In the original article, there was a mistake in the legend for Figure 2 and Figure 3 as published. The scale bars of Figures 2E, F, G, 3A, B were inaccurately described. The correct legends appear below.
Figure 2
Figure 3
In the original article, there was a mistake in Figure 2G as published. We found that OE2 in Figure 2G was improperly placed during the figure editing process. The corrected Figure 2 appears below.
In the original article, there was a mistake in Figure 5I as published. DAPI of MCF7 scramble p-AKT was wrongly placed. The corrected Figure 5 appears below.
Figure 5
In the original article, there was a mistake in Table 2 as published. In the process of statistical analysis, the statistical module of SPSS was wrongly selected. The corrected Table 2 appears below.
Table 2
| Variables | DFS | |||
|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | 1.073 (0.751-1.533) | 0.699 | 1.261 (0.847-1.878) | 0.254 |
| Menopausal status | 0.603 (0.423-0.860) | 0.005 | 0.123 (0.025-0.615) | 0.011 |
| T stage | 1.117 (0.771-1.619) | 0.557 | 1.142 (0.674-1.934) | 0.621 |
| N stage | 0.974 (0.669-1.417) | 0.890 | 0.951 (0.525-1.723) | 0.869 |
| TNM stage | 0.745 (0.472-1.175) | 0.206 | 0.806 (0.466-1.395) | 0.442 |
| Pathological type | 0.864 (0.602-1.239) | 0.427 | 0.953 (0.551-1.650) | 0.864 |
| Histological grade | 0.911 (0.588-1.412) | 0.677 | 0.837 (0.473-1.480) | 0.540 |
| ER status | 0.712 (0.472-1.077) | 0.107 | 0.812 (0.488-1.352) | 0.424 |
| PR status | 0.730 (0.491-1.086) | 0.120 | 0.759 (0.468-1.231) | 0.264 |
| HER-2 status | 1.593(0.912-2.781) | 0.102 | 1.727 (0.961-3.102) | 0.068 |
| Ki-67 status | 0.871 (0.585-1.295) | 0.495 | 0.797 (0.497-1.279) | 0.347 |
| Molecular subtype | 0.802 (0.380-1.695) | 0.564 | 0.932 (0.431-2.016) | 0.858 |
| GLYAT status | 1.565 (1.098-2.232) | 0.013 | 0.145 (0.031-0.690) | 0.015 |
Univariate and multivariate analyses of clinicopathological risk factors for disease-free survival among breast cancer patients.
In the original article, there was an error in the results of multivariate analysis as the statistical module of SPSS was wrongly selected. A correction has been made to Results, “Lower GLYAT Expression Is Correlated With Poorer Prognosis and Malignant Clinicopathological Features in Human Breast Cancer Tissues”, paragraph 3:
“BC patients were analyzed for their GLYAT status and prognosis via Kaplan-Meier survival analysis as well as log-rank tests after being followed up for an average of 61.75 months (range, 9–77 months). We found that those with decreased GLYAT levels experienced poorer disease-free survival (DFS) (Figure 6D; P=0.012). GLYAT expression was a significant indicator of DFS rates in breast cancer patients based on univariate Cox regression analysis, demonstrating a hazard ratio (HR) of 1.565 [P<0.05; 95% confidence interval (CI) 1.098-2.232] (Table 2). Further multivariate analysis revealed that GLYAT expression was significantly related to DFS (HR, 0.145; 95% CI, 0.031-0.690; P=0.015) (Table 2) and represented an independent risk factor of prognosis for BC”.
After rediscussing the author contributions, all the authors agree to change the former co-responding author to co-author. The corrected Author Contributions Statement appears below.
The authors apologize for these errors and state that these do not change the scientific conclusions of the article in any way. The original article has been updated.
Publisher’s Note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.
Statements
Author contributions
SG conceived and designed the experiments as well as contributed to the writing of the manuscript. XT, NW, MJ, YZ, NM, and RW performed the experiments. GL provided the tumor tissue microarray and brief guidance about conception at the beginning of the study. XT performed clinical analysis and helped with drawing the figures. SG revised the paper. All authors contributed to the article and approved the submitted version.
Summary
Keywords
GLYAT, breast cancer, EMT, PI3K/AKT, clinicopathological features, prognosis
Citation
Tian X, Wu L, Jiang M, Zhang Z, Wu R, Miao J, Liu C and Gao S (2022) Corrigendum: Downregulation of GLYAT Facilitates Tumor Growth and Metastasis and Poor Clinical Outcomes Through the PI3K/AKT/Snail Pathway in Human Breast Cancer. Front. Oncol. 12:793448. doi: 10.3389/fonc.2022.793448
Received
12 October 2021
Accepted
04 March 2022
Published
06 April 2022
Volume
12 - 2022
Edited and reviewed by
Zhijie Jason Liu, The University of Texas Health Science Center, United States
Updates
Copyright
© 2022 Tian, Wu, Jiang, Zhang, Wu, Miao, Liu and Gao.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Song Gao, gaogao0229@hotmail.com
This article was submitted to Women's Cancer, a section of the journal Frontiers in Oncology
Disclaimer
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.