CORRECTION article
Front. Oncol.
Sec. Pharmacology of Anti-Cancer Drugs
This article is part of the Research TopicExosomes in Renal Cell Cancer: A New Era in Diagnosis and TreatmentView all 3 articles
Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle
Provisionally accepted
- 1Department of Education, Shandong Provincial Hospital, Jinan, China
- 2Zaozhuang Municipal Hospital, Zaozhuang, China
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"Construction and evaluation of therapeutic results in a mouse RCC model. Part (A) describes the construction process of the mouse RCC model. First, the cells were digested with trypsin, and appropriate amounts of mouse RCC Renca cells were collected. Then, these cells were injected subcutaneously into the axilla of the mice. After more than one week, the formation of xenografts was observed in the axilla of the mice. When the RCC xenograft volumes of mice in each experimental group were similar, treatment was initiated. Part (B) shows the RCC xenograft samples isolated from mice in each group after 14 days of treatment. Among them, ① represents the RCC xenograft samples of mice in group A, ② represents those in group B, and ③ represents those in group C. This figure was previously presented in the author's (Shengyou Song) unpublished postgraduate dissertation. Part (C) shows the analysis of hematoxylin-eosin (HE) pathological staining of RCC xenograft tumors in each group of mice. Part (D) presents the growth curves of RCC xenografts in each group of mice to evaluate the growth dynamics of the cancers. Part (E) shows the weight changes of the mice in each group during the experiment. A difference was considered statistically significant if P < 0.05, *P < 0.05, **P < 0.01, or ***P < 0.001; alternatively, a difference is considered not significant (ns) if P > 0.05."
Keywords: Lathyrol, renal cell cancer, TGF-β/Smad signaling pathway, Cell Cycle, proliferation
Received: 15 Oct 2025; Accepted: 04 Nov 2025.
Copyright: © 2025 Song and Song. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yalin Song, songyalin095@gmail.com
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