REVIEW article
Front. Oncol.
Sec. Cancer Metabolism
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1604227
Regulation of Sphingolipid Metabolism in the Immune Microenvironment of Gastric Cancer: Current Insights and Future Directions
Provisionally accepted
- 1Baotou Cancer Hospital, Baotou, China
- 2Baotou Medical College, Baotou, China
- 3First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, China
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In recent years, the role of sphingolipid metabolism in the tumor immune microenvironment has gradually gained attention, particularly in gastric cancer research. Sphingolipids are crucial components of cell membranes that regulate cell signaling and immune responses, making them important in tumor biology research.Despite numerous studies exploring the relationship between sphingolipid metabolism and gastric cancer, the specific regulatory mechanisms remain unclear. Further investigation is needed to understand their roles in the immune microenvironment.
Keywords: Sphingolipid metabolism, gastric cancer, immune microenvironment, Regulatory role, Mechanistic research
Received: 01 Apr 2025; Accepted: 14 Jul 2025.
Copyright: © 2025 Hua, Zhang, Liu, Tian, Zhang, Song, Tian and Yin. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Qinggang Tian, Baotou Cancer Hospital, Baotou, China
Fangrui Yin, First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, China
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