Frontiers in Neuroscience | Neurodegeneration

Original Research

Published on 03 Jul 2025

Gait dynamics and brain function abnormalities in Parkinson’s disease with freezing of gait: a clinical study using resting-state fMRI and wearable devices

in Neurodegeneration

Xiaohong Li
Mengdi Hou
Yan Qu
Yuan Huo
Shuting Liu
Minghui Ma
Zhanhua Liang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1560333

207 views

Original Research

Published on 03 Jul 2025

Alpha-synuclein null mutation exacerbates the phenotype of a model of Menkes disease in female mice

in Neurodegeneration

MegAnne Casey
Dan Zou
Renee A. Reijo Pera
Tiffany Hensley-McBain
Deborah E. Cabin

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1613171

190 views

Correction

Published on 01 Jul 2025

Correction: Reduction of the RNA binding protein TIA1 exacerbates neuroinflammation in tauopathy

in Neurodegeneration

Chelsey Jenna LeBlang
Maria Medalla
Nicholas William Nicoletti
Emma Catherine Hays
James Zhao
Jenifer Shattuck
Anna Lourdes Cruz
Benjamin Wolozin
Jennifer Irene Luebke

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1641304

219 views

Editorial

Published on 30 Jun 2025

Editorial: Progress in neuroacanthocytosis syndromes and related diseases including other bulk lipid transfer disorders

in Neurodegeneration

Adrian Danek
Andreas Hermann
Lars Kaestner
Mercè Masana
Kevin Peikert
Manuel J. Rodriguez
Ruth H. Walker

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1635008

336 views

Case Report

Published on 27 Jun 2025

Case Report: Role of hypoglycemia in seizure aggravation in a case of focal epilepsy: revealing a missing link between diabetes and dementia

in Neurodegeneration

Hiroya Ohara
Masami Yamanaka
Kiyoko Inoue
Hironori Shimizu
Naohiko Iguchi
Keiko Tanaka
Abilash Valsala Gopalakrishnan
Balachandar Vellingiri
Masako Kinoshita

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1604552

697 views

Original Research

Accepted on 26 Jun 2025

Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

in Neurodegeneration

Manpreet Singh Atwal
Urša Čerček
Sarah Ricarda Goesch
Hannah Rebecca Goesch
Ivo Carre
Paraskevi Tziortzouda
Anna Zatorska
Terouz Pasha
Jacqueline Clare Mitchell
Claire Troakes

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1558227

214 views

Original Research

Accepted on 26 Jun 2025

Thalamic nuclei volumes are related to disease stage in patients with amyotrophic lateral sclerosis

in Neurodegeneration

Tianrui Wen
Jun Zhu
Sujuan Sun
Yujing Chen
Ninglu Gao
Mingjie Ma
Xinyue Chen
Shuangwu Liu
Pengfei Lin
Yan Deng

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1616239

144 views

Review

Accepted on 25 Jun 2025

Dravet Syndrome: Novel Insights into SCN1A-Mediated Epileptic Neurodevelopmental Disorders within the Molecular Diagnostic-Therapeutic Framework

in Neurodegeneration

Jin Wang
Guirui Zhang
Shupeng Huang
Mingzhen Wei
Yongmo Wu
Zhengyi Xie

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1634718

226 views

Review

Published on 25 Jun 2025

The role of probiotics, prebiotics, and postbiotics: cellular and molecular pathways activated on glial cells in Alzheimer’s disease

in Neurodegeneration

Aleidy Patricio-Martínez
Felipe Patricio
Edgar Macuil-Chapuli
Enoc Álvaro Martínez-Juárez
Steven Flores-Díaz
María Lilia Cedillo-Ramírez
Ilhuicamina Daniel Limón

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1598011

1,129 views

Editorial

Published on 20 Jun 2025

Editorial: Brain dysfunction in Gulf War illness: pathophysiology and treatment

in Neurodegeneration

Ashok K. Shetty
Kimberly Sullivan
Liang Qiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1642052

982 views

Brief Research Report

Accepted on 19 Jun 2025

GABAergic neurons are a key cell type in a Drosophila model of PARK14/PLA2G6-associated neurodegeneration Authors

in Neurodegeneration

Josefa Steinhauer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1534243

200 views

Correction

Published on 19 Jun 2025

Correction: Fingolimod inhibits inflammation but exacerbates brain edema in the acute phases of cerebral ischemia in diabetic mice

in Neurodegeneration

Wanlu Li
Tingting He
Lu Jiang
Rubing Shi
Yaying Song
Muyassar Mamtilahun
Yuanyuan Ma
Zhijun Zhang
Yaohui Tang
Guo-Yuan Yang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1639244

433 views

Original Research

Published on 19 Jun 2025

Interleukin-6-induced neuroinflammation is exacerbated by subclinical levels of interferon-α

in Neurodegeneration

Pattama Songkhunawej
Markus J. Hofer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1586400

699 views

Brief Research Report

Accepted on 18 Jun 2025

Targeting Oxidized Phosphatidylcholines in SOD1-Associated ALS: Therapeutic Potential of PC-OxPL-VecTab®

in Neurodegeneration

Andreia Gomes-Duarte
Sofia Pascoal
Rob Haselberg
Marina Sogorb
Sander van Deventer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1620181

164 views

Hypothesis and Theory

Published on 18 Jun 2025

Dominant twin peaks: a novel conjecture for the pathophysiologic basis of tremor frequency and fluctuation time in Parkinson’s disease

in Neurodegeneration

Furrukh Khan
David Novikov
Brian Dalm
Jessie Xiaoxi
Oliver Flouty
Evan Thomas

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1398834

498 views

Original Research

Published on 18 Jun 2025

The GLP-1 receptor agonist liraglutide inhibits necroptosis and neuroinflammation in a mouse model of Parkinson’s disease with diabetes co-morbidity

in Neurodegeneration

Xiaomin Zhang
Pengyang Du
Bo Bai
Peng Feng
Xia Lian
Christian Hölscher
Yongqing Wang
Guofang Xue

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1596506

846 views