CASE REPORT article
Front. Oncol.
Sec. Hematologic Malignancies
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1583504
Management of multiple primary prostate malignant tumors: Case report of synchronous Prostatic adenocarcinoma and lymphoma
Provisionally accepted
- 1The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China
- 2Fujian Medical University, Fuzhou, China
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The occurrence of multiple primary prostate cancer is extremely rare and there is no consensus on its diagnosis and treatment. This article presents an elderly male patient with both acinar adenocarcinoma of the prostate and small lymphocytic lymphoma ( SLL ) invading the prostate. He was treated with ibrutinib for the lymphoma and goserelin and bicalutamide for the prostate cancer, resulting in control of both conditions. The patient's case and literature review highlight the importance of multiple-site biopsy for diagnosis and need for multidisciplinary collaboration. Treatment plans should take into account disease severity and potential drug interactions to optimise therapeutic outcomes while minimising adverse effects.
Keywords: Multiple primary prostate cancer, tumor heterogeneity, Treatment, case report, CLL - chronic lymphoblastic leukemia, TP53
Received: 26 Feb 2025; Accepted: 27 May 2025.
Copyright: © 2025 Zhuang, Wang, Wu, Cai and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Wanyi Liu, Fujian Medical University, Fuzhou, China
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