan
Zucai Xu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1622349

2,968 views

Review

Published on 15 Jul 2025

Intestinal ischemia–reperfusion and blood–brain barrier compromise: pathways to cognitive dysfunction

in Gut-Brain Axis

Opeyemi Hammed
Oladele Afolabi
Richard Ajike
Oluwaseun Hezekiah
Babatunde Alabi
David Ajao
Waidi Saka
Olubunmi Oyekunle
Bamidele Olusola

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1597170

2,449 views

Mini Review

Published on 10 Jul 2025

Gut microbiota and stress ulcers: unraveling the neurotransmitter connection

in Gut-Brain Axis

Khaled A. Abdel-Sater
Heba A. Hassan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1594179

2,288 views
1 citation

Review

Published on 08 Jul 2025

Gut microbiota and sepsis-associated encephalopathy: pathogenesis and precision therapies

in Gut-Brain Axis

Na Wei
Shiyu Dai
Wei Li
Jun Zhou
Ye Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1596467

2,706 views

Original Research

Published on 19 Jun 2025

Research on the correlation between gut microbiota and brain cognitive function under chronic hypoxia at high altitude

in Gut-Brain Axis

Feng Zeng
Hanxue Li
Yan Ma
Shuang Ma

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1600069

2,353 views

Original Research

Published on 18 Jun 2025

A magnetic resonance imaging and gut flora-based study of intake desire in overweight/obese type 2 diabetes mellitus patients

in Gut-Brain Axis

Mingxuan Gao
Liya Gong
Yanmei Zeng
Dongling Li
Junyan Wen
Ying Guo
Zhujia Li
Jingwen Luo
Chunling Chen
Ge Wen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1612722

1,530 views