- 1Department of Medical Oncology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
- 2Department of Cirrhosis, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
- 3Endoscopic Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
A Corrigendum on
Canmei formula reduces colitis-associated colorectal carcinogenesis in mice by modulating the composition of gut microbiota
by Zhang H, Hui D, Li Y, Xiong G and Fu X (2019). Front. Oncol. 9:1149. doi: 10.3389/fonc.2019.01149
In the published article, there was three errors in “H&E stains of serial sections of colons” of Figure 2G as published. There are three errors in the original version of Figure 2G, which are as follows:
The first error is that the pathology pictures of the MC group (°C200, blue border in Figure 2G-Original Version) and the NC group (°C400, red border in Figure 2G-Original Version) are the HE staining results of the CMF-A group (°C200, °C400). The second error is that the picture in the NC group (°C200, green border in Figure 2G-Original Version) should be the staining results of the MC group (°C200).The third error is that the HE staining results of the NC group (°C200 in Figure 2G-Original Version) are missing.
The corrected pathology pictures “H&E stains of serial sections of colons” of Figure 2G in the correct version and its caption “CMF treatment reduced the incidence of CRA in mice. C57BL/6 mice were subjected to an AOM-based CRC induction protocol using three cycles of 2.5% DSS in drinking water. (A) Diagram shows the experimental course of AOM/DSS mouse model. (B) Body weights of AOM/DSS group and AOM/DSS + CMF group (1, 3, 4, 5, 6). (C) Histogram showing the size distribution of tumors. (D–F) Tumor sizes in different parts determined by Spot software for microscopic tumors or a caliper for macroscopic tumors. Average tumor size ± S.D. is shown; (G) H&E stains of serial sections of colons. *P < 0.05; **P < 0.01. Data are presented as mean ± SD of mice in each group” appear below.

Figure 2. CMF treatment reduced the incidence of CRA in mice. C57BL/6 mice were subjected to an AOM-based CRC induction protocol using three cycles of 2.5% DSS in drinking water. (A) Diagram shows the experimental course of AOM/DSS mouse model. (B) Body weights of AOM/DSS group and AOM/DSS + CMF group (1, 3, 4, 5, 6). (C) Histogram showing the size distribution of tumors. (D–F) Tumor sizes in different parts determined by Spot software for microscopic tumors or a caliper for macroscopic tumors. Average tumor size ± S.D. is shown; (G) H&E stains of serial sections of colons. *P < 0.05; **P < 0.01. Data are presented as mean ± SD of mice in each group
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: Canmei formula (CMF), traditional Chinese medicine, gut microbiota, AOM/DSS, colorectal carcinogenesis
Citation: Zhang H, Hui D, Li Y, Xiong G and Fu X (2025) Corrigendum: Canmei formula reduces colitis-associated colorectal carcinogenesis in mice by modulating the composition of gut microbiota. Front. Oncol. 15:1609683. doi: 10.3389/fonc.2025.1609683
Received: 10 April 2025; Accepted: 17 April 2025;
Published: 12 May 2025.
Edited and Reviewed by:
Dong-Hua Yang, New York College of Traditional Chinese Medicine, United StatesCopyright © 2025 Zhang, Hui, Li, Xiong and Fu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xiaoling Fu, ZnV4aWFvbGluZzExMUAxNjMuY29t; Guangsu Xiong, eGlvbmdndWFuZ3N1QHNoeXVleWFuZ2hvc3BpdGFsLmNvbQ==
†These authors have contributed equally to this work