Frontiers in Neuroscience | Neurodegeneration

Original Research

Accepted on 15 Aug 2025

Spatiotemporal differential regulation of extrasynaptic GluN2B receptor subunits and PSA-NCAM in brain aging and Alzheimer's disease

in Neurodegeneration

Oghenetega Edward Imiruaye
Isis G Perez
Brian C Carson
Christian Crouzet
Jerome Garcia
Derick Han
Subhrajit Bhattacharya

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1649625

Case Report

Published on 15 Aug 2025

Unusual presentation of neurobrucellosis presenting with the features of parkinsonism: two case reports and a review of the literature

in Neurodegeneration

Moneera Aldraihem
Thamer S. Alhowaish
Yazeed Alotaibi
Mohammed AlShareet
Abdulrahman A. Alrasheed
Mazen AlAmr
Omar A. Alsinaidi
Abdulrahman S. Ali
Hisham AlDhukair

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1647803

364 views

Original Research

Accepted on 14 Aug 2025

Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer's disease

in Neurodegeneration

Demos Kynigopoulos
Eleni Fella
Lucy Shahabian
Christiana Christodoulou
Revekka Papacharalambous
Konstantinos Diskos
Lida Evmorfia Vagiaki
Kyriaki Sidiropoulou
Menelaos Pipis
Kleopas A Kleopa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1636624

158 views

Original Research

Accepted on 14 Aug 2025

A high triglyceride-glucose index correlates with cognitive impairment in Parkinson's disease：a cross-sectional study

in Neurodegeneration

Yongqing Cheng
Shuangfei You
Xin Wang
Yingchao Ge
Lei Li
Taojie Ren
Songjie Chen
Guojun He
Shouru Xue

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1620118

108 views

Original Research

Accepted on 13 Aug 2025

Plasma FGF2 and YAP1 as Novel Biomarkers for MCI in the Elderly: Analysis via Bioinformatics & Clinical Study

in Neurodegeneration

Yejing Zhao
Xiang Wang
Zhang Jie
Yanyan Zhao
Yi Li
Ji Shen
Ying Yuan
Jing Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1663276

206 views

Review

Published on 13 Aug 2025

Gut dysbiosis as a potential driver of Parkinson’s and Alzheimer’s disease pathogenesis

in Neurodegeneration

Jacob M. Pfaffinger
Kallie E. Hays
Jason Seeley
Priyadharshine Ramesh Babu
Rebecca Ryznar

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1600148

630 views

Systematic Review

Accepted on 11 Aug 2025

Emerging Regenerative Strategies for Spinal Cord Injury: Exosome-Derived Mechanisms and Therapeutic Insights

in Neurodegeneration

Haixia Fan
Jie Gao
Qian Chen
Shuangshuang Sun
Jinshen Guo
Liu Xiaodong
Jinhu Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1652196

273 views

Original Research

Accepted on 11 Aug 2025

Molecular Pathogenesis of Alzheimer's Disease Onset in a Mouse Model: Effects of Cannabidiol Treatment

in Neurodegeneration

Mary A Bishara
Phoebe P Chum
Fritz E L Miot
Ankita Hooda
RIchard E Hartman
Erik J Behringer

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1667585

156 views

Original Research

Published on 11 Aug 2025

Brain functional network abnormalities in Parkinson’s disease patients at different disease stages

in Neurodegeneration

Wei Wei
Xinhui Wang
Chao Han
Yu Shen
Panlong Li
Yan Bai
Shuo Liu
Jingyao Xu
Yanhong Shi
Zhou Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1627838

416 views

Correction

Accepted on 07 Aug 2025

Correction: Protective Effects of Hif2 Inhibitor PT-2385 on a Neurological DisorderInduced by Deficiency of Irp2

in Neurodegeneration

Jiaqi Shen
Li Xu
Yuxuan Li
Weichen Dong
Jing Cai
Yutong Liu
Hongting Zhao
Tianze Xu
Esther G. Meyron-Holtz
Yanzhong Chang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1667076

117 views

Original Research

Published on 06 Aug 2025

Disrupted theta oscillation propagation in healthy elderly individuals with apolipoprotein E epsilon 4 allele

in Neurodegeneration

Duho Sihn
Min-Ki Kim
Sung-Phil Kim

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1579329

472 views

Review

Published on 01 Aug 2025

The emerging role of cellular senescence in amyotrophic lateral sclerosis

in Neurodegeneration

Xingli Tan
Naiyong Gao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1599492

856 views

Correction

Published on 01 Aug 2025

Correction: Nicotine-mediated effects in neuronal and mouse models of synucleinopathy

in Neurodegeneration

Mohamed Bilal Fares
Omar Alijevic
Stephanie Johne
Cassia Overk
Makoto Hashimoto
Athanasios Kondylis
Anthony Adame
Remi Dulize
Dariusz Peric
Catherine Nury

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1662162

585 views

Original Research

Accepted on 31 Jul 2025

A Novel Fluorescent Probe Triphenylamine Rhodamine-3-Acetic Acid (mRA) for the Detection of Amyloid-β Aggregates in Alzheimer's Disease

in Neurodegeneration

Raja Chinnappan
Mateen A. Khan
Taj Mohammad
Sarah Mohammed Allwaibh
Shanmugam Easwaramoorthi
Ahmed Yaqinuddin
Sandhanasamy Devansan
Ahmad Mir
Imtaiyaz Hassan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1653063

222 views

Correction

Published on 29 Jul 2025

Correction: Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice

in Neurodegeneration

Zhongwu Su
Yuyan Chen
Yu Liu
Jinyuan Cao
Jie Cui
Haitong Chen
Qi Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1640349

517 views

Original Research

Published on 23 Jul 2025

Accumulation of TDP-43 causes karyopherin-α4 pathology that characterises amyotrophic lateral sclerosis

in Neurodegeneration

Manpreet Singh Atwal
Jerneja Nimac
Urša Čerček
Sarah Ricarda Goesch
Hannah Rebecca Goesch
Paraskevi Tziortzouda
Tiziana Ercolani
Anna Zatorska
Terouz Pasha
Ivo Carre

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1558227

1,658 views