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CORRECTION article

Front. Oncol., 03 December 2025

Sec. Thoracic Oncology

Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1726889

Correction: Perilesional edema diameter associated with brain metastases as a predictive factor of response to radiotherapy in non-small cell lung cancer

This article is a correction to:

  1. Perilesional edema diameter associated with brain metastases as a predictive factor of response to radiotherapy in non-small cell lung cancer

    1. Read original article
Oscar Arrieta*&#x;Oscar Arrieta1*†Laura Margarita Bolao-GuerraLaura Margarita Bolaño-Guerra1Enrique Caball-Prez&#x;Enrique Caballé-Pérez1†Luis Lara-Mejía&#x;Luis Lara-Mejía1†Jenny G. TurcottJenny G. Turcott1Salvador GutirrezSalvador Gutiérrez1Francisco Lozano-RuizFrancisco Lozano-Ruiz2Luis Cabrera-MirandaLuis Cabrera-Miranda1Andrs Mauricio Arroyave-RamírezAndrés Mauricio Arroyave-Ramírez3Federico Maldonado-MagosFederico Maldonado-Magos4Luis CorralesLuis Corrales5Claudio MartínClaudio Martín6Ana Pamela Gmez-García&#x;Ana Pamela Gómez-García1†Bernardo Cacho-DíazBernardo Cacho-Díaz7Andrs F. CardonaAndrés F. Cardona8
  • 1Thoracic Oncology Unit, Department of Thoracic Oncology, Instituto Nacional de Cancerología (INCan), México City, Mexico
  • 2Radioncology Department, Hospital Medica Sur, México City, Mexico
  • 3Medical Oncology Department, Hospital Medica Sur, México City, Mexico
  • 4Radiotherapy Unit, Instituto Nacional de Cancerología (INCan), México City, Mexico
  • 5Oncology Department, Hospital San Juan de Dios, San José, Costa Rica
  • 6Thoracic Oncology Unit, Alexander Fleming Institute, Buenos Aires, Argentina
  • 7Neuro-oncology Unit, Instituto Nacional de Cancerología (INCan), México City, Mexico
  • 8Direction of Research and Education, Luis Carlos Sarmiento Angulo Cancer Treatment and Research Center - Cancer Treatment and Research Cente (CTIC), Bogotá, Colombia

A Correction on
Perilesional edema diameter associated with brain metastases as a predictive factor of response to radiotherapy in non-small cell lung cancer

By Arrieta O, Bolaño-Guerra LM, Caballé-Pérez E, Lara-Mejía L, Turcott JG, Gutiérrez S, Lozano-Ruiz F, Cabrera-Miranda L, Arroyave-Ramírez AM, Maldonado-Magos F, Corrales L, Martín C, Gómez-García AP, Cacho-Díaz B and Cardona AF (2023) Front. Oncol. 13:1251620. doi: 10.3389/fonc.2023.1251620

There was a mistake in Figure 3B and Figure 3C, as published. Kaplan-Meier curves were plotted without censored events. The corrected Figure 3B and Figure 3C, appear below.

Figure 3
Panel A shows a waterfall plot indicating the percentage change from baseline for patients sorted by maximum decrease, categorized by PED size. Panels B and C display Kaplan-Meier survival curves. Panel B shows intracranial progression-free survival, while panel C illustrates overall survival, both comparing PED sizes of less than 27 millimeters and 27 or more millimeters. Median survival times and hazard ratios are included.

Figure 3. Intracranial responses according to the perilesional edema diameter. (A) CNS depth of intracranial responses according to the PED diameter. The Kaplan-Meier plot assessed the PED after radiotherapy according to (B) progression-free survival and (C) overall survival. MV analysis: PED (>27 mm) remained significant for 8 CNS PFS after the adjustment for sex, Lung-molGPA score, and gross tumor diameter. Cut Off PED was set at <27mm and ≥27mm. Two-tailed P values ≤ 0.05 were considered statistically significant (Bold values). PED, perilesional edema diameter; GTD, gross tumor diameter.

There was a mistake in reported values. A correction has been made to the section 3.4 Intracranial progression-free survival, third paragraph:

“The 6-month icPFS rate was also higher in the minor PED subgroup, 81.6% (95% CI 67.6 -89.9) versus 50.8% (95% CI 36.9 -63.1, p<0.001, respectively”.

There was a typo mistake in reported values. A correction has been made to the section 3.5 Overall survival, first paragraph:

“The 6-month OS rate was 80.3% (95% CI 66.5 -88.9) vs. 57.4% (95% CI 44.1 -68.7), p = 0.007, favoring those patients with a minor PED”.

The original version of this article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: central nervous system, tumor diameter, perilesional edema, lung adenocarcinoma, lung cancer, local therapy, radiation therapy

Citation: Arrieta O, Bolaño-Guerra LM, Caballé-Pérez E, Lara-Mejía L, Turcott JG, Gutiérrez S, Lozano-Ruiz F, Cabrera-Miranda L, Arroyave-Ramírez AM, Maldonado-Magos F, Corrales L, Martín C, Gómez-García AP, Cacho-Díaz B and Cardona AF (2025) Correction: Perilesional edema diameter associated with brain metastases as a predictive factor of response to radiotherapy in non-small cell lung cancer. Front. Oncol. 15:1726889. doi: 10.3389/fonc.2025.1726889

Received: 17 October 2025; Accepted: 17 November 2025;
Published: 03 December 2025.

Edited and reviewed by:

Lin Zhou, Sichuan University, China

Copyright © 2025 Arrieta, Bolaño-Guerra, Caballé-Pérez, Lara-Mejía, Turcott, Gutiérrez, Lozano-Ruiz, Cabrera-Miranda, Arroyave-Ramírez, Maldonado-Magos, Corrales, Martín, Gómez-García, Cacho-Díaz and Cardona. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Oscar Arrieta, b2dhcnJpZXRhQGdtYWlsLmNvbQ==

†ORCID: Oscar Arrieta, orcid.org/0000-0002-1164-3779
Enrique Caballé-Pérez, orcid.org/0000-0001-7703-6675
Luis Lara-Mejía, orcid.org/0000-0001-8101-4604
Ana Pamela Gómez-García, orcid.org/0000-0002-9392-1647

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.