CASE REPORT article
Front. Oncol.
Sec. Head and Neck Cancer
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1611107
This article is part of the Research TopicPathophysiology and Therapeutic Strategies for Oral and Head and Neck CancersView all 16 articles
Long-term Survival of Subglottic Adenoid Cystic Carcinoma: A Case Report
Provisionally accepted
- Hubei Cancer Hospital, Wuhan, China
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Adenoid cystic carcinoma of the larynx is rare, mainly localizing in the subglottic region. The clinical presentation is predominantly characterized by dyspnea and hoarseness. In this study, a 38-year-old woman presented symptoms that included hoarseness, wheezing, and coughing. A diagnosis of subglottic adenoid cystic carcinoma was made by laryngoscopy and biopsy and a total laryngectomy was subsequently performed. A decade after the initial surgical intervention, the tumor recurred in the local region. Consequently, a subsequent surgical procedure was undertaken, accompanied by postoperative radiotherapy. A subsequent 5-year follow-up examination revealed no evidence of local recurrence or distant metastasis. Subglottic adenoid cystic carcinoma is an uncommon malignancy. A comprehensive surgical excision can yield a favorable therapeutic outcome. In cases of recurrence, subsequent surgical intervention and postoperative supplemental radiotherapy can achieve positive results.
Keywords: Adenoid cystic carcinoma, Surgery, Recurrence, Radiotherapy, case report
Received: 13 Apr 2025; Accepted: 07 Jul 2025.
Copyright: © 2025 Yin and Gui. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Chao Gui, Hubei Cancer Hospital, Wuhan, China
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