CASE REPORT article
Front. Oncol.
Sec. Breast Cancer
A Case Report of Multiple Primary Malignant Tumors: Breast Cancer and Colorectal Cancer
Provisionally accepted
Mirinisa Kaicaier
Shengjie Liu
Yuhan ZhangXueping HouYuying WangAisaide AikelaimuLiyuan MaWeihua Jiang*- 新疆医科大学附属肿瘤医院, 乌鲁木齐, China
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Breast cancer and colorectal cancer are both common malignant tumors worldwide. This report describes a case of multiple primary malignant tumors (MPMT) in a 52-year-old female patient diagnosed successively with right breast triple-negative breast cancer (T2N1M0, stage IIb) and rectal moderately differentiated adenocarcinoma (pT3N0M0, stage IIa). Through a multidisciplinary team (MDT) approach, we developed a treatment strategy involving breast-conserving surgery for the breast cancer followed by laparoscopic radical resection for the rectal cancer. Postoperative sequential therapy comprised TP chemotherapy (albumin-bound paclitaxel plus carboplatin), radiotherapy, and capecitabine. The patient developed Grade IV bone marrow suppression during chemotherapy, which improved after aggressive supportive care. The patient is currently in disease remission. This case highlights the importance of multidisciplinary collaboration, genetic risk assessment, individualized treatment decisions, comprehensive tumor management, and robust supportive care in the diagnosis and treatment of multiple primary malignant tumors , providing valuable insights for managing similar clinical cases.
Keywords: breast cancer, colorectal cancer, Multiple primary malignant tumors, Multidisciplinary team, chemotherapy, adverse reaction
Received: 25 Sep 2025; Accepted: 13 Nov 2025.
Copyright: © 2025 Kaicaier, Liu, Zhang, Hou, Wang, Aikelaimu, Ma and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Weihua Jiang, jsh610@163.com
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