Frontiers in Neuroscience | Neurodegeneration

Review

Published on 12 May 2025

Biological engineering approaches for modulating the pathological microenvironment and promoting axonal regeneration after spinal cord injury

in Neurodegeneration

Xiaohong Chen
Rong Huang
Zhe Yang
Jun Zhang
Yanling Yang
Feng Gao
Minli Liu
Shengjun Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1574763

173 views

Review

Published on 12 May 2025

The key role of the ferroptosis mechanism in neurological diseases and prospects for targeted therapy

in Neurodegeneration

Chenyu Xie
Nan Wu
Jiaojiao Guo
Liangliang Ma
Congcong Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1591417

142 views

Opinion

Accepted on 08 May 2025

Fool's gold standard? Immunoperoxidase staining with the mouse monoclonal antibody (Clone 22C11) for detecting axonal pathology after traumatic brain injury

in Neurodegeneration

Guoxiang Xiong
Shanti Rao Tummala
Akiva S Cohen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1613172

Review

Accepted on 08 May 2025

Brain Organoid Model Systems of Neurodegenerative Diseases: Recent Progress and Future Prospects

in Neurodegeneration

Saniyah Shaikh
Luqman Siddique
Hafsah T Khalifey
Rutaba Mahereen
Thaabit Raziq
Rushdan M Firdous
Aisha Siddique
Ismail M Shakir
Zara Ahmed
Arshiya Akbar

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1604435

Review

Published on 08 May 2025

Significance of gene therapy in neurodegenerative diseases

in Neurodegeneration

Lingling Wang
Lin Ma
Zihan Gao
Ying Wang
Jiaoxue Qiu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1515255

763 views

Editorial

Published on 08 May 2025

Editorial: Olfactory dysfunction in neurodegenerative diseases

in Neurodegeneration

Debanjan Dasgupta
Thomas Heinbockel
Swagata Ghatak

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1611870

609 views

Brief Research Report

Accepted on 07 May 2025

APOE genetic variability in an Egyptian cohort of PD

in Neurodegeneration

Eman M Khedr
Martina B William
Aliaa El-Hosseiny
Ali Soliman Shalash
Gharib Fawi
Mohamed H. Yousef
Shaimaa Ibrahim El-Jaafary
Hamin Lee
Alina Jama
Mohamed Koraym

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1579968

Original Research

Accepted on 07 May 2025

Bidirectional Modulation of Alzheimer's Disease via Gut Microbiota: Rescue by Fecal Transplantation from Healthy Donors and Aggravation by Colitis-Associated Dysbiosis

in Neurodegeneration

Chenglong Zhou
Xin Feng
Huina Liu
Ting Cai
Yihong Li
Huadong Fan

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1593854

Review

Published on 07 May 2025

The roles of microglia and astrocytes in neuroinflammation of Alzheimer’s disease

in Neurodegeneration

Jialin Han
Zhi Zhang
Pengfei Zhang
Qian Yu
Qian Cheng
Zhiming Lu
Shuai Zong

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1575453

502 views

Original Research

Published on 07 May 2025

TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease

in Neurodegeneration

Sarah M. Carpanini
Barry M. Bradford
Alessio Alfieri
Pedro Piccardo
Jimena Monzón-Sandoval
Deborah Brown
Aileen Boyle
Aleksandra Pokrovskaya
Neil A. Mabbott
Jean Manson

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1525017

599 views

Original Research

Accepted on 06 May 2025

Expression and potential regulatory mechanism of cellular senescencerelated genes in Alzheimer's disease based on single-cell and bulk RNA datasets

in Neurodegeneration

Dujuan Sha
Jingxuan Zhang
Xu Fang
Xinyu Wang
Xuan He
Shu Xin

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1595847

Original Research

Published on 06 May 2025

NFκB1: a common biomarker linking Alzheimer's and Parkinson's disease pathology

in Neurodegeneration

Adam Cunningham
Emma Barrett
Sebastian Risch
Peter H. U. Lee
Chan Lee
Abhay Moghekar
Prabir Patra
Joon W. Shim

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1589857

868 views

Original Research

Published on 29 Apr 2025

Peak alpha frequency and alpha power spectral density as vulnerability markers of cognitive impairment in Parkinson’s disease: an exploratory EEG study

in Neurodegeneration

Yuqing Zhao
Jiayu Cai
Jian Song
Haoran Shi
Weicheng Kong
Xinlei Li
Wei Wei
Xiehua Xue

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1575815

538 views

Review

Published on 29 Apr 2025

Comparative analysis of neuroinflammatory pathways in Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis: insights into similarities and distinctions

in Neurodegeneration

Julia Doroszkiewicz
Izabela Winkel
Barbara Mroczko

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1579511

534 views

Original Research

Accepted on 28 Apr 2025

Improved Dementia Screening for Elderly with Low Education in South Korea Using the Cognitive Impairment Screening Test (CIST)

in Neurodegeneration

Kyung Wook Kang
Gilsoon Park
Hyunsoo Kim
Soo Hyun Cho
Seong-Min Choi
Kang-Ho Choi
Hak-Loh Lee
Gwangsoon Shon
Byeong Chae Kim
Hosung Kim

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1599019

176 views

Original Research

Accepted on 28 Apr 2025

Differential retinal ganglion cell resilience to optic nerve injury across vertebrate species

in Neurodegeneration

Julie D De Schutter
Anyi Zhang
Pieter-Jan Serneels
Lieve Moons
Luca Masin
Steven Bergmans

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1596464

130 views