CASE REPORT article
Front. Oncol.
Sec. Radiation Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1320679
This article is part of the Research TopicCase Reports in Radiation Oncology: 2025View all 16 articles
Radical radiation therapy for esophageal carcinoma in situs inversus totalis (SIT) with the history of surgery for lung cancer: a case report
Provisionally accepted
- Jinhua Central Hospital, Jinhua, China
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Situs inversus totalis (SIT) is a rare congenital anatomical variation. This case report describes the first instance of a patient with both lung and esophageal cancer along with SIT. Additionally, it presents the first successful radical radiation therapy for esophageal carcinoma with SIT. The patient underwent a left upper lobectomy with lymph node dissection using video-assisted thoracic surgery (VATS) for lung cancer in 2021 and radical radiotherapy for esophageal cancer in 2023.
Keywords: Situs inversus totalis, Radical radiation therapy, Esophageal carcinoma, Lung carcinoma, Multiple primary malignancies
Received: 12 Oct 2023; Accepted: 22 Aug 2025.
Copyright: © 2025 Chen, Xu, Xu, Li, Ma and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Shubo Ding, Jinhua Central Hospital, Jinhua, China
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