SYSTEMATIC REVIEW article
Front. Oncol.
Sec. Radiation Oncology
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1465104
Global research trends in radiotherapy for bone metastases: a systematic bibliometric analysis
Provisionally accepted
- Beijing Luhe Hospital, Capital Medical University, Beijing, China
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Background: With the development of various advanced radiotherapy techniques, research related to radiotherapy for bone metastases has made great progress, and scholars have published a large number of publications. In this study, we summarized the knowledge structure of radiotherapy for bone metastases and outlined the research hotspots through bibliometric analysis. Methods:Publications on radiotherapy for bone metastases from 1992 to 2024 were searched in the Web of Science Core Collection (WoSCC) database. Countries, institutions, authors, references, and keywords in the field were visualized using VOSviewer version 1.6.19 and CiteSpace version 6.3.R1. Results: 1303 publications from 71 countries were included in this study. The number of research publications on radiotherapy for bone metastases has been increasing year by year. The United States of America (USA) ranking first in terms of publication count and co-citation frequency. The most prolific institutions and authors were the University of Toronto and Sahgal A, while Chow E was the most co-cited author. The most co-cited paper was published by Lutz S et al. in 2011 in Internation Journal Of RadiationOncology Physics. "stereotactic body radiotherapy", "spine metastases", "spinal cord compression", " immunotherapy" and "oligometastases" are the main keywords of the current research topics.The application of stereotactic body radiotherapy (SBRT) in the treatment of patients with bone metastases, especially oligometastases, has attracted extensive attention from researchers. How to choose reasonable radiotherapy for patients with complicated bone metastases has now become a research hotspot.Radiotherapy combined with immunotherapy may be the future development trend.
Keywords: Radiotherapy, Bone Metastases, bibliometric analysis, Citespace, VOSviewer
Received: 19 Sep 2024; Accepted: 11 Aug 2025.
Copyright: © 2025 Yin, Liu, Nan, Zheng, Shi, Yuan, Qiteng and Gao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yuyan Gao, Beijing Luhe Hospital, Capital Medical University, Beijing, China
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