CASE REPORT article
Front. Oncol.
Sec. Breast Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1580441
Metastasis of prostate cancer to breast: A Case Report
Provisionally accepted
Sirui Zhang1
Wenting Peng2
Lin Cheng2Bei Pei2Xiaoli Zhou2Mengjie Wang2Ling Jiang1Chao Lu2*Lingyun Xu2*- 1Nanjing Medical University, Nanjing, China
- 2Changzhou No.2 People's Hospital, Changzhou, Jiangsu Province, China
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We describe a 68-year-old man who had prostate cancer (PCa) diagnosed with breast metastasis, presenting as a breast mass. Seven years ago, the patient had PCa with bone metastasis and had been systematically receiving endocrine therapy for prostate cancer and osteoprotective treatment since the diagnosis. In October 2023, the patient visited our hospital due to bilateral breast masses for four days. Enlarged supraclavicular lymph nodes were detected, while multiple solid space-occupying lesions were observed in bilateral mammary tissues, classified as Breast imaging reporting and data system (BI-RADS) 4C. Subsequently, he underwent lumpectomy and was diagnosed with metastatic prostatic acinar adenocarcinoma.
Keywords: prostate cancer, breast metastasis, Male breast cancer, BRCA mutations, androgen receptor, Differential diagnosis. Extramammary malignancies Prostate cancer, differential diagnosis
Received: 20 Feb 2025; Accepted: 28 Apr 2025.
Copyright: © 2025 Zhang, Peng, Cheng, Pei, Zhou, Wang, Jiang, Lu and Xu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Chao Lu, Changzhou No.2 People's Hospital, Changzhou, Jiangsu Province, China
Lingyun Xu, Changzhou No.2 People's Hospital, Changzhou, Jiangsu Province, China
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