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CORRECTION article

Front. Oncol., 21 July 2025

Sec. Molecular and Cellular Oncology

Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1641207

Correction: Over-expression of long non-coding RNA-AC099850.3 correlates with tumor progression and poor prognosis in lung adenocarcinoma

Xi Chen&#x;Xi Chen1†Jishu Guo&#x;Jishu Guo2†Fan Zhou&#x;Fan Zhou3†Wenjun Ren&#x;Wenjun Ren4†Jun Pu*Jun Pu1*Luciano Mutti*Luciano Mutti5*Xiaoqun Niu*Xiaoqun Niu6*Xiulin Jiang*Xiulin Jiang7*
  • 1Department of Neurosurgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China
  • 2Institute for Ecological Research and Pollution Control of Plateau Lakes, School of Ecology and Environmental Science, Yunnan University, Kunming, China
  • 3Hematology and Rheumatology Department, The Pu’er People’s Hospital, Pu’er, China
  • 4Department of Cardiovascular Surgery, The First People’s Hospital of Yunnan Province, Kunming, China
  • 5Sbarro Institute for Cancer Research and Molecular Medicine, Center for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA, United States
  • 6Department of Respiratory Medicine, Second Hospital of Kunming Medical University, Kunming, China
  • 7Kunming College of Life Science, University of Chinese Academy of Sciences, Beijing, China

A Correction on
Over-expression of long non-coding RNA-AC099850.3 correlates with tumor progression and poor prognosis in lung adenocarcinoma

By Chen X, Guo J, Zhou F, Ren W, Pu J, Mutti L, Niu X and Jiang X (2022) Front. Oncol. 12:895708. doi: 10.3389/fonc.2022.895708

Error in Figure

In the published article, there was an error in Figure 11G as published. The representative picture of BRDU, H1975 cells was presented incorrectly. This occurred primarily because there were too many pictures taken with the microscope on the disc. Confusing duplicate document numbers led us to upload the wrong image. The corrected Figure 11G appears below.

Figure 11
Graphs and images depict the effect of siRNA on AC009850.3 expression and cell proliferation. Panels A to C show decreased expression in siRNA-treated A549 and H1975 cells compared to controls. Panels D and E display cell viability over time, indicating reduced proliferation with siRNA. Panels F and G illustrate BrdU incorporation assays, showing lower proliferation rates in treated cells. Panels H and I present cell migration assays, highlighting fewer migrating cells with siRNA treatment. Statistical significance is indicated with asterisks.

Figure 11. lncRNA-AC099850.3 modulates LUAD cell proliferation and migration in vitro. (A) The relative expression level of AC099850.3 in lung adenocarcinoma cancerous cell lines, including H358, H1975 and A549 examined by Real-time RT-PCR, compared to normal human bronchial epithelial cell line: BEAS-2B. (B, C) Establishment of AC099850.3 knockdown cell lines in A549 and H1975 verified by Real-time RT-PCR (D–G) Knockdown of lncRNA AC099850.3 significantly inhibits cell proliferation as measured by CCK8 and BrdU assay. (H, I) knockdown of lncRNA AC099850.3 dramatically inhibits LUAD cells migration ability examined by transwell assay. ***P < 0.001. NC, Negative control; siRNA, AC099850.3 siRNA.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: lncRNA, lung adenocarcinoma, prognosis biomarker, immune infiltration, ceRNA, cell proliferation, cell migration

Citation: Chen X, Guo J, Zhou F, Ren W, Pu J, Mutti L, Niu X and Jiang X (2025) Correction: Over-expression of long non-coding RNA-AC099850.3 correlates with tumor progression and poor prognosis in lung adenocarcinoma. Front. Oncol. 15:1641207. doi: 10.3389/fonc.2025.1641207

Received: 04 June 2025; Accepted: 04 July 2025;
Published: 21 July 2025.

Edited and Reviewed by:

Sharon R Pine, University of Colorado Anschutz Medical Campus, United States

Copyright © 2025 Chen, Guo, Zhou, Ren, Pu, Mutti, Niu and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Xiulin Jiang, amlhbmd4aXVsaW5AbWFpbC5raXouYWMuY24=; Xiaoqun Niu, NjczNDA5MjU2QHFxLmNvbQ==; Luciano Mutti, bHVjaWFuby5tdXR0aUB0ZW1wbGUuZWR1; Jun Pu, cHVqdW4zMDNAYWxpeXVuLmNvbQ==

These authors have contributed equally to this work

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.