Frontiers in Neuroscience | Neurodegeneration

Original Research

Published on 05 Sep 2025

Molecular pathogenesis of Alzheimer's disease onset in a mouse model: effects of cannabidiol treatment

in Neurodegeneration

Mary A. Bishara
Phoebe P. Chum
Fritz E. L. Miot
Ankita Hooda
Richard E. Hartman
Erik J. Behringer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1667585

297 views

Original Research

Accepted on 02 Sep 2025

Evaluating the Efficacy of Probiotics in Treating Parkinson's Disease Model Rats Using Magnetic Resonance Enhanced Gradient Echo T2-weighted Angiography Sequence

in Neurodegeneration

Yanmin Su
Yanchao Dong
Jingtao Feng
Xiaoxia Zhang
Ying Yu
Hongzhi Lu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1662530

270 views

Review

Published on 02 Sep 2025

Role of the mitochondrial regulatory factor CHCHD2 in neurodegenerative diseases

in Neurodegeneration

Xinyu Guo
Peiyu Xu
Chen Liang
Yuntao Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1639651

459 views

Original Research

Published on 01 Sep 2025

NETSseq reveals inflammatory and aging mechanisms in distinct cell types, driving cerebellar decline in ataxia telangiectasia

in Neurodegeneration

Giuliano G. Stirparo
Xiao Xu
Toni Thompson
Keith Page
Jenna R. M. Harvey
David Cadwalladr
Jason Lawrence
Russell J. Burley
Joel Juvvanapudi
Megan Roberts

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1636787

916 views

Original Research

Published on 29 Aug 2025

Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer’s disease

in Neurodegeneration

Oghenetega E. Imiruaye
Isis G. Perez
Brian C. Carson
Christian Crouzet
Jerome Garcia
Derick Han
Subhrajit Bhattacharya

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1649625

1,160 views

Correction

Published on 29 Aug 2025

Correction: Protective effects of Hif2 inhibitor PT-2385 on a neurological disorder induced by deficiency of Irp2

in Neurodegeneration

Jiaqi Shen
Li Xu
Yuxuan Li
Weichen Dong
Jing Cai
Yutong Liu
Hongting Zhao
Tianze Xu
Esther Meyron Holtz
Yanzhong Chang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1667076

530 views

Original Research

Published on 29 Aug 2025

Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease

in Neurodegeneration

Demos Kynigopoulos
Eleni Fella
Lucy Shahabian
Christiana C. Christodoulou
Revekka Papacharalampous
Konstantinos Diskos
Lida Evmorfia Vagiaki
Kyriaki Sidiropoulou
Menelaos Pipis
Kleopas A. Kleopa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1636624

1,421 views

Original Research

Accepted on 28 Aug 2025

The top 100 most cited publications on astrocytes in Alzheimer's disease from 2000 to 2025: A bibliometric analysis

in Neurodegeneration

Qi He
Hong Yu
Xinyao Zhou
Kangyi Yang
Wenjie Xiao
Zirui Gao
Qian He

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1593188

552 views

Original Research

Published on 28 Aug 2025

A high triglyceride-glucose index correlates with cognitive impairment in Parkinson’s disease: a cross-sectional study

in Neurodegeneration

Yongqing Cheng
Shuangfei You
Xin Wang
Yingchao Ge
Lei Li
Taojie Ren
Songjie Chen
Guojun He
Shouru Xue

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1620118

969 views

Mini Review

Accepted on 27 Aug 2025

Akkermansia muciniphila in Neurological Disorders: Mechanisms and Therapeutic Potential via the Gut-Brain Axis

in Neurodegeneration

Jingzhi Feng
Rizhao Pang
Xiaomin Hu
Jiancheng Liu
Wenchun Wang
Liuyi Chen
Anren Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1650807

280 views

Original Research

Published on 26 Aug 2025

Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study

in Neurodegeneration

Yejing Zhao
Xiang Wang
Jie Zhang
Yanyan Zhao
Yi Li
Ji Shen
Ying Yuan
Jing Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1663276

935 views

Systematic Review

Published on 25 Aug 2025

Emerging regenerative strategies for spinal cord injury: exosome-derived mechanisms and therapeutic insights

in Neurodegeneration

Haixia Fan
Jie Gao
Qian Chen
Shuangshuang Sun
Jinshen Guo
Xiaodong Liu
Jinhu Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1652196

1,402 views

Original Research

Published on 21 Aug 2025

A novel fluorescent probe, triphenylamine rhodamine-3-acetic acid (mRA) for the detection of Amyloid-β aggregates in Alzheimer's disease

in Neurodegeneration

Raja Chinnappan
Mateen A. Khan
Taj Mohammad
Sarah Mohammed Allwaibh
Shanmugam Easwaramoorthi
Ahmed Yaqinuddin
Sandhanasamy Devansan
Tanveer Ahmad Mir
Imtaiyaz Hassan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1653063

947 views

Methods

Published on 19 Aug 2025

DNA: detecting early signs of neurodegenerative diseases through activity and sleep analysis

in Neurodegeneration

Hasina Attaullah
Sanaullah Sanaullah
Annika Peters
Qazi Arbab Ahmed
Justin Baudisch
Thorsten Jungeblut

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1617758

969 views

Review

Published on 19 Aug 2025

Impacts of mitochondrial dysfunction on axonal microtubule bundles as a potential mechanism of neurodegeneration

in Neurodegeneration

Scott Murray-Cors
Milli Owens
Yu-Ting Liew
Maureece Day
William Cairns
Andreas Prokop

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1631752

1,494 views

Case Report

Published on 15 Aug 2025

Unusual presentation of neurobrucellosis presenting with the features of parkinsonism: two case reports and a review of the literature

in Neurodegeneration

Moneera Aldraihem
Thamer S. Alhowaish
Yazeed Alotaibi
Mohammed AlShareet
Abdulrahman A. Alrasheed
Mazen AlAmr
Omar A. Alsinaidi
Abdulrahman S. Ali
Hisham AlDhukair

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1647803

925 views